Chemical Imbalance Quotes

I can tell you that “Just cheer up” is almost universally looked at as the most unhelpful depression cure ever. It’s pretty much the equivalent of telling someone who just had their legs amputated to “just walk it off.” Some people don’t understand that for a lot of us, mental illness is a severe chemical imbalance rather just having “a case of the Mondays.” Those same well-meaning people will tell me that I’m keeping myself from recovering because I really “just need to cheer up and smile.” That’s when I consider chopping off their arms and then blaming them for not picking up their severed arms so they can take them to the hospital to get reattached.

but it would be nice to say It’s raining only on my head rather than I have a chemical imbalance in my brain or I just remembered that someone I love will die before I do.

...love is a chemical imbalance, too. That perilous highs and desperate lows and extravagant flurries of mood are not always symptoms of a broken mind, but signs of a beating heart.

God judges men from the inside out; men judge men from the outside in. Perhaps to God, an extreme mental patient is doing quite well in going a month without murder, for he fought his chemical imbalance and succeeded; oppositely, perhaps the healthy, able and stable man who has never murdered in his life yet went a lifetime consciously, willingly never loving anyone but himself may then be subject to harsher judgment than the extreme mental patient. It might be so that God will stand for the weak and question the strong.

You know.” My voice was laced with sarcasm. “I love being reminded of just how f*cked up people find my company. One minute, I’m asked to be more loving and sweet. In fact, someone once told me it was downright adorable. But when I actually give the public what they want, they think I’m suffering from a chemical imbalance.

What does despair mean to someone who interprets that emotion as a chemical reaction in the brain?

Try yoga! Think about the good stuff! Keep yourself engaged! It’s all in your mind! Duh! It is! But is more of a chemical imbalance! I don’t know why people don’t take mental ailments as normal. People are accepting of AIDS, cancer, tuberculosis, etc. But mental ailments? They are just all in the mind!

Depression is not caused by a chemical imbalance in the brain, and it is not cured by medication. Depression may not even be an illness at all. Often, it can be a normal reaction to abnormal situations. Poverty, unemployment, and the loss of loved ones can make people depressed, and these social and situational causes of depression cannot be changed by drugs.

The rule of thumb is that if someone is able to be verbally or physically abusive, he or she is able to understand that the behavior is wrong.

Trust me, this whole freakout is probably just hormonal. You only gave birth, what, a week ago? Your body's still, like, a wasteland of chemical imbalance.

Rather than fix chemical imbalances in the brain, the drugs creat them.

Do I have an original thought in my head? My bald head. Maybe if I were happier, my hair wouldn't be falling out. Life is short. I need to make the most of it. Today is the first day of the rest of my life. I'm a walking cliché. I really need to go to the doctor and have my leg checked. There's something wrong. A bump. The dentist called again. I'm way overdue. If I stop putting things off, I would be happier. All I do is sit on my fat ass. If my ass wasn't fat I would be happier. I wouldn't have to wear these shirts with the tails out all the time. Like that's fooling anyone. Fat ass. I should start jogging again. Five miles a day. Really do it this time. Maybe rock climbing. I need to turn my life around. What do I need to do? I need to fall in love. I need to have a girlfriend. I need to read more, improve myself. What if I learned Russian or something? Or took up an instrument? I could speak Chinese. I'd be the screenwriter who speaks Chinese and plays the oboe. That would be cool. I should get my hair cut short. Stop trying to fool myself and everyone else into thinking I have a full head of hair. How pathetic is that? Just be real. Confident. Isn't that what women are attracted to? Men don't have to be attractive. But that's not true. Especially these days. Almost as much pressure on men as there is on women these days. Why should I be made to feel I have to apologize for my existence? Maybe it's my brain chemistry. Maybe that's what's wrong with me. Bad chemistry. All my problems and anxiety can be reduced to a chemical imbalance or some kind of misfiring synapses. I need to get help for that. But I'll still be ugly though. Nothing's gonna change that.

You are not a commodity. Your depression and anxiety are not just chemical imbalances in your brain but reasonable responses to a system that thrives on your dehumanization.

Despite what many modern educators would say, this is not a psychological disturbance brought on by violent television or chemical imbalance. Aggression is part of the masculine design; we are hardwired for it.

You can talk about depression as a "chemical imbalance" all you want, but it presents itself as an external antagonist - a "demon," a "beast," or a "black dog," as Samuel Johnson called it. It could pounce at any time, even in the most innocuous setting.

