Dose Of Vitamin D Quotes

I take 1 gram (1,000 mg) of NMN every morning, along with 1 gram of resveratrol (shaken into my homemade yogurt) and 1 gram of metformin.7 • I take a daily dose of vitamin D, vitamin K2, and 83 mg of aspirin.

The truth is that vitamin D isn't an analgesic, it's a super hormone that stimulates our body to behave. This means that vitamin D doesn’t take your pain away after 30 minutes. It can take

I take 1 gram (1,000 mg) of NMN every morning, along with 1 gram of resveratrol (shaken into my homemade yogurt) and 1 gram of metformin.7 • I take a daily dose of vitamin D, vitamin K2, and 83 mg of aspirin. • I strive to keep my sugar, bread, and pasta intake as low as possible. I gave up desserts at age 40, though I do steal tastes. • I try to skip one meal a day or at least make it really small. My busy schedule almost always means that I miss lunch most days of the week. • Every few months, a phlebotomist comes to my home to draw my blood, which I have analyzed for dozens of biomarkers. When my levels of various markers are not optimal, I moderate them with food or exercise. • I try to take a lot of steps each day and walk upstairs, and I go to the gym most weekends with my son, Ben; we lift weights, jog a bit, and hang out in the sauna before dunking in an ice-cold pool. • I eat a lot of plants and try to avoid eating other mammals, even though they do taste good. If I work out, I will eat meat. • I don’t smoke. I try to avoid microwaved plastic, excessive UV exposure, X-rays, and CT scans. • I try to stay on the cool side during the day and when I sleep at night. • I aim to keep my body weight or BMI in the optimal range for healthspan, which for me is 23 to 25.

Summary: Wheat Belly Detox Supplements Look for the supplements we use in the Wheat Belly 10-Day Grain Detox in health food stores. Because of regional variation in brands, the reputable brands that are available to you may differ from the ones I list below. Where national brands are widely distributed, I will specify a few quality representative ones. High-potency probiotic supplement: 30 billion to 50 billion CFUs per day for 6 to 8 weeks. My favorite brands include Garden of Life, Renew Life, and VSL#3, all of which contain a long list of preferred bacterial species, as well as high CFU counts. Vitamin D: 4,000 to 8,000 IUs per day to start for adults, as gelcaps or drops; long-term dose adjusted to achieve a 25-hydroxy vitamin D blood level of 60 to 70 ng/mL. Excellent vitamin D preparations are widely available in many brands and surprisingly low in cost. Look for oil-based gelcaps (that look like little fish oil capsules) or liquid drops, but not tablets. Even the big-box stores like Costco and Sam’s Club have excellent preparations. Magnesium: Preferably magnesium malate, 1,200 mg two or three times per day, or magnesium glycinate, 400 mg two or three times per day; or magnesium citrate, 400 mg two or three times per day. (If elemental magnesium—i.e., magnesium without the weight of malate, glycinate, or citrate—is specified on your supplement, aim for around 400 mg magnesium per day.) Source Naturals, NOW, and KAL are excellent brands. Fish oil: 3,000 to 3,600 mg per day of EPA and DHA, divided into two doses. Among my preferred brands are Nordic Naturals, Ascenta Nutra-Sea, and Carlson. Iodine: 500 to 1,000 mcg per day as potassium iodide drops or kelp tablets. Like vitamin D, there are many excellent preparations available at low cost. Iron: Look for supplements in the ferrous form and take only if low ferritin levels or iron deficiency anemia is identified; the dose depends on the severity of anemia and the form chosen. Sundown Naturals, Feosol, and Pure Encapsulations are among preferred brands. Zinc: 10 to 15 mg per day of (elemental) zinc as gluconate, sulfate, or acetate. Twinlab, Thorne, and NOW provide great choices.

