Dopamine Quotes

Nothing captures the biological argument better than the famous New Age slogan: ‘Happiness begins within.’ Money, social status, plastic surgery, beautiful houses, powerful positions – none of these will bring you happiness. Lasting happiness comes only from serotonin, dopamine and oxytocin.

Bending his head, Kai pressed his lips to her knuckles. The plating had no nerve endings, and yet the touch sent a tingle of electricity along her arm. “Cinder?” “Mm?” He lifted his gaze. “Just to be clear, you’re not using your mind powers on me right now, are you?” She blinked. “Of course not.” “Just checking.” Then he slid his arms around her waist and kissed her. Cinder gasped, pressing her palms against his chest. Kai pulled her closer. Seconds later, her brain began registering all the new chemicals flooding her system. INCREASED LEVELS OF DOPAMINE AND ENDORPHINS, REDUCED AMOUNTS OF CORTISOL, ERRATIC PULSE, RISING BLOOD PRESSURE … Leaning into him, Cinder sent the messages away. Her hands tentatively made their way to his shoulders, before stringing around his neck.

The exaggerated dopamine sensitivity of the introvert leads one to believe that when in public, introverts, regardless of its validity, often feel to be the center of (unwanted) attention hence rarely craving attention. Extroverts, on the other hand, seem to never get enough attention. So on the flip side it seems as though the introvert is in a sense very external and the extrovert is in a sense very internal - the introvert constantly feels too much 'outerness' while the extrovert doesn't feel enough 'outerness'.

That's what falling in love really amounted to, your brain on drugs. Adrenaline and dopamine, oxytocin and serotonin. Chemical insanity, celebrated by poets.

Evolution has no foresight. Complex machinery develops its own agendas. Brains — cheat. Feedback loops evolve to promote stable heartbeats and then stumble upon the temptation of rhythm and music. The rush evoked by fractal imagery, the algorithms used for habitat selection, metastasize into art. Thrills that once had to be earned in increments of fitness can now be had from pointless introspection. Aesthetics rise unbidden from a trillion dopamine receptors, and the system moves beyond modeling the organism. It begins to model the very process of modeling. It consumes evermore computational resources, bogs itself down with endless recursion and irrelevant simulations. Like the parasitic DNA that accretes in every natural genome, it persists and proliferates and produces nothing but itself. Metaprocesses bloom like cancer, and awaken, and call themselves I.

The paradox is that hedonism, the pursuit of pleasure for it's own sake, leads to anhedonia. Which is the inability to enjoy pleasure of any kind.

When the eyes of a woman that a man finds attractive look directly at him, his brain secretes the pleasure-inducing chemical dopamine - but not when she looks elsewhere.

Perempuan memang tidak bisa diajak berpikir jernih jika menyangkut perihal lelaki. Dalam situasi seperti ini, kepala mereka dipenuhi kabur merah muda bernama dopamine yang meracuni sel-sel kelabu mereka dengan berbagai ide romantis yang absurd.

Because we’ve transformed the world from a place of scarcity to a place of overwhelming abundance: Drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . the increased numbers, variety, and potency of highly rewarding stimuli today is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation.

Most people are about as happy as their self confidence will allow them to be.

Because what we associate with the idea of love is purely chemical. It can be broken down into scientifically proven phases: it starts with a dose of testosterone and estrogen, what we would think of as ‘lust,’ followed by the goofy ‘lovesick’ phase, which is a combination of adrenaline, dopamine, and a drop in serotonin levels—which, by the way, makes our brains behave exactly like the brains of crack addicts—and ends up, if we make it through phases one and two, with ‘attachment,’ where the body produces oxytocin and vasopressin, which basically make us want to cuddle excessively. It’s science. That’s all.

The warmth and satisfaction of positive contact with the adult is often just as good as a psychostimulant in supplying the child’s prefrontal cortex with dopamine.

Lessons of the balance. 1. The relentless pursuit of pleasure and avoidance of pain, leads to pain. 2. Recovery begins with abstinence 3. Abstinence rests the brains reward pathway and with it our capacity to take joy and simpler pleasures. 4. Self-binding creates literal and metacognitive space between desire and consumption, a modern necessity in our dopamine overloaded world. 5. Medications can restore homeostasis, but consider what we lose by medicating away our pain. 6. Pressing on the pain side, resets our balance to the side of pleasure. 7. Beware of getting addicted to pain. 8. Radical honesty promotes awareness, enhances intimacy and fosters a plenty mindset. 9. Prosocial shame affirms that we belong to the human tribe. 10. Instead of running away from the world, we can find escape by immersing ourselves in it.

People are attracted more towards bad things because being good has been turned into a boring duty. No adrenaline & dopamine rush, no rewards!

The reason we’re all so miserable may be because we’re working so hard to avoid being miserable.

Multitasking has been found to increase the production of the stress hormone cortisol as well as the fight-or-flight hormone adrenaline, which can overstimulate your brain and cause mental fog or scrambled thinking. Multitasking creates a dopamine-addiction feedback loop, effectively rewarding the brain for losing focus and for constantly searching for external stimulation. To make matters worse, the prefrontal cortex has a novelty bias, meaning that its attention can be easily hijacked by something new—the proverbial shiny objects

Love? Dopamine released in the brain, which gets depleted over time, leaving contempt.

In other words, dopamine is not about the happiness of reward. It's about the happiness of pursuit of reward that has a decent chance of occurring.

Money, social status, plastic surgery, beautiful houses, powerful positions – none of these will bring you happiness. Lasting happiness comes only from serotonin, dopamine and oxytocin.1

From dopamine’s point of view, having things is uninteresting. It’s only getting things that matters. If you live under a bridge, dopamine makes you want a tent. If you live in a tent, dopamine makes you want a house. If you live in the most expensive mansion in the world, dopamine makes you want a castle on the moon. Dopamine has no standard for good, and seeks no finish line. The dopamine circuits in the brain can be stimulated only by the possibility of whatever is shiny and new, never mind how perfect things are at the moment. The dopamine motto is “More.