Happiness is a temporary chemical imbalance of the true state of mind.

Prior to being medicated, a depressed person has no known chemical imbalance.

You see, people in the depressive position are often stigmatised as ‘failures' or ‘losers'. Of course, nothing could be further from the truth. If these people are in the depressive position, it is most probably because they have tried too hard or taken on too much, so hard and so much that they have made themselves ‘ill with depression'. In other words, if these people are in the depressive position, it is because their world was simply not good enough for them. They wanted more, they wanted better, and they wanted different, not just for themselves, but for all those around them. So if they are failures or losers, this is only because they set the bar far too high. They could have swept everything under the carpet and pretended, as many people do, that all is for the best in the best of possible worlds. But unlike many people, they had the honesty and the strength to admit that something was amiss, that something was not quite right. So rather than being failures or losers, they are just the opposite: they are ambitious, they are truthful, and they are courageous. And that is precisely why they got ‘ill'. To make them believe that they are suffering from some chemical imbalance in the brain and that their recovery depends solely or even mostly on popping pills is to do them a great disfavour: it is to deny them the precious opportunity not only to identify and address important life problems, but also to develop a deeper and more refined appreciation of themselves and of the world around them—and therefore to deny them the opportunity to fulfil their highest potential as human beings.

A life out of balance is a person that doesn’t believe happiness can be achieved now, or in the future. It is as fleeting as the wind.

naturally, we are all caught in downmoods, it's a matter of chemical imbalance and an existence which, at times, seems to forbid any real chance at happiness.

I believe happiness is a chemical imbalance––it's a silly thing to strive for. But, satisfaction––if you seek satisfaction you can succeed.

I became a student of my own depressed experience, trying to unthread its causes. What was the root of all this despair? Was it psychological? (Was it Mom and Dad's fault?( Was it just temporal, a 'bad time' in my life? (When the divorce ends will the depression end with it?) Was it genetic? (Melancholy, called by many names, has run through my family for generations, along with its sad bride, Alcoholism.) Was it cultural? (Is this just the fallout of postfeminist American career girl trying to find balance in an increasingly stressful alienting urban world?) Was it astrological? (Am I so sad because I'm a thin-skinned Cancer whose major signs are all ruled by unstable Gemini?) Was it artistic? (Don't creative people always suffer from depression because we're so supersensitive and special?) Was it evolutionary? (Do I carry in me the residual panic that comes after millennia of my species' attempting to survive a brutal world?) Was it karmic? (Are all these spasms of grief just the consequences of bad behavior in previous lifetimes, the last obstacles before liberation?) Was it hormonal? Dietary? Philosophical? Seasonal? Environmental? Was I tapping into a universal yearning for God? Did I have a chemical imbalance? Or did I just need to get laid?

And what science had revealed was this: Prior to treatment, patients diagnosed with schizophrenia, depression, and other psychiatric disorders do not suffer from any known "chemical imbalance". However, once a person is put on a psychiatric medication, which, in one manner or another, throws a wrench into the usual mechanics of a neuronal pathway, his or her brain begins to function, as Hyman observed, abnormally.

The supposed reality of misfiring synapses, chemical imbalances, frontal lobe anomalies and the like - did not sway her desire for escape into an alternate universe - where she could discover fascinating things about her inner world - or where she could hide from the real world.

You have a chemical imbalance, that is all. If you were a diabetic, would you be ashamed

I think you have a chemical imbalance in your brain that inhibits your ability to assess your surroundings. This same defect is common in clowns. Mimes, also. And politicians. You all live in an altered sense of reality.

The primary explanation for depression offered in our culture starts to fall apart. The idea you feel terrible because of a “chemical imbalance” was built on a series of mistakes and errors. It has come as close to being proved wrong, he told me, as you ever get in science. It’s lying broken on the floor, like a neurochemical Humpty Dumpty with a very sad smile.

Chemically, I'm as off as I can be. But you fix me.

A significant number of people diagnosed with mental illness have psychic abilities not yet under control. They may have true mental illness as well, including faulty neurological wiring and chemical imbalance. However, some people have mental breaks because of psychic abilities they don’t know how to handle.