SUPPLEMENT DAILY DOSAGE Vitamin A 10,000 IU or 6 mg beta-carotene (choose mixed carotenes if available)     B-complex vitamins B1, B2, B3, B5: 50 mg B6: 50 mg, or 100 mg if nauseated (can be higher: if necessary up to 250 mg to prevent nausea) B12: 400 mcg Choline, Inositol, PABA: 25 mg Biotin: 200 mcg Folic acid: 500 mcg (increase this to 1000 mcg if you have suffered a previous miscarriage, if there is a history of neural tube defects in your family, or if you are over 40 years of age)     Vitamin C 1–2 g (take the higher dose if you are exposed to toxicity or in contact with, or suffering from, infection)     Bioflavonoids 500–1000 mg (helpful for preventing miscarriage and breakthrough bleeding)     Vitamin D 200 IU     Vitamin E 500 IU (increasing to 800 IU during last trimester)     Calcium 800 mg (increasing to 1200 mg during middle trimester when your baby’s bones are forming, or if symptoms such as leg cramps indicate an increased need)     Magnesium 400 mg (half the dose of calcium)     Potassium 15 mg or as cell salt (potassium chloride, 3 tablets)     Iron Supplement only if need is proven; dosage depends on serum ferritin levels (stored iron) If levels < 30 mcg per litre, take 30 mg If levels < 45 mcg per litre, take 20 mg If levels < 60 mcg per litre, take 10 mg This test for ferritin levels should be repeated at the end of each trimester, and we give further details in Chapter 11.     Manganese 10 mg     Zinc 20–60 mg, taken last thing at night on an empty stomach (dose level to depend on results of zinc taste test, which ideally should be performed at two monthly intervals during your pregnancy; see page 172–174 for details)     Chromium 100–200 mcg (upper limit applies to those with sugar cravings or with proven need)     Selenium 100–200 mcg (upper limit for those exposed to high levels of heavy metal or chemical pollution). Selenium is best taken away from vitamin C, but can be taken with zinc.     Iodine 75 mcg (or take 150 mg of kelp instead)     Acidophilus/Bifidus Half to one teaspoonful, one to three times daily (upper limits for those who suffer from thrush)     Evening primrose oil 500–1000 mg two to three times daily     MaxEPA (or deep sea fish oils) 500–1000 mg two to three times daily     Garlic 2000–5000 mg (higher levels for those exposed to toxins)     Silica 20 mg     Copper 1–2 mg (but only if zinc levels are adequate)     Hydrochloric acid and digestive enzymes For those with digestive problems. There are numerous proprietary preparations which contain an appropriate combination of active ingredients. Ask your health practitioner, pharmacist or health food shop for guidance, and take as directed on the label.     Co-enzyme Q10 10 mg daily

Know each agent being used and relevant nutrient interactions and contraindications, especially when combinations of drugs are used. Selection of appropriate nutrients and botanicals is complex and based on many factors. General recommendations are safe for all types of chemotherapy. • Multiple vitamin: — Vitamin A: 5000 IU — Mixed natural carotenoids: 10,000-25,000 IU — B complex: 25-50 mg — Folic acid: 400-800 μg — Vitamin B12: 200-1000 μg — Vitamin E succinate: 400 IU — Vitamin C: 500-1000 mg — Vitamin D 400-800 IU — Trace minerals: full complement • Melatonin: 20 mg at bedtime • Vitamin C: 3000-10,000 mg q.d. in divided doses according to bowel tolerance • Fish oils: to provide 2 g total combined eicosapentaenoic acid and docosahexaenoic acid daily • Mushroom extracts/immune support: use a variety of immune modulators, switching them regularly to avoid downregulation of receptors. Standard doses for Coreolis versicolor mushroom is 3 g of the extract daily. Suggested dosage for maitake D fraction is 0.5-1.0 mg of extract per kilogram body weight. Other botanical immune modulators may be used as desired. • Enzymes: use pancreatic enzymes with meals and mixed enteric-coated enzymes between meals. • Green tea: capsules and beverages to total the equivalent of 5-10 cups daily. Caffeinated form is preferred if patient tolerates caffeine. • Whey protein shake: administer with fruit daily as a source of easily assimilated protein and amino acids, particularly glutamine.

Magnesium plays a central role in allowing your body to properly absorb calcium.  But magnesium doesn’t work alone, and that’s where vitamin D and vitamin K come in.  There is a growing body of evidence that suggests that if you want to correct a vitamin D deficiency by taking large doses of vitamin D, you also need to take vitamin K supplements.  The reason for this is that vitamin D (along with magnesium) is needed for the proper absorption of calcium.  However, it is vitamin K that is needed to then allow your bones to absorb the calcium.  In the absence of vitamin K or magnesium, that calcium can turn up in the worst possible place – your arteries. 

take 1 gram (1,000 mg) of NMN every morning, along with 1 gram of resveratrol (shaken into my homemade yogurt) and 1 gram of metformin.7 • I take a daily dose of vitamin D, vitamin K2, and 83 mg of aspirin.