What is love when it's not for dopamine?

High levels of dopamine suppress H&N functioning, so brilliant people are often poor at human relationships. We need H&N empathy to understand what’s going on in other people’s minds, an essential skill for social interaction.

But, there is a cost to medicating away every type of human suffering, and as we shall see, there is an alternative path that might work better: embracing pain.

...what draws us into a story and keeps us there is the firing of our dopamine neurons, signaling that intriguing information is on the way.

When a person sees someone attractive to them, their eyes dilate twenty percent. Their brain floods with dopamine, which makes them happy. Thus, they believe it’s love. That’s a medical fact. Love doesn’t exist.

Each happy chemical triggers a different good feeling. Dopamine produces the joy of finding what you seek– the “Eureka! I got it!” feeling. Endorphin produces the oblivion that masks pain– often called “euphoria.” Oxytocin produces the feeling of being safe with others– now called “bonding.” And serotonin produces the feeling of being respected by others–“pride.

I don't believe. Religion? Humans desperate to take out infinity insurance. Death? The great big nada. Love? Dopamine released in the brain, which gets depleted over time, leaving contempt.

For Abby, "friend" is a word whose sharp corners have been worn smooth by overuse. "I'm friends with the guys in IT," she might say, or "I'm meeting some friends after work." But she remembers when the word "friend" could draw blood. She and Gretchen spent hours ranking their friendships, trying to determine who was a best friend and who was an everyday friend, debating whether anyone could have two best friends at the same time, writing each other's names over and over in purple ink, buzzed on the dopamine high of belonging to someone else, having a total stranger choose you, someone who wanted to know you, another person who cared that you were alive.

Carol, I can’t describe how you make me feel. Wait, no, I can—you make my mind release pleasure-inducing neurotransmitters and you’ve flooded my mind with dopamine. If the experience of snorting cocaine and getting so high out of my mind that I want to climb a telephone pole with my bare hands just to see if I can do it were a person, it would be you.

You’d think people would realize they’re bad at multitasking and would quit. But a cognitive illusion sets in, fueled in part by a dopamine-adrenaline feedback loop, in which multitaskers think they are doing great.

[E]mpathy without accountability is a shortsighted attempt to relieve suffering.

We’re all running from pain. Some of us take pills. Some of us couch surf while binge-watching Netflix. Some of us read romance novels. We’ll do almost anything to distract ourselves from ourselves. Yet all this trying to insulate ourselves from pain seems only to have made our pain worse.

Giving in to craving doesn’t necessarily lead to pleasure because wanting is different from liking. Dopamine makes promises that it is in no position to keep. “If you buy these shoes, your life will change,” says the desire circuit, and it just might happen, but not because dopamine made you feel it.

Is that what God does? He helps? Tell me, why didn't God help my innocent friend who died for no reason while the guilty ran free? Okay. Fine. Forget the one offs. How about the countless wars declared in his name? Okay. Fine. Let's skip the random, meaningless murder for a second, shall we? How about the racist, sexist, phobia soup we've all been drowning in because of him? And I'm not just talking about Jesus. I'm talking about all organized religion. Exclusive groups created to manage control. A dealer getting people hooked on the drug of hope. His followers, nothing but addicts who want their hit of bullshit to keep their dopamine of ignorance. Addicts. Afraid to believe the truth. That there's no order. There's no power. That all religions are just metastasizing mind worms, meant to divide us so it's easier to rule us by the charlatans that wanna run us. All we are to them are paying fanboys of their poorly-written sci-fi franchise. If I don't listen to my imaginary friend, why the fuck should I listen to yours? People think their worship's some key to happiness. That's just how he owns you. Even I'm not crazy enough to believe that distortion of reality. So fuck God. He's not a good enough scapegoat for me.

We all know that feeling of wanting something so bad and then finally getting it. You feel this rush of dopamine, and then very soon after you crash and you need something else to give you that hit of dopamine. This is the vicious cycle that emerges from the empty promise of capitalism – that happiness comes from acquiring material possessions. The Native Americans have one of the most beautiful concepts in the world. They have 10,000 different languages and all these tribes and none of them have a word for ownership or possession. They know that they are just temporary stewards of the earth; no one can truly own anything.

Because of these exaggerated dopamine responses, once they focus on the chance to get a reward, psychopaths are unable to alter their attention until they get what they're after.

After kicking opiates, “it takes two years for your dopamine receptors to start working naturally,” Paul

Why would I waste time—a highly precious, constantly diminishing resource—on transitory neurological fluctuations of adrenaline, dopamine, and serotonin?

Dopamine can be read as the ultimate feminist chemical in the female brain.

...dopamine is not about the happiness of reward. It's about the happiness of pursuit of reward that has a decent chance of occurring.

I urge you to find a way to immerse yourself fully in the life that you’ve been given. To stop running from whatever you’re trying to escape, and instead to stop, and turn, and face whatever it is. Then I dare you to walk toward it. In this way, the world may reveal itself to you as something magical and awe-inspiring that does not require escape. Instead, the world may become something worth paying attention to.