Anyone who is truly crazy, in my book, wouldn't be able to understand the dialectic of crazy and not-crazy. Listen, I've worked for the pharmaceutical companies, they have a vested belief in making you believe that if you have a chemical imbalance you need them to be 'cured' of your current issues and personality. Indefinitely. Imagine diagnosing personality only in terms of its negative aspects. Does this strike you as a strategy designed for health? The only way to deal with a problem is to fucking deal with it. Get inside what positive motivation, what intention, makes you behave in the way you are... and how you could maybe satisfy that need in a healthier or at least more agreeable manner. America wants quick, easy and painless; being a real person is slow, difficult and very messy.

Whether the underlying cause of your dependency is a chemical imbalance, unresolved events from the past, beliefs you hold that are inconsistent with what is true, an inability to cope with current conditions, or a combination of these four causes, know this: not only are all the causes of dependency within you, but all the solutions are within you as well.

NPD is not a chemical imbalance. And it is not genetic. It is a complex of behaviors, a deeply ingrained habit.

Was I tapping into a universal yearning for God? Did I have a chemical imbalance? Or did I just need to get laid?

Depression, we are told over and over again, is a brain disease, a chemical imbalance that can be adjusted by antidepressant medication. In an informational brochure issued to inform the public about depression, the US National Institute for Mental Health tells people that 'depressive illnesses are disorders of the brain' and adds that 'important neurotransmitters - chemicals that brain cells use to communicate - appear to be out of balance'. This view is so widespread that it was even proffered by the editors of PLoS [Public Library of Science] Medicine in their summary that accompanied our article. 'Depression,' they wrote, 'is a serious medical illness caused by imbalances in the brain chemicals that regulate mood', and they went on to say that antidepressants are supposed to work by correcting these imbalances. The editors wrote their comment on chemical imbalances as if it were an established fact, and this is also how it is presented by drug companies. Actually, it is not. Instead, even its proponents have to admit that it is a controversial hypothesis that has not yet been proven. Not only is the chemical-imbalance hypothesis unproven, but I will argue that it is about as close as a theory gets in science to being dis-proven by the evidence.

I took on my depression like it was the fight of my life, wich of course, it was. I became a student of my own depressed experience, trying to unthread its causes. What was the root of all this dispair? Was it psychological? (Mom and Dad's fault?) Was it just temporal, a "bad time" in my life? (When the divorce ends, will the depression end with it?) Was it genetic? (Melancholy, called by many names, has run through my family for generations, along with its sad bride, Alcholisme.) Was it cultural? (Is this just the fallout of a postfeminist American career girl trying to find balance in an increasingly stressful and alienating urban world?) Was it astrological? (Am I so sad because I'm a thin-skinned cancer whose major signs are all ruled by unstable Gemini?) Was it artistic? (Don't creative people always suffer from depression because we're so supersensitive and special?) Was it evolutionary? (Do I carry in me the residual panic that come after millennia of my species' attempting to survive a brutal world?) Was it Karmic? (Are all these spasms of grief just the consequences of bad behavior in previous lifetimes, the last obstacles before liberation?) Was it hormonal? Dietary? Philosophical? Seasonal? Environmental? Did I have a chemical imbalance? Or did I just need to get laid?

For the past twenty-five years, the psychiatric establishment has told us a false story. It told us that schizophrenia, depression, and bipolar illness are known to be brain diseases, even though—as the MindFreedom hunger strike revealed—it can’t direct us to any scientific studies that document this claim. It told us that psychiatric medications fix chemical imbalances in the brain, even though decades of research failed to find this to be so. It told us that Prozac and the other second-generation psychotropics were much better and safer than the first-generation drugs, even though the clinical studies had shown no such thing. Most important of all, the psychiatric establishment failed to tell us that the drugs worsen long-term outcomes.

It was around this time that a psychiatrist diagnosed me with both depression and ADD. Though there was no doubt I was depressed, I refused to take the pills that he prescribed, instead throwing them away. I knew then that my utter misery and universal disinterest were not due to a chemical imbalance. This wasn’t something that could just be medicated out of me—I just hated where I was.

Whenever I start to doubt if I’m worth the eternal trouble of medication and therapy, I remember those people who let the fog win. And I push myself to stay healthy. I remind myself that I’m not fighting against me … I’m fighting against a chemical imbalance … a tangible thing. I remind myself of the cunning untrustworthiness of the brain, both in the mentally ill and in the mentally stable.

But it turns out that dopamine is a chemical on double duty in the brain. Along with its role in motor commands, it also serves as the main messenger in the reward systems, guiding a person toward food, drink, mates, and all things useful for survival. Because of its role in the reward system, imbalances in dopamine can trigger gambling, overeating, and drug addiction—behaviors that result from a reward system gone awry.

