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In 1999 the RAND Corporation published a report (the first and, so far, last of its kind) with a “conservative estimate” that more than 307 million tissue samples from more than 178 million people were stored in the United States alone. This number, the report said, was increasing by more than 20 million samples each year. The samples come from routine medical procedures, tests, operations, clinical trials, and research donations. They sit in lab freezers, on shelves, or in industrial vats of liquid nitrogen. They’re stored at military facilities, the FBI, and the National Institutes of Health.
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Rebecca Skloot (The Immortal Life of Henrietta Lacks)
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For me, hands are hard." She looks up from what she's doing. "Because you're holding this disconnected hand, and it's holding you back." Cadavers occasionally effect a sort of accidental humanness that catches the medical professional off guard. I once spoke to an anatomy student who described a moment in the lab when she realized that the cadaver's arm was around her waist. It becomes difficult, under circumstances such as these, to retain one's clinical remove.
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Mary Roach (Stiff: The Curious Lives of Human Cadavers)
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When pro-lifers buy into the lie that one child is more valuable and worthy of protection than another because it is further along or happens to be a product of a violent and inexcusable sexual act, then we are condoning the violent slaughter of children and, like the people working in POC labs across the country, we have the blood of innocents on our hands. Abortion
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Abby Johnson (The Walls Are Talking: Former Abortion Clinic Workers Tell Their Stories)
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Once I started seeing the college clinic psychiatrist, he pulled out my blood and showed me what was really in it, glanced at each trace mineral in the lab results, each lurking marker, but his eyes were focused on the good stuff, the chemicals he'd put there. I don't know if I believe in "Indian blood," but at times, I have wished I could test positive for it when the phlebotomist pulled my blood every month, checking to make sure my lithium levels aren't high enough to pickle my kidneys. Instead, the doctor only ever reads off results that sound like the bottom of a deep quarry, as though my body collects stones.
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Elissa Washuta (My Body Is a Book of Rules)
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A clinic in Bolivia 140 kilometers from the nearest city prints out splints and prostheses when supplies are low. The cost per piece runs about 2 cents for the plastic. This might allow developing nations to circumvent having to import large numbers of supplies. Already, 3D printing is occurring in underdeveloped areas. “Not Impossible Labs” based in Venice, California took 3D printers to Sudan where the chaos of war has left many people with amputated limbs. The organization’s founder, Mick Ebeling, trained locals how to operate the machinery, create patient–specific limbs, and fit these new, very inexpensive prosthetics.
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Bertalan Meskó (The Guide to the Future of Medicine (2022 Edition): Technology AND The Human Touch)
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WHY ADDICTION IS NOT A DISEASE In its present-day form, the disease model of addiction asserts that addiction is a chronic, relapsing brain disease. This disease is evidenced by changes in the brain, especially alterations in the striatum, brought about by the repeated uptake of dopamine in response to drugs and other substances. But it’s also shown by changes in the prefrontal cortex, where regions responsible for cognitive control become partially disconnected from the striatum and sometimes lose a portion of their synapses as the addiction progresses. These are big changes. They can’t be brushed aside. And the disease model is the only coherent model of addiction that actually pays attention to the brain changes reported by hundreds of labs in thousands of scientific articles. It certainly explains the neurobiology of addiction better than the “choice” model and other contenders. It may also have some real clinical utility. It makes sense of the helplessness addicts feel and encourages them to expiate their guilt and shame, by validating their belief that they are unable to get better by themselves. And it seems to account for the incredible persistence of addiction, its proneness to relapse. It even demonstrates why “choice” cannot be the whole answer, because choice is governed by motivation, which is governed by dopamine, and the dopamine system is presumably diseased. Then why should we reject the disease model? The main reason is this: Every experience that is repeated enough times because of its motivational appeal will change the wiring of the striatum (and related regions) while adjusting the flow and uptake of dopamine. Yet we wouldn’t want to call the excitement we feel when visiting Paris, meeting a lover, or cheering for our favourite team a disease. Each rewarding experience builds its own network of synapses in and around the striatum (and OFC), and those networks continue to draw dopamine from its reservoir in the midbrain. That’s true of Paris, romance, football, and heroin. As we anticipate and live through these experiences, each network of synapses is strengthened and refined, so the uptake of dopamine gets more selective as rewards are identified and habits established. Prefrontal control is not usually studied when it comes to travel arrangements and football, but we know from the laboratory and from real life that attractive goals frequently override self-restraint. We know that ego fatigue and now appeal, both natural processes, reduce coordination between prefrontal control systems and the motivational core of the brain (as I’ve called it). So even though addictive habits can be more deeply entrenched than many other habits, there is no clear dividing line between addiction and the repeated pursuit of other attractive goals, either in experience or in brain function. London just doesn’t do it for you anymore. It’s got to be Paris. Good food, sex, music . . . they no longer turn your crank. But cocaine sure does.