Narcissistic Supply You get discarded as supply for one of two reason: They find you too outspoken about their abuse. They prefer someone that will keep stroking their ego and remain their silent doormat. Or, they found new narcissistic supply. Either way, you can count on the fact that they planned your devaluation phase and smear campaign in advance, so they could get one more ego stroke with your reaction. Narcissists are angry, spiteful takers that don't have empathy, remorse or conscience. They are incapable of unconditional love. Love to them is giving only when it serves them. They gaslight their victims by minimizing the trauma they have caused by blaming others or stating you are too sensitive. They never feel responsible or will admit to what they did to you. They have disordered thinking that is concerned with their needs and ego. It is not uncommon for them to hack their targets, in order to gain information about them. They enjoy mind games and control. This is their dopamine high. The sooner you distance yourself the healthier you will become. Narcissism can't be cured or prayed away. It is a mental disorder that turns the victims of its abuse into mental patients because it causes so much psychological manipulation.

Studies show any movement, but particularly walking, will ease anxiety when we’re in the middle of a stress hormone surge. Indeed, the studies show that a mere 20–30 minute walk, five times a week, will make people less anxious, as effectively as antidepressants. Even better, the effect is immediate—serotonin, dopamine and endorphins all increase as soon as you start moving.

Pornography causes release of adrenaline from an area in the brain called the locus coeruleus, and this makes the heart race in those who view, or even anticipate, viewing pornography. The sexual pleasure of pornography may be partially caused by release of dopamine from the ventral tegmental area, and this stimulates the nucleus accumbens, one of the key pleasure centers of the brain.

The reason we’re all so miserable may be because we’re working so hard to avoid being miserable.

As the neuroscientist, Daniel Freedman, who studies the foraging practices of Red Harvester ants, once remarked to me: "The world is sensory rich and causal poor". That is to say, we know the donut tastes good in the moment, but we are less aware that eating a donut every day for a month, adds 5 pounds to our waistline.

During times of physical separation, when touching and caressing is impossible, a deep, longing, almost a hunger, for the beloved can set in. We are used to thinking of this longing as only psychological, but it's actually physical. The brain is virtually in a drug-withdrawal state. During a separation, motivation for reunion can reach a fever pitch in the brain. Activities such as caressing, kissing, gazing, hugging, and orgasm can replenish the chemical bond of love and trust in the brain. The oxytocin-dopamine rush once again suppresses anxiety and skepticism and reinforces the love circuits in the brain. From an experiment we also know that oxytocin is naturally released in the brain after a twenty-second hug from a partner- sealing the bond between huggers and triggering the brain's trust circuits.

I urge you to find a way to immerse yourself fully in the life that you’ve been given. To stop running from whatever you’re trying to escape, and instead to stop, and turn, and face whatever it is. Then I dare you to walk toward it. In this way, the world may reveal itself to you as something magical and awe-inspiring that does not require escape. Instead, the world may become something worth paying attention to. The rewards of finding and maintaining balance are neither immediate nor permanent. They require patience and maintenance. We must be willing to move forward despite being uncertain of what lies ahead. We must have faith that actions today that seem to have no impact in the present moment are in fact accumulating in a positive direction, which will be revealed to us only at some unknown time in the future. Healthy practices happen day by day. My patient Maria said to me, “Recovery is like that scene in Harry Potter when Dumbledore walks down a darkened alley lighting lampposts along the way. Only when he gets to the end of the alley and stops to look back does he see the whole alley illuminated, the light of his progress.

Jessie?” “Hmmm?” “I’m glad we’re dating now.” Cue her arguments in 3…2…1… “We’re…not dating.” I grin at the ceiling. “Sure we are. We did it on my bed.” I shrug. “That means we’re dating.” “That’s not how it works!” she protests, raking a hand through her golden hair. “You don’t date people. Everyone says so. I mean, you’re just going there now because we had spectacular sex and you want more of it. It’s just the dopamine talking. I read up on this for my pharmacology exam.” I snort. “You’re saying I’m driving under the influence of orgasms?

Dopamine isn’t the pleasure molecule, after all. It’s the anticipation molecule. To enjoy the things we have, as opposed to the things that are only possible, our brains must transition from future-oriented dopamine to present-oriented chemicals, a collection of neurotransmitters we call the Here and Now molecules, or the H&Ns. Most people have heard of the H&Ns. They include serotonin, oxytocin, endorphins (your brain’s version of morphine), and a class of chemicals called endocannabinoids (your brain’s version of marijuana). As opposed to the pleasure of anticipation via dopamine, these chemicals give us pleasure from sensation and emotion. In fact, one of the endocannabinoid molecules is called anandamide, named after a Sanskrit word that means joy, bliss, and delight.

In time, as if by magic, we will realize that we have developed a deep bond with this person. The madness and excitement and spontaneity of the dopamine hit is replaced by a more relaxed, more stable, more long-term oxytocin-driven relationship. A vastly more valuable state if we have to rely on someone to help us do things and protect us when we’re weak. My favorite definition of love is giving someone the power to destroy us and trusting they won’t use it.

each is associated with different neurochemicals. Lust is associated primarily with the hormone testosterone in both men and women. Romantic love is linked with the natural stimulant dopamine and perhaps norepinephrine and serotonin. And feelings of male-female attachment are produced primarily by the hormones oxytocin and vasopressin. Moreover,

Beyond extreme examples of running from pain, we’ve lost the ability to tolerate even minor forms of discomfort. We’re constantly seeking to distract ourselves from the present moment, to be entertained.

The feelings of excitement, enthusiasm, and energy dissipate. Dopamine has shut down. Dopamine circuits don’t process experience in the real world, only imaginary future possibilities. For many people it’s a letdown. They’re so attached to dopaminergic stimulation that they flee the present and take refuge in the comfortable world of their own imagination. “What will we do tomorrow?” they ask themselves as they chew their food, oblivious to the fact that they’re not even noticing this meal they had so eagerly anticipated. To travel hopefully is better than to arrive is the motto of the dopamine enthusiast.

May your cortisol levels stay low, your dopamine levels high, your oxytocin run thick and rich, your serotonin build to a lovely plateau, and your ability to watch your brain at work keep you fascinated until your last breath. I wish you well on your journey.