I know Dad killed himself because of me. Mom thinks that his recent jail stint tipped him over the edge, that his many chemical imbalances caught up with him. Now I keep searching for happiness so I don’t end up like he did. I learn about this town called Happy in Texas and think about how that must be the greatest place to live. I teach myself how to say and read and write happy in Spanish, German, Italian, and even Japanese but I would have to draw that last one out. I discover the happiest animal in the world, the quokka. He’s a cheeky little bastard that’s always smiling. But it’s not enough. The memories are still rattling around my head, twisting into me like a knife. I don’t want to wait around to see what comes next for me in this tragic story I’m living. I open up one of my father’s unused razors and cut into my wrist like he did, slit in a curve until it smiles so everyone will know I died for happiness. I was expecting relief but instead it’s the saddest pain I’ve ever experienced. I never once stop feeling empty or unworthy of anyone’s rescue, not even when the thin line on my wrist makes everything go red. I

neurochemically, obsessive-compulsive disorder bears a conspicuous resemblance to falling in love. Scientists have scanned the brains of the pathologically obsessive and held them up next to brain scans of the love-struck, and the images turned colors in the same places. Doctors drew blood and found the same chemical imbalances—namely, a serotonin deficit.

Throughout the human life span there remains a constant two-way interaction between psychological states and the neurochemistry of the frontal lobes, a fact that many doctors do not pay enough attention to. One result is the overreliance on medications in the treatment of mental disorders. Modern psychiatry is doing too much listening to Prozac and not enough listening to human beings; people’s life histories should be given at least as much importance as the chemistry of their brains. The dominant tendency is to explain mental conditions by deficiencies of the brain’s chemical messengers, the neurotransmitters. As Daniel J. Siegel has sharply remarked, “We hear it said everywhere these days that the experience of human beings comes from their chemicals.” Depression, according to the simple biochemical model, is due to a lack of serotonin — and, it is said, so is excessive aggression. The answer is Prozac, which increases serotonin levels in the brain. Attention deficit is thought to be due in part to an undersupply of dopamine, one of the brain’s most important neurotransmitters, crucial to attention and to experiencing reward states. The answer is Ritalin. Just as Prozac elevates serotonin levels, Ritalin or other psychostimulants are thought to increase the availability of dopamine in the brain’s prefrontal areas. This is believed to increase motivation and attention by improving the functioning of areas in the prefrontal cortex. Although they carry some truth, such biochemical explanations of complex mental states are dangerous oversimplifications — as the neurologist Antonio Damasio cautions: "When it comes to explaining behavior and mind, it is not enough to mention neurochemistry... The problem is that it is not the absence or low amount of serotonin per se that “causes” certain manifestations. Serotonin is part of an exceedingly complicated mechanism which operates at the level of molecules, synapses, local circuits, and systems, and in which sociocultural factors, past and present, also intervene powerfully. The deficiencies and imbalances of brain chemicals are as much effect as cause. They are greatly influenced by emotional experiences. Some experiences deplete the supply of neurotransmitters; other experiences enhance them. In turn, the availability — or lack of availability — of brain chemicals can promote certain behaviors and emotional responses and inhibit others. Once more we see that the relationship between behavior and biology is not a one-way street.

Antidepressants fail to outperform placebos in up to half of clinical trials. Armed with fMRI technology, brain scientists now understand that assuming we are born with chemical imbalances is putting the chicken before the egg—trauma changes the structure and chemical and hormonal responses of our brains. In many cases, we can’t just pump opposing chemicals into our brains with the assumption that things will change. We have to treat the underlying, original cause: the trauma.

Every so often people make mistakes; it’s biological, a result of the same kind of chemical and hormonal imbalances that occasionally lead to Unnaturalism, to boys being attracted to boys and girls to girls. These impulses, too, will be resolved by the cure.