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Marc Lewis (The Biology of Desire: Why Addiction Is Not a Disease)
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intensive care units (ICUs) are physiologically fragile and unstable, generally have life-threatening conditions, and require close monitoring and rapid therapeutic interventions. They are connected to an array of equipment and monitors, and are carefully attended by the clinical staff. Staggering amounts of data are collected daily on each patient in an ICU: multi-channel waveform data sampled hundreds of times each second, vital sign time series updated each second or minute, alarms and alerts, lab results, imaging results, records of medication and fluid administration, staff notes and more.
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Mit Critical Data (Secondary Analysis of Electronic Health Records)
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A doctor in a white lab coat got up and introduced herself. She said her name was Susan or Stacey or Samantha and she was a fellow in the Clinical Research program. She read all the usual disclaimers and warnings, and reminded us that compensation would be issued in the form of Amazon gift cards, not checks or cash. A couple people grumbled, but I didn’t care; I had a boyfriend who bought gift cards off me for eighty cents on the dollar, so I was all set.
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Jason Rekulak (Hidden Pictures)
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International Air Transport Association (IATA) requires that all individuals responsible for shipping biological lab samples must be IATA certified, similar to GCP certification. Monitors do not typically ask for the IATA certifications of people at the site; however, it is mandatory that people in charge of shipping be certified. Non-compliance with IATA
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Dan Sfera (The Comprehensive Guide To Clinical Research: A Practical Handbook For Gaining Insight Into The Clinical Research Industry)
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In total, Leo and June rescued nearly two hundred colleagues from the Nazis while providing clinics, hospitals, and research labs across the country with an influx of superbly trained talent.
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Steve Silberman (NeuroTribes: The Legacy of Autism and the Future of Neurodiversity)
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You need to have a diploma from nursing school and be certified as a registered nurse. Ideally, you should have at least two to three years of clinical experience as an outpatient nurse or as an emergency room nurse. You should be certified in Basic Life Support and Advanced Cardiac Life Support (ACLS). Some cruise lines request Advanced Trauma Life Support (ATLS) certification as well. You may need to have experience in dealing with laboratory procedures and basic x-ray procedures as there is not likely to be a lab tech or x-ray tech on duty. You should have a background in general medicine and/or emergency medicine. You should have past experience caring for patients in a trauma, cardiac care, emergency care, or internal medicine practice. Because cruise liners travel to often to foreign lands and have people of all different cultures on board, you may need to have knowledge of other languages besides English. As
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Chase Hassen (Nursing Careers: Easily Choose What Nursing Career Will Make Your 12 Hour Shift a Blast! (Registered Nurse, Certified Nursing Assistant, Licensed Practical ... Nursing Scrubs, Nurse Anesthetist Book 1))
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IVF training courses IIRRH:
With more and more couples looking out for infertility treatment, the need for skilled fertility specialists has taken a huge leap in the recent years. Our IVF training courses at IIRRH are carefully structured to cater the needs of a beginner as well as a busy practitioner in the field of embryology, gynaecology and infertility management.
IIRRH offers courses that provide an avenue for both scientists and clinicians to enter the field of reproductive medicine; and for those already familiar with this area, an opportunity to gain greater skillset relevant to the manipulation of fertility and the treatment of reproductive abnormalities. Designed to broaden knowledge of the underlying scientific principles and to enhance appreciation of the clinical management of infertility, the institute aims to encourage independent thought and a research orientated approach to the practice of assisted conception.
Designed to broaden knowledge in the field of reproductive medicine and ART, our specialized courses include IVF training programs that cater the needs of a beginner as well as a busy practitioner in the field of embryology, gynaecology and infertility management. Our special Advanced ART course for Clinicians is apt to provide an introductory-level understanding of the clinical IVF (in-vitro fertilisation) laboratory and setting up and IVF lab.