In my experience, 2000 IU is an appropriate dose that most consistently brings most people into the favorable range for 25-hydroxy vitamin D on their blood test.

therefore advise people to take 4,000 to 8,000 international units (IUs) per day of oil-based vitamin D3, or cholecalciferol, in gelcaps or drops, for assured absorption. This dose is sufficient to achieve a 25-hydroxy vitamin D blood level of 60 to 70 ng/mL after 2 to 3 months of supplementation in the majority of people, just like a young lifeguard with a tan.

and plays on your vulnerabilities — you are not smart or strong or tall enough. Does it claim to be rich in a nutrient or have extra doses of a nutrient? Iron, fibre, protein, vitamin D? Textbook nutritionism (read previous chapter or ask your parents about it once they have read it). Is it giving you a free toy for buying the product or a chance to win an iPhone or an all-expenses paid foreign trip? Illegal in a lot of countries where governments are active in protecting children from the cheap and unethical marketing practices of food companies. Does your favourite movie star or cricketer endorse the product? Truth be told, you are only engaged as a brand ambassador of junk food when you have a fit and agile body. Essentially, it means that you have had the mental and physical discipline to stay away from the very food that you are endorsing. And to tell you a secret, the celebs won’t even consume it on the day of the shoot; they

As I see it, vitamin D3 at optimal doses is the ideal “weight loss drug” because it addresses three different factors: minimizing fat absorption in the small intestine, increasing the metabolism by twenty to thirty percent, and decreasing the appetite.

have come up with a list of new guidelines for Vitamin D3 dosing for doctors and Vitamin D3 researchers- -Never give a patient Vitamin D2. It is far inferior to Vitamin D3 for the intended purpose. Vitamin D2 is the hormone that plants make

and use, it is chemically different than the hormone animals make in their skin or on their fur when exposed to sunlight which is Vitamin D3. Vitamin D3 is much more effective, has a much stronger effect than D2 and a much longer half-life. Just stop using Vitamin D2 for anything! It is hereby banned! -Eliminate the practice of bolus injections of high doses of Vitamin D3.

Prescribe only daily doses of Vitamin D3 for patients and test subjects, doing anything else makes all data comparisons completely worthless. If we can all agree to daily dosing of Vitamin D3 we can then have a much more workable data set to work with by limiting the treatment to a single variable- the dose. Also, by eliminating the periodic bolus injection protocol we will also drastically reduce the risk of falls caused by high dose Vitamin D3 aggravating an underlying magnesium deficiency. -Never prescribe Vitamin D3 without also giving the patient magnesium and Vitamin K2.

NEVER give extra calcium to a patient receiving higher doses of Vitamin D3. The main possible danger of Vitamin D3 which practitioners are so wary of is hypercalcemia- so why on earth would you give a patient extra calcium with Vitamin D3? You should only do this if you also have them supplementing with significant amounts of Vitamin K2 to put the excess calcium in the blood back into the bones. Osteoporosis is likely better treated with Vitamin K2,

magnesium and boron dosing as opposed to calcium. Most diets contain plenty of calcium, so throwing more calcium at the bones is not going to fix the osteoporosis and more likely to cause soft tissue calcification problems. -One dose fits all is not a logical or smart way to gauge the effects of Vitamin D3.

I have found that two people of the same weight can take a certain dose of Vitamin D3 and have two completely different changes in the blood level of their D3. For example, I know of two people, about the same weight, they both started taking 20,000 IU of D3 per day. One’s blood level of D3 skyrocketed to 180+ ng/ml  while the other’s blood level barely budged from 30   to  50  ng/ml. We call them high responders and low responders. The reasons for this are not yet clear, but it might have to do with the differing levels of magnesium in their systems. Anyway, the highly preferred way to conduct research or monitor patients

safe upper limit for Vitamin D consumption is 10,000 IU per day (57); doses above this increase risk of renal calculi formation, especially