Although the idea has been around for ages, most depressed people do not really comprehend it. If you feel depressed, you may think it is because of bad things that have happened to you. You may think you are inferior and destined to be unhappy because you failed in your work or were rejected by someone you loved. You may think your feelings of inadequacy result from some personal defect—you may feel convinced you are not smart enough, successful enough, attractive enough, or talented enough to feel happy and fulfilled. You may think your negative feelings are the result of an unloving or traumatic childhood, or bad genes you inherited, or a chemical or hormonal imbalance of some type. Or you may blame others when you get upset: “It’s these lousy stupid drivers that tick me off when I drive to work! If it weren’t for these jerks, I’d be having a perfect day!” And nearly all depressed people are convinced that they are facing some special, awful truth about themselves and the world and that their terrible feelings are absolutely realistic and inevitable. Certainly all these ideas contain an important gem of truth—bad things do happen, and life beats up on most of us at times. Many people do experience catastrophic losses and confront devastating personal problems. Our genes, hormones, and childhood experiences probably do have an impact on how we think and feel. And other people can be annoying, cruel, or thoughtless. But all these theories about the causes of our bad moods have the tendency to make us victims—because we think the causes result from something beyond our control. After all, there is little we can do to change the way people drive at rush hour, or the way we were treated when we were young, or our genes or body chemistry (save taking a pill). In contrast, you can learn to change the way you think about things, and you can also change your basic values and beliefs. And when you do, you will often experience profound and lasting changes in your mood, outlook, and productivity. That, in a nutshell, is what cognitive therapy is all about. The theory is straightforward

I have spent years ... clinging to the understanding that I was a defective biological unit .... This may truly be a valuable perspective for those who observe mental illness, but for me, as a subject, this tree bore only dry and tasteless fruit ... I have a chemical imbalance; I really didn't feel those things. I have a chemical imbalance; I didn't really experience those things. I have a chemical imbalance; I didn't really think those things ... Here is an insight! The entire human drama of love, suffering, ecstasy, and joy, just chemistry.

All this to say, ADHD isn’t your fault. You aren’t selfish, reckless, or irresponsible by nature. Most people seem to have a double standard for chemical imbalances in the brain, as opposed to elsewhere in the body. One would not — we hope! — tell a person with Type I Diabetes to try harder because everyone’s blood sugar gets out of whack sometimes. We’d expect this person to maintain their condition with insulin and a healthy diet so they could live a normal life. Why would we expect someone with a chemical imbalance in the brain to correct it by sheer force of will when we don’t expect them to do it with their pancreas? The sooner you accept your ADHD as a part of your unique biology, not as a personal failing, the sooner you can begin to build a better life for yourself

Such experiences can act even on the unborn child. A recent study found that, at one year of age, the infants of women traumatized during their pregnancies by the 9/11 tragedy had abnormal blood levels of the stress hormone, cortisol.2 According to numerous human and animal studies, adverse early experiences may lead to permanent imbalances of essential brain chemicals that modulate mood and behavior.

The results of decades of neurotransmitter-depletion studies point to one inescapable conclusion: low levels or serotonin, norepinephrine or dopamine do not cause depression. here is how the authors of the most complete meta-analysis of serotonin-depletion studies summarized the data: "Although previously the monoamine systems were considered to be responsible for the development of major depressive disorder (MDD), the available evidence to date does not support a direct causal relationship with MDD. There is no simple direct correlation of serotonin or norepinephrine levels in the brain and mood.' In other words, after a half-century of research, the chemical-imbalance hypothesis as promulgated by the drug companies that manufacture SSRIs and other antidepressants is not only with clear and consistent support, but has been disproved by experimental evidence.

He seems so drugged up and slow. I miss his laughter, his impulsiveness, his wacky sense of humour, even his obsessive practicing. It makes me wonder who he actually is. If the old Flynn was ill – courtesy of a chemical imbalance in the brain – is this lithiumed Flynn the real MyCoy? Or perhaps both characters are just facets of a hidden, deeper soul that I have yet to meet. I just don’t know. Sometimes I fear that the drug-free Flynn searingly manic, then catastrophically depressed – is who he really is. But because in that form he is not acceptable to conventional society, he has to be drugged so that his emotions are tempered and his behavior controlled. Perhaps we are blindly living in an Orwellian society where individualism is feared and the biggest pressure is the one to conform. Perhaps Flynn is sane and the rest of the world is mad. The thoughts go round and round in my head.