As well as the basics of the IVF lab, it also covers:
• The individual protocols and procedures within the lab
• The requirements that must be considered when working within it
• Information ranging from embryo selection to new technologies in IVF
It will allow better practice and understanding in dealing with patients and IVF cases.
With the increasing demand for answers about our fertility, this course will help you understand:
• The role of the clinical embryologist
• Procedures conducted within the IVF laboratory
For more information visit our website iirrh.org
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IIRRH
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one of FerroKin’s most important solutions to the cost problem is to have no physical office, instead relying on wireless phones and home internet connections to coordinate an intensive round of pre-clinical investigations and regulatory filings. “We wanted to do this from our homes,” he says, because putting a premium on being in the same physical location every day and attending endless meetings unnecessarily constrains whom you can hire and what work skills you pay for in an employee. Sensitive medical information can be secured digitally even as it is shared among distributed team members and the outsourced labs and clinics that are performing the work. As a result, digital reduces the barriers to focusing on the job at hand.
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James McQuivey (Digital Disruption: Unleashing the Next Wave of Innovation)
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Established in 2018, Roseway Labs broadens access to compounded meds, offering tailored solutions for various medical needs. Our range includes compounded and licensed meds, supplements, diagnostic kits, and clinical stock. We specialise in hormones, thyroid, dermatology, hair loss, functional medicine, LDN, Lyme disease, pain management, allergies, intolerances, nutrition, and general medication. Our expertise ensures optimal results for prescribers and patients, prioritising personalised care and patient well-being. As a trusted healthcare partner, we provide compassionate and reliable solutions for unique medical needs.
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Roseway Labs
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The obvious solution is stem cells and, while they’re not ready for the clinic yet, “thymus organoids”—small, artificial thymuses grown in the lab—have been shown to work when transplanted into mice without thymuses, and rapid progress is being made in generating thymuses from iPSCs, too.
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Andrew Steele (Ageless: The New Science of Getting Older Without Getting Old)
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Readers of these pages will learn how in exalting patented medicine Dr. Fauci has, throughout his long career, routinely falsified science, deceived the public and physicians, and lied about safety and efficacy. Dr. Fauci’s malefactions detailed in this volume include his crimes against the hundreds of Black and Hispanic orphan and foster children whom he subjected to cruel and deadly medical experiments and his role, with Bill Gates, in transforming hundreds of thousands of Africans into lab rats for low-cost clinical trials of dangerous experimental drugs that, once approved, remain financially out of reach for most Africans. You will learn how Dr. Fauci and Mr. Gates have turned the African continent into a dumping ground for expired, dangerous, and ineffective drugs, many of them discontinued for safety reasons in the US and Europe.
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Robert F. Kennedy Jr. (The Real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health)
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Likewise, in men a careful assessment of clinical symptoms, physical examination, lifestyle factors, and biochemical lab data are all necessary not only to determine if you are a candidate for HOT with true testosterone deficiency, but also to rule out any important red flags that would require a deeper investigation and may lead to alternative therapeutic options.
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Tony Robbins (Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love)
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It is true that vaccines have in the past taken a long, long time to develop. Until 2020, a new vaccine usually took at least ten years to develop from concept to roll-out. Many took much longer. The malaria vaccine programme at the Jenner Institute has been going for twenty-five years, and research into malaria vaccines had been going on for more than a hundred years – so far, with limited success. The lab-to-jab record-holder was the mumps vaccine, developed in four years by Maurice Hilleman in the United States in the 1960s.1 But the standard lengthy timeline we were all used to was never because vaccine development required ten, fifteen or thirty years of continuous painstaking lab work, clinical trials and data analysis. For every vaccine that had ever been developed up until 2020, most of the elapsed development time was spent waiting. In 2020, there were three key factors that enabled us to cut out the waiting and crunch ten years into one: first, the work we had already done; second, changes to the way funding was given out; and third, doing in parallel things that we would normally do in sequence.