I take 1 gram (1,000 mg) of NMN every morning, along with 1 gram of resveratrol (shaken into my homemade yogurt) and 1 gram of metformin.7 • I take a daily dose of vitamin D, vitamin K2, and 83 mg of aspirin. • I strive to keep my sugar, bread, and pasta intake as low as possible. I gave up desserts at age 40, though I do steal tastes. • I try to skip one meal a day or at least make it really small. My busy schedule almost always means that I miss lunch most days of the week. • Every few months, a phlebotomist comes to my home to draw my blood, which I have analyzed for dozens of biomarkers. When my levels of various markers are not optimal, I moderate them with food or exercise. • I try to take a lot of steps each day and walk upstairs, and I go to the gym most weekends with my son, Ben; we lift weights, jog a bit, and hang out in the sauna before dunking in an ice-cold pool.

take 1 gram (1,000 mg) of NMN every morning, along with 1 gram of resveratrol (shaken into my homemade yogurt) and 1 gram of metformin.7 • I take a daily dose of vitamin D, vitamin K2, and 83 mg of aspirin. • I strive to keep my sugar, bread, and pasta intake as low as possible. I gave up desserts at age 40, though I do steal tastes. • I try to skip one meal a day or at least make it really small. My busy schedule almost always means that I miss lunch most days of the week. • Every few months, a phlebotomist comes to my home to draw my blood, which I have analyzed for dozens of biomarkers. When my levels of various markers are not optimal, I moderate them with food or exercise. • I try to take a lot of steps each day and walk upstairs, and I go to the gym most weekends with my son, Ben; we lift weights, jog a bit, and hang out in the sauna before dunking in an ice-cold pool. • I eat a lot of plants and try to avoid eating other mammals, even though they do taste good. If I work out, I will eat meat. • I don’t smoke. I try to avoid microwaved plastic, excessive UV exposure, X-rays, and CT scans. • I try to stay on the cool side during the day and when I sleep at night. • I aim to keep my body weight or BMI in the optimal range for healthspan, which for me is 23 to 25. About fifty times a day I’m asked about supplements.

Vitamin D3 boasts a strong safety profile, along with broad and deep evidence that links it to brain, metabolic, cardiovascular, muscle, bone, lung, and immune health. New and emerging research suggests that vitamin D supplements may also slow down our epigenetic/biological aging.29, 30 2. Omega-3 fish oil: Over the last thirty years or so, the typical Western diet has added more and more pro-inflammatory omega-6 polyunsaturated fatty acids versus anti-inflammatory omega-3 PUFAs. Over the same period, we’ve seen an associated rise in chronic inflammatory diseases, including obesity, cardiovascular disease, rheumatoid arthritis, and Alzheimer’s disease. 31 Rich in omega-3s, fish oil is another incredibly versatile nutraceutical tool with multi-pronged benefits from head to toe. By restoring a healthier PUFA ratio, it especially helps your brain and heart. Regular consumption of fatty fish like salmon has been linked to a lower risk of congestive heart failure, coronary heart disease, sudden cardiac death, and stroke.32 In an observational study, omega-3 fish oil supplementation was also associated with a slower biological clock.33 3. Magnesium deficiency affects more than 45 percent of the U.S. population. Supplements can help us maintain brain and cardiovascular health, normal blood pressure, and healthy blood sugar metabolism. They may also reduce inflammation and help activate our vitamin D. 4. Vitamin K1/K2 supports blood clotting, heart/ blood vessel health, and bone health.34 5. Choline supplements with brain bioavailability, such as CDP-Choline, citicoline, or alpha-GPC, can boost your body’s storehouse of the neurotransmitter acetylcholine and possibly support liver and brain function, while protecting it from age-related insults.35 6. Creatine: This one may surprise you, since it’s often associated with serious athletes and fitness buffs. But according to Dr. Lopez, it’s “a bona fide arrow in my longevity nutraceutical quiver for most individuals, and especially older adults.” As a coauthor of a 2017 paper by the International Society for Sports Nutrition, Dr. Lopez, along with contributors, stated that creatine not only enhances recovery, muscle mass, and strength in connection with exercise, but also protects against age-related muscle loss and various forms of brain injury.36 There’s even some evidence that creatine may boost our immune function and fat and carbohydrate metabolism. Generally well tolerated, creatine has a strong safety profile at a daily dose of three to five grams.37 7.