With the rise of molecular genetics, it has become possible to search for possible changes (mutations, polymorphisms) in target genes. Much effort has gone into investigating variations in genes that contribute to serotonin transmission, because serotonin-related drugs have antidepressant and anxiolytic properties. This assumes, however, that the treatment mechanism is the same mechanism that gives rise to the disorder.53 Although this is consistent with the old chemical imbalance hypothesis, it is not a conclusion that should simply be accepted without careful assessment. Nevertheless, studies of the genetic control of serotonin have found interesting results. For example, people with a certain variant (polymorphism) of a gene controlling a protein involved in serotonin transmission are more reactive to threatening stimuli, and this hyperreactivity is associated with increased amygdala activity during the threat.54 Further, it has been reported that this variant of the gene can account for 7 percent to 9 percent of the inheritance of anxiety.55

if there is no proof that a depressed person has a chemical imbalance, and you choose nevertheless to put that person on a medication that will alter neurotransmitter levels in his or her brain, then in effect you are causing a chemical imbalance rather than curing one. According to Steven Hyman, a neuroscientist and former director of the National Institute of Mental Health, all psychotropic drugs cause “perturbations in neurotransmitter functions.” And this is Whitaker’s main point. We are subjecting millions of brains to drugs that change natural neurotransmission, sometimes radically, disturbing and upsetting the complex interplay inside our heads, clogging neural pathways with excess chemicals, and sometimes causing the entire brain, which is intricately interlinked, to malfunction in ways we do not yet understand. An unmedicated depressed patient does not have a known chemical imbalance in his brain, but once he ingests Prozac, he will. The drug crosses the blood-brain barrier and gets to work, jamming serotonin into the synaptic cleft. Whitaker explains the result this way: “Several weeks later the serotonergic pathway is operating in a decidedly abnormal manner.

There's a lot of wealth in the world. For the most part in Western society, we've removed the threat of starvation an other life and death issues. Everything should be rosy. But it's not. As I've already noted, there is a rise in the incidence of depression in the Western world that threatens to become an epidemic. Freudian psychology says, 'Analyze them and find out what went wrong in their upbringing, then find a solution and fix them.' Other scientists look at the chemicals in the brain and say, 'Aha, it seems that they are depressed because they do not have enough x. Give them this pill and they will be fine in an hour or so.' That sort of thinking is like fixing a machine. Find out what's wrong, make the repairs and put it back into service. If it's human, analyze it, decide what's wrong, put it back into the economic machine, keep it going, keep it desiring, keep it working to fulfill it's desires. When it does it will be happy. NO. Doesn't work. I know people who have been taking antidepressant medication for years. There's nothing wrong with taking medication to correct an imbalance. The problem occurs if that's all you do. You need to take action to move things forward and change who you are being.

We can all intellectually understand that the brain can manage and regulate many diverse functions throughout the rest of the body, but how responsible are we for the job our brain is doing as CEO of the body? Whether we like it or not, once a thought happens in the brain, the rest is history. All of the bodily reactions that occur from both our intentional or unintentional thinking unfold behind the scenes of our awareness. When you come right down to it, it is startling to realize how influential and extensive the effects of one or two conscious or unconscious thoughts can be. For example, is it possible that the seemingly unconscious thoughts that run through our mind daily and repeatedly create a cascade of chemical reactions that produce not only what we feel but also how we feel? Can we accept that the long-term effects of our habitual thinking just might be the cause of how our body moves to a state of imbalance, or what we call disease? Is it likely, moment by moment, that we train our body to be unhealthy by our repeated thoughts and reactions? What if just by thinking, we cause our internal chemistry to be bumped out of normal range so often that the body’s self-regulation system eventually redefines these abnormal states as normal, regular states? It’s a subtle process, but maybe we just never gave it that much attention until now.

You can't fix a chemical imbalance with positive thinking.

Depression is endemic. It is the condition most dealt with by the National Health Service, and is afflicting people at increasingly younger ages. The number of students who have some variant of dyslexia is astonishing. It is not an exaggeration to say that being a teenager in late capitalist Britain is now close to being reclassified as a sickness. This pathologization already forecloses any possibility of politicization. By privatizing these problems – treating them as if they were caused only by chemical imbalances in the individual’s neurology and/or by their family background – any question of social systemic causation is ruled out.

Due to commercials and the “education” of prescribers directly by pharmaceutical representatives, the idea that people who were sad and depressed had chemical imbalances in their brains became common parlance. So how is this an example of manufacturing a disease? There is no such thing as a chemical imbalance that is known to cause some identifiable disease called depression. In fact, leaders within psychiatry have called the chemical imbalance theory an “urban legend” that was never taken seriously by “well-informed psychiatrists” (Pies, 2011). An entire society was led to believe in a disease known to be caused by neurochemical imbalances as a direct result of a genius marketing scheme, and nothing more (see also Schultz & Hunter, 2016 for a review).