You know when you send a text message to someone and you don't get a response right away, you feel depressed? You send a text message to someone you really like and you get a response right away you feel happy? You feel happy, the body, it creates the chemical dopamine, the dopamine, it goes through your blood and you become addicted to that dopamine rush, and you associate that dopamine rush with the happy feeling of receiving the text, and that's why you got people sending 3,000 fucking text messages a day, right, we're not even paying attention to what we're saying anymore it's just like a, like a morphine drip, right, it's like a dopamine drip! HAPPY BUTTONS! HAPPY BUTTONS! HAPPY BUTTONS! TIME TO PLAY WITH THE HAPPY BUTTONS!

You can change dopamine and the dorsal striatum with exercise. You can boost serotonin with a massage. You can make decisions and set goals to activate the ventromedial prefrontal cortex. You can reduce amygdala activity with a hug and increase anterior cingulate activity with gratitude. You can enhance prefrontal norepinephrine with sleep.

Exercise increases many of the neurotransmitters involved in positive mood regulation: dopamine, serotonin, norepinephrine, epinephrine, endocannabinoids, and endogenous opioid peptides (endorphins). Exercise contributes to the birth of new neurons and supporting glial cells. Exercise even reduces the likelihood of using and getting addicted to drugs.

The thought process that went into building these applications, Facebook being the first of them, . . . was all about: “How do we consume as much of your time and conscious attention as possible?” And that means that we need to sort of give you a little dopamine hit every once in a while, because someone liked or commented on a photo or a post or whatever.

Trick #3—excitement is not the same thing as fulfillment

Take dopamine. Elevated levels of dopamine in the brain produce extremely focussed attention,2 as well as unwavering motivation and goal-directed behaviors.3 These are central characteristics of romantic love. Lovers intensely focus on the beloved, often to the exclusion of all around them. Indeed, they concentrate so relentlessly on the positive qualities of the adored one that they easily overlook his or her negative traits;4 they even dote on specific events and objects shared with this sweetheart.

There are few things ever dreamed of, smoked or injected that have as addictive an effect on our brains as technology. This is how our devices keep us captive and always coming back for more. The definitive Internet act of our times is a perfect metaphor for the promise of reward: we search. And we search. And we search some more, clicking that mouse like – well, like a rat in a cage seeking another “hit”, looking for the elusive reward that will finally feel like enough.

When a monkey loses a banana to a rival, he feels bad, but he doesn't expand the problem by thinking about it over and over. He looks for another banana. He ends up feeling rewarded rather than harmed. Humans use their extra neurons to construct theories about bananas and end up constructing pain.

This brings up a key concept, namely the inverted U. The complete absence of stress is aversively boring. Moderate, transient stress is wonderful—various aspects of brain function are enhanced; glucocorticoid levels in that range enhance dopamine release; rats work at pressing levers in order to be infused with just the right amount of glucocorticoids. And as stress becomes more severe and prolonged, those good effects disappear (with, of course, dramatic individual differences as to where the transition from stress as stimulatory to overstimulatory occurs; one person’s nightmare is another’s hobby).

Love is nothing more than elevated levels of dopamine, nor-epinephrine, and other chemicals. But the way Uncle Antionio's face lights up as they dance... I wonder what it would be like to feel that. To let the chemicals of romance take over for just a little while. Then I remember that I am immortal and that my body doesn't work like everyone else's. Who knows if I can even feel love?

Cynicism is popular because it stimulates the brain chemicals that make you feel good. It stimulates dopamine by making the world feel predictable. It triggers serotonin by making you feel superior to “the jerks.” It triggers oxytocin by telling you who to trust. You pay a high price for these moments, unfortunately, because cynicism keeps you focused on problems instead of opportunities.

According to scientists, there are three stages of love: lust, attraction, and attachment. And, it turns out, each of the stages is orchestrated by chemicals—neurotransmitters—in the brain. As you might expect, lust is ruled by testosterone and estrogen. The second stage, attraction, is governed by dopamine and serotonin. When, for example, couples report feeling indescribably happy in each other’s presence, that’s dopamine, the pleasure hormone, doing its work. Taking cocaine fosters the same level of euphoria. In fact, scientists who study both the brains of new lovers and cocaine addicts are hard-pressed to tell the difference. The second chemical of the attraction phase is serotonin. When couples confess that they can’t stop thinking about each other, it’s because their serotonin level has dropped. People in love have the same low serotonin levels as people with OCD. The reason they can’t stop thinking about each other is that they are literally obsessed. Oxytocin and vasopressin control the third stage: attachment or long-term bonding. Oxytocin is released during orgasm and makes you feel closer to the person you’ve had sex with. It’s also released during childbirth and helps bond mother to child. Vasopressin is released postcoitally. Natasha knows these facts cold. Knowing them helped her get over Rob’s betrayal. So she knows: love is just chemicals and coincidence. So why does Daniel feel like something more?

but we have reached the point now where even the most sublime experience of Nature on Earth has devolved into just one more means to an end to getting likes on social media. People are dancing with the possibility of death just to steal a little dopamine rush to the brain which will wear off in a few seconds anyway and for a status update which will be buried by the algorithm after just 24 hours due to a lack of relevance.

She and Gretchen spent hours ranking their friendships, trying to determine who was a best friend and who was an everyday friend, debating whether anyone could have two best friends at the same time, writing each other’s names over and over in purple ink, buzzed on the dopamine high of belonging to someone else, having a total stranger choose you, someone who wanted to know you, another person who cared that you were alive.

With prolonged and repeated exposure to pleasurable stimuli, our capacity to tolerate pain decreases, and our threshold for experiencing pleasure increases.