High doses of vitamin D for several months were needed to move from the low end of the medical testing range to the high end.

After researching light deficiency in my body, I was severely vitamin D deficient at just 9 ng/mL when I got tested later that year. I started sunbathing to try and fix it and when that did not work, I took high dosing vitamin D supplements for several months and that fixed it.

B.    A hormone is a molecule the body uses to send messages to its cells.

However, to give our body all the calcium it needs, eating calcium-rich foods may not be enough. Why? Because when calcium reaches the intestine it will only be absorbed in large quantities if there's enough vitamin D available.

For example, a study conducted in northern Finland collected data from more than 10,000 children. One of their findings was that children who took 2,000 IU of vitamin D during the first year of life had less than 80% chance of developing type 1 diabetes.[153]

In the case of type 2 diabetes, there seems to be a direct relationship between blood levels of vitamin D and the body's ability to deal with excess sugar. To put it in simple terms: The higher the levels of vitamin D in your blood, the lower your chances of developing type 2 diabetes.[154]

The truth is that vitamin D isn't an analgesic, it's a super hormone that stimulates our body to behave. This means that vitamin D doesn’t take your pain away after 30 minutes. It can take days, weeks or months. But it will be worth it.

There seems to be a link between vitamin D deficiency and fibromyalgia and chronic pain. In addition, in the case of the muscular and skeletal pain of autoimmune or inflammatory origin, vitamin D is the treatment of choice due to its rate of remission in the order of 95% obtained by the protocol of Dr. Coimbra in his clinical practice.

Throughout the book, we have observed the effects of vitamin D on cardiovascular disease, cancer, autoimmune diseases, depression, diabetes, chronic pain and many other health issues. Even burns recover better with vitamin D.[175]

from where it shouldn't be, protecting our arteries from calcium deposits and decreasing our chances of having a heart attack. What's more, it stimulates our bones and teeth to absorb calcium, thus offering vital help in preventing, and perhaps even in resolving, osteoporosis.

In real life, there are no superheroes with superpowers to defend us, but vitamin D and its faithful companion, vitamin K2, come close.

Now, our goal is to move calcium away from certain places — the wrong places. How can we do this? Oh, if only there was a molecule capable of moving calcium away from soft tissue! A molecule that, simultaneously, helped calcium to go to where it’s needed. Well, we know that this molecule exists, don’t we? It’s called vitamin K2.

We now understand how vitamin K2 directly relates to cardiovascular disease. Vitamin K2 helps in removing calcium deposits from arteries. Why is this so significant?

Because, as stated in the introduction of this chapter: "the buildup of calcium in the arteries feeding the heart is one of the major

risk factors [for heart disease].” This means the more calcium you have accumulated in your coronary arteries, the greater your chances of some blood ending up clotting there, causing you to suffer a heart attack.

Vitamin K2 is the key to understand why so many people supplement with calcium without success. Moreover, if you have osteoporosis and you aren’t taking vitamin K2, calcium supplements may even be harming you, because calcium will be more likely to end up being deposited in the wrong place. Of course, if you take high doses of vitamin D you don’t need to supplement with calcium since vitamin D is already helping your intestines in absorbing too much calcium.

Additionally, vitamin K2 attenuates the bone mineral loss promoted by vitamin D.

Therefore, by joining vitamin K2 to our basic regimen of vitamin D, magnesium chloride and vitamin B2, we'll be doing a favor to our arteries, our kidneys and our bones. What a wonderful vitamin!

for example, also contains vitamin K2. The major sources of this vitamin, however, are foods fermented by bacteria like Gouda cheese[103] and Natto, a traditional Japanese food made from fermented soybeans which is, perhaps, the largest natural source of vitamin K2.[104] When was the last time you saw someone eating Natto? Or worrying — and having the financial means — to feed regularly on meat, eggs and cheese from certified organic farms? No wonder then, that most of us are deficient in vitamin K2. Due to this, our body has a hard time moving calcium away from soft tissue and into bones and teeth — even despite its ability to convert some vitamin K1 into vitamin K2.