9 We were antonyms The chemical imbalance An erupted Yellowstone Creek volcano We were lost in translation Our bodies equally in contemplation This has to be it The myriad form of intoxication. The Metaphor of Metamorphosis 10 A glacial naked body "A poetic equivalent of representation Governed in your mind as an option of versatility I was only one of your many drafts How naïve of me to think that this, this was love at first sight.

We were antonyms The chemical imbalance An erupted Yellowstone Creek volcano We were lost in translation Our bodies are equally in contemplation This has to be it The myriad forms of intoxication.

I think that passion might be a chemical imbalance.

The public was being told two clashing things. First, that the symptoms of depression are straightforwardly the result of a chemical imbalance in the brain that has to be fixed with drugs. Second, that somehow, and at the same time, there was one unique situation where all the symptoms of depression were, in fact, a response to something terrible happening in your life, and in that one unique case, a chemical imbalance is not the cause, and drugs are not the solution.

I WANT TO USE THIS SO YOU UNDERSTAND THAT MOST OF THE TIME YOUR ANGER IS STUPID CHEMICAL HORMONE IMBALANCE IN YOUR SYSTEM. DO NOT RESPECT YOUR ANGER, MOOD SWINGS, DELUSIONS MORE THAN JUST CHEMICAL HORMONAL IMBALANCES.

Prior to treatment, patients diagnosed with schizophrenia, depression, and other psychiatric disorders do not suffer from any known “chemical imbalance.” However, once a person is put on a psychiatric medication, which, in one manner or another, throws a wrench into the usual mechanics of a neuronal pathway, his or her brain begins to function, as Hyman observed, abnormally.

Today, as provost of Harvard University, Steve Hyman is mostly engaged in the many political and administrative tasks that come with leading a large institution. But he is a neuroscientist by training, and in 1996 to 2001, when he was the director of the NIMH, he wrote a paper, one both memorable and provocative in kind, that summed up all that had been learned about psychiatric drugs. Titled “Initiation and Adaptation: A Paradigm for Understanding Psychotropic Drug Action,” it was published in the American Journal of Psychiatry, and it told of how all psychotropic drugs could be understood to act on the brain in a common way.46 Antipsychotics, antidepressants, and other psychotropic drugs, he wrote, “create perturbations in neurotransmitter functions.” In response, the brain goes through a series of compensatory adaptations. If a drug blocks a neurotransmitter (as an antipsychotic does), the presynaptic neurons spring into hyper gear and release more of it, and the postsynaptic neurons increase the density of their receptors for that chemical messenger. Conversely, if a drug increases the synaptic levels of a neurotransmitter (as an antidepressant does), it provokes the opposite response: The presynaptic neurons decrease their firing rates and the postsynaptic neurons decrease the density of their receptors for the neurotransmitter. In each instance, the brain is trying to nullify the drug’s effects. “These adaptations,” Hyman explained, “are rooted in homeostatic mechanisms that exist, presumably, to permit cells to maintain their equilibrium in the face of alterations in the environment or changes in the internal milieu.” However, after a period of time, these compensatory mechanisms break down. The “chronic administration” of the drug then causes “substantial and long-lasting alterations in neural function,” Hyman wrote. As part of this long-term adaptation process, there are changes in intracellular signaling pathways and gene expression. After a few weeks, he concluded, the person’s brain is functioning in a manner that is “qualitatively as well as quantitatively different from the normal state.” His was an elegant paper, and it summed up what had been learned from decades of impressive scientific work. Forty years earlier, when Thorazine and the other first-generation psychiatric drugs were discovered, scientists had little understanding of how neurons communicated with one another. Now they had a remarkably detailed understanding of neurotransmitter systems in the brain and of how drugs acted on them. And what science had revealed was this: Prior to treatment, patients diagnosed with schizophrenia, depression, and other psychiatric disorders do not suffer from any known “chemical imbalance.” However, once a person is put on a psychiatric medication, which, in one manner or another, throws a wrench into the usual mechanics of a neuronal pathway, his or her brain begins to function, as Hyman observed, abnormally.