If you want to be happy with your music all the time, start exposing yourself to unfamiliar music now, so it will be in the sweet spot by the time you’ve worn out the old pleasures.

The nucleus accumbens, a region of the forebrain associated with pleasure, grows to its largest size in one’s teenage years. At the same time, the body produces more dopamine, the neurotransmitter that conveys pleasure, than it ever will again. That is why the sensations you feel as a teenager are more intense than at any other time of life. But it also means that seeking pleasure is an occupational hazard for teenagers. The leading cause of deaths among teenagers is accidents—and the leading cause of accidents is simply being with other teenagers. When more than one teenager is in a car, for instance, the risk of an accident multiplies by 400 percent.

With intermittent exposure to pain, our natural hedonic set point gets weighted to the side of pleasure, such that we become less vulnerable to pain and more able to feel pleasure over time.

In his book In This Very Life, the Burmese meditation teacher Sayadaw U Pandita, wrote, "In their quest for happiness, people mistake excitement of the mind for real happiness." We get excited when we hear good news, start a new relationship, or ride a roller coaster. Somewhere in human history, we were conditioned to think that the feeling we get when dopamine fires in our brain equals happiness. Don't forget, this was probably set up so that we would remember where food could be found, not to give us the feeling "you are now fulfilled." To be sure, defining happiness is a tricky business, and very subjective. Scientific definitions of happiness continue to be controversial and hotly debated. The emotion doesn't seem to be something that fits into a survival-of-the-fittest learning algorithm. But we can be reasonably sure that the anticipation of a reward isn't happiness.

After three of four years of schooling, the nucleus basalis, which forms sharp memories in the brain, falls into disuse and decays. This is the part of the brain that makes learning so effortless for small children, and it is always activated in undomesticated humans. But neuroplasticity research has shown that damage to the nucleus basalis can be reversed by reintroducing activities involving highly focused attention, which results in massive increases in production of acetylcholine and dopamine. Using new skills under conditions of intense focus rewires billions of neural connections and reactivates the nucleus basalis. Loss of function in this part of the brain is not a natural stage of development--we are supposed to retain and even increase it throughout our lives. Until very recently in human history, we did.

Most people think love comes from the heart or soul. The heart simply pumps blood, so love can't be created there. Where is the center for what appears to be a person's soul? The Brain. And what is created there, Jilly? That's right--dopamine. What does dopamine do? Creates feelings of love and euphoria. How do we get our brains to create more? Drugs, massage, and/or sex. Boil it down and it's all just dopamine.

Here’s my point. The world is working against you. There will always be someone trying to grab your attention. As such, you have two choices. You can protect your focus by building habits and systems, or you can remain unprepared and let anyone distract you from the important things you should be doing with your time.

By protecting our children from adversity, have we made them deathly afraid of it? By bolstering their self-esteem with false praise and a lack of real-world consequences, have we made them less tolerant, more entitled, and ignorant of their own character defects? By giving in to their every desire, have we encouraged a new age of hedonism?

Pleasure and pain are co-located. In addition to the discovery of dopamine, neuro-scientists have determined that pleasure and pain are processed in overlapping brain regions, and work via an opponent processing mechanism. Another way to say this is pleasure and pain work like a balance. Imagine our brains contains a balance, a scale with a fulcrum in the centre. When nothing is on the balance it's level with the ground. When we experience pleasure, dopamine is released in our reward pathway and the balance tips to the side of pleasure. The more our balance tips and the faster it tips, the more pleasure we feel. But here's the important thing about the balance. It wants to remain level! that is, in equilibrium. It does not want to be tipped for very long, to one side or another. Hence, everytime the balance tips towards pleasure, powerful self-regulating mechanisms kick into action to bring it level again. These self-regulating mechanisms do not require conscious thought or an act of will, they just happen like a reflex.

This,” Alaric explained to Sarah in what he thought was a kindly voice, “isn’t love you’re feeling. Only dopamine. Because Felix isn’t like anyone else you know. Being a creature of the night, he’s new and exciting and activates a neurotransmitter in your brain that releases feelings of euphoria when you’re around him…especially because you know you can never actually be together, and he seems complicated, and perhaps even sensitive and vulnerable at times. But I can assure you: he’s anything but.” “How dare you?” Sarah demanded hotly. “It isn’t dopa…whatever! It’s love! Love!

What science offers for explaining the feelings we experience when believing in God or falling in love is complementary, not conflicting; additive, not detractive. I find it deeply interesting to know that when I fall in love with someone my initial lustful feelings are enhanced by dopamine, a neurohormone produced by the hypothalamus that triggers the release of testosterone, the hormone that drives sexual desire, and that my deeper feelings of attachment are reinforced by oxytocin, a hormone synthesized in the hypothalamus and secreted into the blood by the pituitary. Further, it is instructive to know that such hormone-induced neural pathways are exclusive to monogamous pair-bonded species as an evolutionary adaptation for the long-term care of helpless infants. We fall in love because our children need us! Does this in any way lessen the qualitative experience of falling in love and doting on one’s children? Of course not, any more than unweaving a rainbow into its constituent parts reduces the aesthetic appreciation of the rainbow.

One stretch of the gene is repeated a variable number of times, and the version with seven repeats (the “7R” form) produces a receptor protein that is sparse in the cortex and relatively unresponsive to dopamine. This is the variant associated with a host of related traits—sensation and novelty seeking, extroversion, alcoholism, promiscuity, less sensitive parenting, financial risk taking, impulsivity, and, probably most consistently, ADHD (attention-deficit/hyperactivity disorder).