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Sarah Gilbert (Vaxxers: A Pioneering Moment in Scientific History)
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trial and error. Other experimenters recorded the visual fields of target subjects exposed to the color red. Trainees who learned, through feedback, to approximate that same neural activity reported seeing red in their mind’s eye. Since those days, the field had shifted from visual learning to emotional conditioning. The big grant money was going to desensitizing people with PTSD. DecNef and Connectivity Feedback were being touted as treatments to all kinds of psychiatric disorders. Marty Currier worked on clinical applications. But he was also pursuing a more exotic side-hustle. “Why not?” I told my wife. And so we volunteered in her friend’s experiment. IN THE RECEPTION AREA OF CURRIER’S LAB, Aly and I chuckled over the entrance questionnaire. We would be among the second wave of target subjects, but first we had to pass the screening. The questions disguised furtive motives. HOW OFTEN DO YOU THINK ABOUT THE PAST? WOULD YOU RATHER BE ON A CROWDED BEACH OR IN AN EMPTY MUSEUM? My wife shook her head at these crude inquiries and touched a hand to her smile. I read the expression as clearly as if we were wired up together: The investigators were welcome to anything they discovered inside her, so long as it didn’t lead to jail time. I’d given up on understanding my own hidden temperament a long time ago. Lots of monsters inhabited my sunless depths, but most of them were nonlethal. I did badly want to see my wife’s answers, but a lab tech prevented us from comparing questionnaires. DO YOU USE TOBACCO? Not for years. I didn’t mention that all my pencils were covered with bite marks. HOW MUCH ALCOHOL DO YOU DRINK A WEEK? Nothing for me, but my wife confessed to her nightly Happy Hour, while plying the dog with poetry. DO YOU SUFFER FROM ANY ALLERGIES? Not unless you counted cocktail parties. HAVE YOU EVER EXPERIENCED DEPRESSION? I didn’t know how to answer that one. DO YOU PLAY A MUSICAL INSTRUMENT? Science. I said I might be able to find middle C on a piano, if they needed it. Two postdocs took us into the fMRI room. These people had way more cash to throw around than any astrobiology team anywhere. Aly was having the same thoughts
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Richard Powers (Bewilderment)
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Dr. Amen Dhyllon, a pioneer in dentistry, is committed to pushing the boundaries of oral healthcare. With a wealth of experience and a passion for innovation, he's constantly seeking new ways to improve patient outcomes. As a member of various professional associations and with a track record of research awards, his expertise is widely recognized. When he's not in the clinic or the lab, he finds joy in the rhythm of his runs and the beauty of artistic expression.
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Amen Dhyllon
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After the active ingredients are manufactured, the additional ingredients chosen, and the principal laboratory and clinical tests conducted, the formula then moves to the manufacturing floor to see if it can be made on a commercial scale. As the manufacturing runs become larger, the processes become harder to control. If something can go wrong, it will. You can build a fortress of current good manufacturing practices around the drug-making process and still “shit happens,” as Malik liked to say. Conscientious manufacturers try to protect against past disasters and prevent new ones. But because manufacturing plants are operated by humans, the systems will break down, no matter how perfectly designed they are. For example, Johnson & Johnson’s epilepsy drug was fine until the company stacked it on wooden pallets that likely leached solvents into the medicine. At Mylan’s Morgantown plant, one lab technician left a note for another stating that he had to “rig” a hose on the equipment to get it to work properly—a word choice that easily could have shut down the plant had an FDA investigator stumbled across it and suspected fraud instead of primitive problem-solving. The only remedy for this variability is for plants to adhere scrupulously to good manufacturing practices and create real-time records of each drug-making step. The resulting data serve as a blueprint for finding and fixing the inevitable errors, a process that FDA investigators scrutinize. How well and how closely did the company investigate itself? The goal is to address a problem “in a way that it never happens again,” as Malik explained.
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Katherine Eban (Bottle of Lies: The Inside Story of the Generic Drug Boom)
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There’s actually lots of ways to “infect” a rat with depression, though some are more efficient than others. A frequently cited 1992 paper2 reviewing the best methods concludes that you don’t actually want to traumatize or terrify your rats, like Selye accidentally did. The closest approximation of the depression that plagues modern humans can be achieved by bombarding lab rats with mild but chronic, random, and inescapable stress. You don’t have to terrify them—just remove predictability and control from their lives, and they’ll eventually lose interest in pleasurable things. When they do, you’re ready to test whether your experimental antidepressant will get them interested again. “Losing interest in pleasure” so perfectly described my own gray years that it was kind of surreal to read it in the sterile, clinical context of a scientific paper about rats. I found the characterization of the best stressors as “mild” to be oddly affecting, too—I put off going to a doctor much longer than I should have because I didn’t think I’d really “earned” the right to have PTSD or depression, a feeling that’s apparently very common. I wasn’t a soldier or a refugee—nothing that bad had happened to me. But trauma isn’t the best method of creating a model of depression. All you have to do is remove control and predictability—the exact things low-wage workers have been forced to sacrifice in the name of corporate efficiency and flexibility. Is it any surprise that it feels like the country’s losing its collective mind? It would be more surprising if we weren’t.