In clinical studies, doses of vitamin D varied between 400 and 18,400 IU. The results observed showed that vitamin D had at least the same effect as antidepressants — without the side effects.

seven different doses of vitamin D found that elderly women randomized to the medium doses (1,600, 2,400, or 3,200 units a day) were significantly less likely to fall than those given either the lower doses (400 or 800 units a day) or the higher doses (4,000 or 4,800 units a day).

All the scientists out there seem to be just churning out little puzzle pieces from their little area of expertise, and almost nobody is working on the puzzle! In fact if you look at the all the science journals out there, you will find that about 99% of them deal with results of experiments or clinical observations. I only know of one medical journal devoted to theory-Medical Hypotheses! That should tell you how dysfunctional our science community actually is! I believe most scientists are borderline autistics that love repetition, sameness, and are generally pedantic (enjoying correcting others) and, like autistic children , they get mad when the furniture is rearranged!

Monitoring and Supporting Hashimoto’s ​• ​After Hashimoto’s is assessed with a positive TPO and/or TGB serum antibody test, establish TH-1 or TH-2 dominance with an immunological serum test. Look at the percentage values, not the total. ​• ​A TH-1 serum profile includes interferon, IL-2, IL-12, interferon-gamma, and TNF alpha. ​• ​A TH-2 serum profile includes IL-4, IL-13 and IL-10. ​• ​If the TH-1 cytokines are high, then modulate the autoimmune condition by supporting the TH-2 pathway with TH-2 stimulators. ​• ​If the TH-2 cytokines are high, then support the TH-1 pathway with TH-1 stimulators. ​• ​A CD4/CD8 (T-suppressor cell/T-helper cell) ratio of 2 or higher is an indication that an active antigen is driving the autoimmune response. This test is also a baseline from which to monitor overall progress. ​• ​If an active antigen or hapten is at work, then stimulate the dominant TH pathway to eradicate the antigen or drive it into remission. ​• ​If both TH-1 and TH-2 stimulators make you feel worse, a hapten may be driving the autoimmune condition. In that case, restore the immune barriers. ​• ​In all instances, modulate immune T-helper cell response with therapeutic doses of emulsified vitamin D plus cofactors, fish oil, and liposomal glutathione and superoxide dismutase cream. Have a licensed healthcare practitioner qualified to work with vitamin D therapy prescribe the appropriate dose. ​• ​Add in nutritional compounds individually every three days to monitor response. ​• ​Remove gluten and possibly dairy from the diet and support other systems, organs, and functions in the body.  (Managing blood sugar, digestive function, and adrenal health using functional medicine principles is explained in later chapters.) ​• ​Monitor whether support is effective with follow-up TSH, CD4/CD8, and TH-1 and TH-2 cytokine tests.

Do you ever recommend low-dose naltrexone to your patients? For those reading this who aren’t familiar with low-dose naltrexone (LDN), I’ll give a brief explanation. Naltrexone is an FDA-approved medication, approved to help heroin and opium addicts by blocking opioid receptors. In 1985, Dr. Bernard Bihari experimented with lower doses of naltrexone and realized that it can modulate the immune system. Soon thereafter, it was found that LDN can benefit many people with autoimmune conditions, certain types of cancers, and some other chronic health conditions. While at times I recommend LDN to my patients, it’s not something I jump into for the following reasons: 1. LDN doesn’t do anything to address the cause of the problem. Although LDN can modulate the immune system, it doesn’t do anything to address the underlying cause of Hashimoto’s. However, some people choose to take LDN while simultaneously trying to detect and remove their triggers. 2. LDN isn’t always effective. Although I can’t say that I’ve had a lot of patients who have taken LDN, I’ve worked with enough people to see that LDN sometimes is effective, but, at other times, it doesn’t seem to help at all. 3. LDN can have a negative effect on sleep. Initially, it is common for LDN to interfere with sleep. However, this seems to be more common in those people who start with a higher dosage (i.e., 4.5 mg); thus, if this occurs, you would want to lower the dosage. Better yet, start with a lower dosage of LDN and then gradually increase it if necessary. When Do I Recommend Low-Dose Naltrexone? In most cases, I will recommend a natural treatment approach first, and if the person isn’t responding after a few months, then I’d consider LDN as an option. In addition, before someone takes LDN, it’s important to address certain imbalances in order to increase its effectiveness. For example, low or depressed vitamin D levels should be corrected before someone starts taking LDN. In addition, according to some healthcare professionals, having a Candida overgrowth also can make LDN less effective.