70% of the world global deaths are attributable to modifial behavioural risk factors like smoking, physical inactivity and diet. The leading global risks for mortality are high blood pressure 13%, tobacco use 9%, high blood sugar 6%, physical inactivity 6% and obesity 5%. In 2013, an estimated 2.1 billion adults were overweight, compared with 857 million in 1980. There are now more people world-wide, except in sub-Saharan parts of Africa and Asia who are obese, than who are underweight.

[Texting] discourages thoughtful discussion or any level of detail. And the addictive problems are compounded by texting's hyperimmediacy. E-mails take some time to work their way through the Internet, through switches and routers and servers, and they require that you take the step of explicitly opening them. Text messages magically appear on the screen of your phone and demand immediate attention from you. Add to that the social expectation that an unanswered text feels insulting to the sender, and you've got a recipe for addiction: You receive a text, and that activates your novelty centers. You respond and feel rewarded for having completed a task (even though that task was entirely unknown to you fifteen seconds earlier). Each of those delivers a shot of dopamine as your limbic system cries out "More! More! Give me more!

Conspiracy theories are really attractive. Figuring out patterns is one of the things that gets your brain to give you a nice dose of chemical reward, the little ping of dopamine and whatever else that keeps you smiling. As a result, your brain is pretty good at finding patterns, and at disregarding information that doesn’t fit. Which means it’s also pretty good at finding false patterns, and at confirmation bias, and a bunch of other things that can be fatal. Our brains are also really good at making us the center of a narrative, because it’s what we evolved for.

Once we get the anticipated reward, brain dopamine firing increases well above tonic baseline, but if the reward we anticipated doesn't materialise, dopamine levels fall well below baseline. Which is to say, if we get the expected reward, we get an even bigger spike, if we don't get the expected reward, we experience an even bigger plunge. We've all experienced the letdown of unmet expectations. An expected reward that failed to materialise is worse than a reward that was never anticipated in the first place. How does cue-induced craving translate to our pleasure-pain balance? The balance tips to the side of pleasure, a dopamine mini spike, in anticipation of future reward. Immediately followed by a tip to the side of pain, a dopamine mini defecit, in the aftermath of the cue. The dopamine defecit is craving and drives drug seeking behaviour.

In other words, once reward contingencies are learned, dopamine is less about reward than about its anticipation. Similarly, work by my Stanford colleague Brian Knutson has shown dopamine pathway activation in people in anticipation of a monetary reward.91 Dopamine is about mastery and expectation and confidence. It’s “I know how things work; this is going to be great.” In other words, the pleasure is in the anticipation of reward, and the reward itself is nearly an afterthought (unless, of course, the reward fails to arrive, in which case it’s the most important thing in the world). If you know your appetite will be sated, pleasure is more about the appetite than about the sating.fn48 This is hugely important.

The more a sufferer concentrates on his symptoms, the deeper those symptoms are etched into his neural circuits. In the worst cases, the mind essentially trains itself to be sick. Many addictions, too, are reinforced by the strengthening of plastic pathways to the brain. Even very small doses of addictive drugs can dramatically alter the flow of neurotransmitters in a person’s synapses, resulting in long-lasting alterations in brain circuitry and function. In some cases, the buildup of certain kinds of neurotransmitters, such as dopamine, a pleasure-producing cousin to adrenaline, seems to actually trigger the turning on or off particular genes, bringing even stronger cravings for the drug. The vital path turns deadly.

The victim narrative reflects a wider societal trend in which we’re all prone to seeing ourselves as the victims of circumstance and deserving of compensation or reward for our suffering. Even when people have been victimized, if the narrative never moves beyond victimhood, it’s difficult for healing to occur.

Practicing mindfulness is something like observing the Milky Way. It demands that we see our thoughts and emotions as separate from us, and yet, simultaneously apart of us. Also the brain can do some pretty weird things, some of which are embarrassing, thus the importance of being without judgement. Reserving judgement is important to the practice of mindfulness because as soon as we start condemning what our brain is doing, eww, why would I be thinking about that, I'm a loser, I'm a freak - We stop being able to observe. Staying in the observer position is essential to getting to know our brains and ourselves in a new way.

People who live with ADHD are at high risk of addiction, especially adolescents, because of their poorly functioning frontal lobes. Years ago, when the illness was less well understood, doctors and parents were reluctant to give these vulnerable children addictive drugs such as Ritalin and amphetamine. It sounded reasonable: don’t give addictive substances to people at risk for addiction. But rigorous testing showed unambiguously that adolescents who were treated with stimulant drugs were less likely to develop addictions. In fact, those who started the drug at the youngest age and took the highest doses were the least likely to develop problems with illicit drugs. Here’s why: if you strengthen the dopamine control circuit, it’s a lot easier to make wise decisions. On the other hand, if effective treatment is withheld, the weakness of the control circuit is not corrected. The desire circuit acts unopposed, increasing the likelihood of high-risk, pleasure-seeking behavior.

Instead of taking a bow for walking on the moon, Colonel Buzz Aldrin, PhD, told his admirers, “It’s something we did. Now we should do something else,” apparently no more satisfied than if he had painted a fence. His desire was not to bask in his glory but to find “something else”—the next big challenge that could hold his interest. This perpetual need to identify a goal and calculate a way to reach it was perhaps the most important factor in his historic success. But it’s not easy having so much dopamine coursing through the control circuits. It almost certainly played a significant role in Aldrin’s post-lunar struggle with depression, alcoholism, three divorces, suicidal impulses, and a stay on a psychiatric ward, which he described in his candid autobiography, Magnificent Desolation: The Long Journey Home from the Moon.