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Emily Guendelsberger (On the Clock: What Low-Wage Work Did to Me and How It Drives America Insane)
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In 1963, Choh Hao Li, chairman and lone tenured faculty member in the Institute of Experimental Biology at Berkeley, announced that he had isolated and purified his sixth pituitary hormone, lipotropin. The magnitude of such a feat is clear considering that only one other person had ever purified a hormone, and that person was not coincidentally a student of Li's. The purification of lipotropin should have been a reason to celebrate; however, Li's colleagues at Berkeley acknowledged but did not rejoice in his success. As they perceived it, endocrinology was a scientific field that came out of the clinical sciences, which meant that Li's research was completely unsound, and they put enormous pressure on him to change his scientific topic. When that did not work, Wendell Stanley tried to 'promote [Li] out of the Virus Laboratory,' then later University Chancellor Clark Kerr threatened to discontinue the Institute for Experimental Biology because it did not fit with Berkeley's commitment to pure research. Things got infinitely worse for Li, of course, because he became perceived as less qualified with each professional achievement. [...]
C. H. Li's travails at Berkeley are only half the story. In 1969, five years after transferring from Berkeley to UCSF, Li and his laboratory assistants assembled a highly complex synthetic version of human growth hormone (HGH) that was biologically active and could promote the growth of bones and muscle tissue. Rather than ignore or criticize the work, however, journalists waxed eloquently [sic] about Li's creation of HGH. One described it as no less than a panacea for most of the world's problems. Others clearly saw specific applications: 'it might now be . . . possible to tailor-make hormones that can inhibit breast cancer.' Li's discovery of synthetic HGH 'constituted a truly . . . great research breakthrough [that had] obvious applications,' ranging from 'human growth and development to . . . treatment of cancer and coronary artery disease.' Desperate letters poured in too; athletes wanted to know if HGH would help them become faster, bigger, stronger, and dwarfs from all over the world begged for samples of HGH or to volunteer as experimental subjects. Unlike at Berkeley, Li's discovery made him a hero at UCSF. None other than UCSF Chancellor Phillip Lee described Li's discovery as 'meticulous, painstaking, and brilliant research' and then tried to capitalize on the moment by asking the public and their political representatives to increase federal support of bioscience research. 'Research money is dwindling fast,' repeated Lee to anyone who cared to listen. 'We've proven than synthesis can be done, now all we need is the money and time to prove its tremendous value.' It is not surprising that federal and state money began to pour into Li's lab. What is shocking, however, is how quickly Li achieved scientific acclaim, not because he changed, but because the rest of the world around him changed so much.
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Eric J. Vettel (Biotech: The Countercultural Origins of an Industry (Politics and Culture in Modern America))
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Until a vaccine is developed, sickness and death will continue. An unprecedented amount of research for a cure for the virus has resulted in promising new treatments. A couple of clinical labs are touting the possible availability by the fall of 2020 for these treatments. However, treatments only increase the survival rate and will not prevent people from contracting the virus.
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Earl Bristow (Revelation and Daniel Reveal How and When the World Ends (End of World Series Book 4))
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We have one of the best labs in the country, and that is one of the reasons why we are the best and exceptional in research. Clinic for those suffering from asthma and allergy conditions.
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Asthma And Allergy Clinic
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Though there're minor side effects in male adults."
"What side effect?"
She cocked an eyebrow and lowered her voice. "Spontaneous prolonged erection, big guy...in some test subjects," she added clinically. "A lot of those early tests were done on gorillas...
"I'm not a gorilla."
She glanced down the front of his lab coat. "Not yet.
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Ophelia London (Kissing Her Crush (Sugar City, #2))