Diagnostic Lab Quotes

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THE BUCCAL CELL SMEAR TEST (EXATest) Using cells gently scraped from an area in the mouth between the bottom teeth and the back of the tongue provides an accurate means of measuring the amount of magnesium in the cells of the body. Measuring cellular magnesium in this way indicates the amount of magnesium in heart and muscle cells, the two major body tissues affected by magnesium deficiency. The buccal cell smear test can be used to sample many things in cells; however, IntraCellular Diagnostics has developed a testing procedure called EXATest specifically to identify the amounts of certain minerals in the cell. The company sends sampling kits to your doctor’s office, where a simple procedure, which takes about 60 seconds, is performed. Your doctor uses a wooden spatula to scrape off superficial layers of cells under your tongue. The scrapings are carefully placed on a microscope slide and sent back to the lab. A special electron microscope then measures the amount of magnesium and other minerals in the sample on the slide. The results are sent back to your doctor. The test is expensive but may be covered by Medicare and insurance.
Carolyn Dean (The Magnesium Miracle (Revised and Updated))
There's nothing wrong with me. This has been medically proven, once. My former insurance company stopped honoring my requests for more diagnostics and labs. A therapist gave me medicine but I didn't take it because she didn't even run tests. She based her diagnosis on my answers, on the things I told her, and I bullshitted so much I couldn't even remember which parts were genuine. How could I take a pill based on that? And what if it worked? What if my bullshit was the right-sized hole for a pill-shaped fix? I felt helpless in the face of someone helping me.
Julia Dixon Evans (How to Set Yourself on Fire)
Co-founder of Gather Labs, Blaine Graboyes helped build a concierge wellness boutique and diagnostic lab.
Blaine Graboyes
it is not uncommon for experts in DNA analysis to testify at a criminal trial that a DNA sample taken from a crime scene matches that taken from a suspect. How certain are such matches? When DNA evidence was first introduced, a number of experts testified that false positives are impossible in DNA testing. Today DNA experts regularly testify that the odds of a random person’s matching the crime sample are less than 1 in 1 million or 1 in 1 billion. With those odds one could hardly blame a juror for thinking, throw away the key. But there is another statistic that is often not presented to the jury, one having to do with the fact that labs make errors, for instance, in collecting or handling a sample, by accidentally mixing or swapping samples, or by misinterpreting or incorrectly reporting results. Each of these errors is rare but not nearly as rare as a random match. The Philadelphia City Crime Laboratory, for instance, admitted that it had swapped the reference sample of the defendant and the victim in a rape case, and a testing firm called Cellmark Diagnostics admitted a similar error.20 Unfortunately, the power of statistics relating to DNA presented in court is such that in Oklahoma a court sentenced a man named Timothy Durham to more than 3,100 years in prison even though eleven witnesses had placed him in another state at the time of the crime. It turned out that in the initial analysis the lab had failed to completely separate the DNA of the rapist and that of the victim in the fluid they tested, and the combination of the victim’s and the rapist’s DNA produced a positive result when compared with Durham’s. A later retest turned up the error, and Durham was released after spending nearly four years in prison.21 Estimates of the error rate due to human causes vary, but many experts put it at around 1 percent. However, since the error rate of many labs has never been measured, courts often do not allow testimony on this overall statistic. Even if courts did allow testimony regarding false positives, how would jurors assess it? Most jurors assume that given the two types of error—the 1 in 1 billion accidental match and the 1 in 100 lab-error match—the overall error rate must be somewhere in between, say 1 in 500 million, which is still for most jurors beyond a reasonable doubt. But employing the laws of probability, we find a much different answer. The way to think of it is this: Since both errors are very unlikely, we can ignore the possibility that there is both an accidental match and a lab error. Therefore, we seek the probability that one error or the other occurred. That is given by our sum rule: it is the probability of a lab error (1 in 100) + the probability of an accidental match (1 in 1 billion). Since the latter is 10 million times smaller than the former, to a very good approximation the chance of both errors is the same as the chance of the more probable error—that is, the chances are 1 in 100. Given both possible causes, therefore, we should ignore the fancy expert testimony about the odds of accidental matches and focus instead on the much higher laboratory error rate—the very data courts often do not allow attorneys to present! And so the oft-repeated claims of DNA infallibility are exaggerated.
Leonard Mlodinow (The Drunkard's Walk: How Randomness Rules Our Lives)
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