I was diagnosed with ADHD in my mid fifties and I was given Ritalin and Dexedrine. These are stimulant medications. They elevate the level of a chemical called dopamine in the brain. And dopamine is the motivation chemical, so when you are more motivated you pay attention. Your mind won't be all over the place. So we elevate dopamine levels with stimulant drugs like Ritalin, Aderall, Dexedrine and so on. But what else elevates Dopamine levels? Well, all other stimulants do. What other stimulants? Cocaine, crystal meth, caffeine, nicotine, which is to say that a significant minority of people that use stimulants, illicit stimulants, you know what they are actually doing? They're self-medicating their ADHD or their depression or their anxiety. So on one level (and we have to go deeper that that), but on one level addictions are about self-medications. If you look at alcoholics in one study, 40% of male adult alcoholics met the diagnostic criteria for ADHD? Why? Because alcohol soothes the hyperactive brain. Cannabis does the same thing. And in studies of stimulant addicts, about 30% had ADHD prior to their drug use. What else do people self-medicate? Someone mentioned depression. So, if you have been treated for depression, as I have been, and you were given a SSRI medication, these medications elevate the level of another brain chemical called serotonin, which is implicated in mood regulation. What else elevates serotonin levels temporarily in the brain? Cocaine does. People use cocaine to self-medicate depression. People use alcohol, cannabis and opiates to self-medicate anxiety. Incidentally people also use gambling or shopping to self-medicate because these activities also elevate dopamine levels in the brain. There is no difference between one addiction and the other. They're just different targets, but the brain systems that are involved and the target chemicals are the same, no matter what the addiction. So people self-medicate anxiety, depression. People self-medicate bipolar disorder with alcohol. People self-medicate Post-Traumatic-Stress-Disorder. So, one way to understand addictions is that they're self-medicating. And that's important to understand because if you are working with people who are addicted it is really important to know what's going on in their lives and why are they doing this. So apart from the level of comfort and pain relief, there's usually something diagnosible that's there at the same time. And you have to pay attention to that. At least you have to talk about it.

Case in point: Warnings on cigarette packages can increase a smoker’s urge to light up. A 2009 study found that death warnings trigger stress and fear in smokers—exactly what public health officials hope for. Unfortunately, this anxiety then triggers smokers’ default stress-relief strategy: smoking. Oops. It isn’t logical, but it makes sense based on what we know about how stress influences the brain. Stress triggers cravings and makes dopamine neurons even more excited by any temptation in sight. It doesn’t help that the smoker is—of course—staring at a pack of cigarettes as he reads the warning. So even as a smoker’s brain encodes the words “WARNING: Cigarettes cause cancer” and grapples with awareness of his own mortality, another part of his brain starts screaming, “Don’t worry, smoking a cigarette will make you feel better!

A lizard never thinks something is wrong with the world, even as it watches its young get eaten alive. It doesn't tell itself "something is wrong with the world," because it doesn't have enough neurons to imagine the world being other than what it is. It doesn't expect a world in which there is no predators, so it doesn't condemn the world for falling short of expectations. it doesn't condemn itself for failing to keep its offspring alive. Humans expect more, and we do something about it. That's why we end up focused on our disappointments instead of saluting our accomplishments.

Throughout the human life span there remains a constant two-way interaction between psychological states and the neurochemistry of the frontal lobes, a fact that many doctors do not pay enough attention to. One result is the overreliance on medications in the treatment of mental disorders. Modern psychiatry is doing too much listening to Prozac and not enough listening to human beings; people’s life histories should be given at least as much importance as the chemistry of their brains. The dominant tendency is to explain mental conditions by deficiencies of the brain’s chemical messengers, the neurotransmitters. As Daniel J. Siegel has sharply remarked, “We hear it said everywhere these days that the experience of human beings comes from their chemicals.” Depression, according to the simple biochemical model, is due to a lack of serotonin — and, it is said, so is excessive aggression. The answer is Prozac, which increases serotonin levels in the brain. Attention deficit is thought to be due in part to an undersupply of dopamine, one of the brain’s most important neurotransmitters, crucial to attention and to experiencing reward states. The answer is Ritalin. Just as Prozac elevates serotonin levels, Ritalin or other psychostimulants are thought to increase the availability of dopamine in the brain’s prefrontal areas. This is believed to increase motivation and attention by improving the functioning of areas in the prefrontal cortex. Although they carry some truth, such biochemical explanations of complex mental states are dangerous oversimplifications — as the neurologist Antonio Damasio cautions: "When it comes to explaining behavior and mind, it is not enough to mention neurochemistry... The problem is that it is not the absence or low amount of serotonin per se that “causes” certain manifestations. Serotonin is part of an exceedingly complicated mechanism which operates at the level of molecules, synapses, local circuits, and systems, and in which sociocultural factors, past and present, also intervene powerfully. The deficiencies and imbalances of brain chemicals are as much effect as cause. They are greatly influenced by emotional experiences. Some experiences deplete the supply of neurotransmitters; other experiences enhance them. In turn, the availability — or lack of availability — of brain chemicals can promote certain behaviors and emotional responses and inhibit others. Once more we see that the relationship between behavior and biology is not a one-way street.