If you’d rather get into the habit of taking it daily, the once-a-day dosing is 50 mcg.11 Note that these doses are specific to cyanocobalamin, the preferred supplemental form of vitamin B12, as there is insufficient evidence to support the efficacy of the other forms, like methylcobalamin

In summary, I recommend the following supplements and daily doses: Vitamin B12: 100–500 mcg Vitamin D: 1,000–3,000 IU (depending on blood work) Zinc: 15–30 mg Vitamin K2: 25–50 mcg Iodine: 150–300 mcg DHA and EPA: 200–300 mg

Long term supplementation with high doses of Vitamin D significantly improved my mental functioning.

It took several months of high dosing with vitamin D to raise my levels from the low to high end of the medical testing range.

Too much vitamin D supplementation and not enough of the pure form can cause magnesium deficiency.  You also need to consume it in your food as well as take supplemental vitamin K2 with more magnesium. "Taking mega doses of vitamin D supplements without sufficient amounts of K2 and magnesium can lead to vitamin D toxicity and magnesium deficiency symptoms, which include inappropriate calcification.

Dr. JJ Cannell who is head of the US Vitamin D council, and his words will comfort you as he urges people to take 50,000 IU a day for 3 days at the first sign of a cold.

Do not take a lot of D3 unless you also take a lot of vitamin K2.

Step Two Test your limiting factors: (1) The kidneys and (2) the blood levels of PTH and (3) calcium. The basic tests for a protocol with doses higher than 10,000 IU involve testing the calcium in your urine to access your kidney function and testing your blood levels of PTH, calcium and vitamin D.

Maybe you have been taking a dose of vitamin D that you think is high enough, but if your PTH levels aren’t coming down this means you’re not taking enough vitamin D. If you aren't influencing the parathyroid, you can't be influencing the immune system.

the following tests used by Dr. Coimbra during the protocol — presented here with some minor modifications:[45] 1. Vitamin B12 2. Calcitriol 3. Calcifediol 4. PTH 5. Calcium (total and ionized) 6. Urea (BUN — Blood Urea Nitrogen) 7. Creatinine 8. Albumin 9. Ferritin 10. Chromium (serum) 11. Phosphate (serum) 12. Ammonia (serum) 13.  Complete amino acid profile 14. ALT 15. AST 16. TSH 17.  Serum alkaline phosphatase 18. Serum P1NP 19. Serum CTX 20.  Calcium in the urine of 24 hours (with total volume) 21.  Phosphate in the urine of 24 hours (with total volume) In addition to the calcium and phosphate blood tests, the following electrolytes could also be added: 22.  Ionogram (sodium, potassium, chloride, magnesium and bicarbonate)

The recommended dose is of at least 100 micrograms of vitamin K2 per 10,000 IU of vitamin D. In addition, high doses of vitamin D promote processes within the body that make extensive use of other nutrients, notably magnesium. Therefore, supplement your body with magnesium.

Four times a day: · 500 milligrams of DHA (a type of omega 3 fatty acid). · 5 milligrams of Zinc. · 120 milligrams of Choline. · 125-250 milligrams of Magnesium Chloride or Magnesium Glycinate. · 50 to 100 mg milligrams of Riboflavin — Vitamin B2. · 1,000 to 5,000 micrograms of Vitamin B12. · 500 micrograms of Folic Acid. · 150 micrograms of Chromium Picolinate. · 50 to 100 micrograms of Selenium. Once per day, optionally: · 100 micrograms of CoQ10.

Keep testing your blood and urine every 2 months and adjust your doses accordingly. If the tests reveal your kidneys are working well and your calcium metabolism is within the reference range, the next step will be to look at your PTH levels: ·         If PTH levels are below the lowest reference value, you’ll need to reduce the vitamin D you are taking. ·         If PTH levels are at the lowest value, but still within the reference range, you’ll need to maintain the same dose of vitamin D you have been taking. ·         If PTH is within the reference range, but not yet at the lowest value, it’s time to increase vitamin D supplementation. This is, by far, the most common scenario. You may increase doses by 10,000 IU or by 20,000 IU, or more, depending on how far away from our goal you are.