Environmental influences also affect dopamine. From animal studies, we know that social stimulation is necessary for the growth of the nerve endings that release dopamine and for the growth of receptors that dopamine needs to bind to in order to do its work. In four-month-old monkeys, major alterations of dopamine and other neurotransmitter systems were found after only six days of separation from their mothers. “In these experiments,” writes Steven Dubovsky, Professor of Psychiatry and Medicine at the University of Colorado, “loss of an important attachment appears to lead to less of an important neurotransmitter in the brain. Once these circuits stop functioning normally, it becomes more and more difficult to activate the mind.” A neuroscientific study published in 1998 showed that adult rats whose mothers had given them more licking, grooming and other physical-emotional contact during infancy had more efficient brain circuitry for reducing anxiety, as well as more receptors on nerve cells for the brain’s own natural tranquilizing chemicals. In other words, early interactions with the mother shaped the adult rat’s neurophysiological capacity to respond to stress. In another study, newborn animals reared in isolation had reduced dopamine activity in their prefrontal cortex — but not in other areas of the brain. That is, emotional stress particularly affects the chemistry of the prefrontal cortex, the center for selective attention, motivation and self-regulation. Given the relative complexity of human emotional interactions, the influence of the infant-parent relationship on human neurochemistry is bound to be even stronger. In the human infant, the growth of dopamine-rich nerve terminals and the development of dopamine receptors is stimulated by chemicals released in the brain during the experience of joy, the ecstatic joy that comes from the perfectly attuned mother-child mutual gaze interaction. Happy interactions between mother and infant generate motivation and arousal by activating cells in the midbrain that release endorphins, thereby inducing in the infant a joyful, exhilarated state. They also trigger the release of dopamine. Both endorphins and dopamine promote the development of new connections in the prefrontal cortex. Dopamine released from the midbrain also triggers the growth of nerve cells and blood vessels in the right prefrontal cortex and promotes the growth of dopamine receptors. A relative scarcity of such receptors and blood supply is thought to be one of the major physiological dimensions of ADD. The letters ADD may equally well stand for Attunement Deficit Disorder.

I tend to imagine the self-regulating system like little gremlins hoping on the pain side of the balance to counteract the weight on the pleasure side. The gremlins represent the work of homeostasis, the tendency of any living system to maintain physiologic equilibrium. Once the balance is level, it keeps going, tipping an equal and opposite amount to the side of pain. In the 1970s social scientists Richard Solomon and John Corbett called this reciprocal relationship between pleasure and pain "The Opponent Process Theory". Any prolonged or repeated departure from hedonic or adaptive neutrality has a cost. That cost is an after-reaction, that is opposite in value to the stimulus, or as the old saying goes: "What goes up, must come down".

I suggested she try walking to class without listening to anything and just letting her own thoughts bubble to the surface. She looked at me both incredulous and afraid. “Why would I do that?” she asked, openmouthed. “Well,” I ventured, “it’s a way of becoming familiar with yourself. Of letting your experience unfold without trying to control it or run away from it. All that distracting yourself with devices may be contributing to your depression and anxiety. It’s pretty exhausting avoiding yourself all the time. I wonder if experiencing yourself in a different way might give you access to new thoughts and feelings, and help you feel more connected to yourself, to others, and to the world.” She thought about that for a moment. “But it’s so boring,” she said. “Yes, that’s true,” I said. “Boredom is not just boring. It can also be terrifying. It forces us to come face-to-face with bigger questions of meaning and purpose. But boredom is also an opportunity for discovery and invention. It creates the space necessary for a new thought to form, without which we’re endlessly reacting to stimuli around us, rather than allowing ourselves to be within our lived experience.

Hey Pete. So why the leave from social media? You are an activist, right? It seems like this decision is counterproductive to your message and work." A: The short answer is I’m tired of the endless narcissism inherent to the medium. In the commercial society we have, coupled with the consequential sense of insecurity people feel, as they impulsively “package themselves” for public consumption, the expression most dominant in all of this - is vanity. And I find that disheartening, annoying and dangerous. It is a form of cultural violence in many respects. However, please note the difference - that I work to promote just that – a message/idea – not myself… and I honestly loath people who today just promote themselves for the sake of themselves. A sea of humans who have been conditioned into viewing who they are – as how they are seen online. Think about that for a moment. Social identity theory run amok. People have been conditioned to think “they are” how “others see them”. We live in an increasing fictional reality where people are now not only people – they are digital symbols. And those symbols become more important as a matter of “marketing” than people’s true personality. Now, one could argue that social perception has always had a communicative symbolism, even before the computer age. But nooooooothing like today. Social media has become a social prison and a strong means of social control, in fact. Beyond that, as most know, social media is literally designed like a drug. And it acts like it as people get more and more addicted to being seen and addicted to molding the way they want the world to view them – no matter how false the image (If there is any word that defines peoples’ behavior here – it is pretention). Dopamine fires upon recognition and, coupled with cell phone culture, we now have a sea of people in zombie like trances looking at their phones (literally) thousands of times a day, merging their direct, true interpersonal social reality with a virtual “social media” one. No one can read anymore... they just swipe a stream of 200 character headlines/posts/tweets. understanding the world as an aggregate of those fragmented sentences. Massive loss of comprehension happening, replaced by usually agreeable, "in-bubble" views - hence an actual loss of variety. So again, this isn’t to say non-commercial focused social media doesn’t have positive purposes, such as with activism at times. But, on the whole, it merely amplifies a general value system disorder of a “LOOK AT ME! LOOK AT HOW GREAT I AM!” – rooted in systemic insecurity. People lying to themselves, drawing meaningless satisfaction from superficial responses from a sea of avatars. And it’s no surprise. Market economics demands people self promote shamelessly, coupled with the arbitrary constructs of beauty and success that have also resulted. People see status in certain things and, directly or pathologically, use those things for their own narcissistic advantage. Think of those endless status pics of people rock climbing, or hanging out on a stunning beach or showing off their new trophy girl-friend, etc. It goes on and on and worse the general public generally likes it, seeking to imitate those images/symbols to amplify their own false status. Hence the endless feedback loop of superficiality. And people wonder why youth suicides have risen… a young woman looking at a model of perfection set by her peers, without proper knowledge of the medium, can be made to feel inferior far more dramatically than the typical body image problems associated to traditional advertising. That is just one example of the cultural violence inherent. The entire industry of social media is BASED on narcissistic status promotion and narrow self-interest. That is the emotion/intent that creates the billions and billions in revenue these platforms experience, as they in turn sell off people’s personal data to advertisers and governments. You are the product, of course.