in believing that anxiety disorders typically arise from failed efforts to resolve basic existential dilemmas, Dr. W. is, as we will see, running against the grain of modern psychopharmacology (which proffers the evidence of sixty years of drug studies to argue that anxiety and depression are based on “chemical imbalances”), neuroscience (whose emergence has demonstrated not only the brain activity associated with various emotional states but also, in some cases, the specific structural abnormalities associated with mental illness), and temperament studies and molecular genetics (which suggest, rather convincingly, a powerful role for heredity in the determination of one’s baseline level of anxiety and susceptibility to psychiatric illness). Dr. W. doesn’t dispute the findings from any of those modes of inquiry. He believes medication can be an effective treatment for the symptoms of anxiety. But his view, based on thirty years of clinical work with hundreds of anxious patients, is that at the root of almost all clinical anxiety is some kind of existential crisis about what he calls the “ontological givens”—that we will grow old, that we will die, that we will lose people we love, that we will likely endure identity-shaking professional failures and personal humiliations, that we must struggle to find meaning and purpose in our lives, and that we must make trade-offs between personal freedom and emotional security and between our desires and the constraints of our relationships and our communities. In this view, our phobias of rats or snakes or cheese or honey (yes, honey; the actor Richard Burton could not bear to be in a room with honey, even if it was sealed in a jar, even if the jar was closed in a drawer) are displacements of our deeper existential concerns projected onto outward things. Early

alcoholics believe they are a breed apart; they are not happy no matter what they have in life, and the only thing that can truly take away their misery is a drink. No matter what they have in life and no matter how happy they ought to be, they will be depressed because of the chemical imbalance caused by the drink.

My doctor says it’s a chemical imbalance in my brain, and fuck, they’re probably right. But it doesn’t stop the very real, un-chemical, raw nothingness that ravages my entire being.

That doesn’t mean all chemical antidepressants are bad: some credible scientists argue they give some temporary relief to a minority of users, and that shouldn’t be dismissed. The false story is the claim that depression is caused by a chemical imbalance in the brain and that the primary solution for most people is a chemical antidepressant. That story has made Big Pharma over $100 billion,1 which is one of the crucial reasons why it persists.

Love is a chemical imbalance. Good or bad, it's all a mental illness. And like any addiction, you keep going back after the bad because the good is just so damn good. Or you think it is at least. At the time.

While these reports did tell of a new drug that was superior to the old class of antidepressants, this still was not a narrative of a “breakthrough” medication. There was no sense of why this drug worked better, but as FDA approval for fluoxetine neared, a new “fact” began to appear in the scientific reports. In a 1987 article in the British Journal of Psychiatry, Sidney Levine wrote that “studies have shown that [serotonin] deficiency plays an important role in the psychobiology of depressive illness.”25 While this was not what had actually been found—Levine had apparently missed the 1984 NIMH report that “elevations or decrements in the functioning of serotonergic systems per se are not likely to be associated with depression”—this article set the stage for fluoxetine to be touted as a drug that fixed a chemical imbalance. Two years later, University of Louisville psychiatrists surveyed the fluoxetine literature in order to provide “prescribing guidelines for the newest antidepressant,” and they wrote that “depressed patients have lower than normal concentrations of [serotonin metabolites] in their cerebrospinal fluid.” A delusional belief was now spreading through the medical literature, and perhaps not surprisingly, the Kentucky psychiatrists concluded that fluoxetine, which theoretically raised serotonin levels, was “an ideal drug for the treatment of depression.”26

In "Shyness: How Normal Behavior Became a Sickness" (2007) Christopher Lane describes how pharmaceutical companies helped to persuade the American Psychiatric Association to include social phobia in the "DSM" of 1980. He argues that the diagnosis in many cases turned a personality trait into an illness, pathologising people who were resvered, private or quiet. 'Over the course of six years,' he writes, 'a small group of self-selecting American psychiatrists built a sweeping new consensus: shyness and a host of comparable traits were anxiety and personality disorders. And they stemmed not from psychological conflicts or social tensions, but rather from a chemical imbalance or faulty neurotransmitters in the brain.' Lane believes that there is a great cost to medicalising our quirks, eccentricities and ordinary feelings. "The sad consequence,' he says, 'is a vast, perhaps irrecoverable, loss of emotional range, an impovershment of human experience.

As we learned later, when your brain has a natural chemical imbalance, putting more chemicals on top of it? Not so great. Weed made the mania manifest faster and more aggressively (which I would come to be thankful for, a chapter for later).

Understanding low mood as a useful response and depression as excessive low mood suggests different approaches to treatment. Depression is caused by the situation, the view of the situation, and the brain. Treatment can change the situation, the view of the situation, and the brain. However, all three interact in tangled webs of causes, so addressing only one of them will miss many treatment possibilities. This view has implications for understanding how antidepressants work. The idea that they normalize a “chemical imbalance” is appealing and helps to justify drug treatment, but there is no evidence for any specific chemical abnormality specific to depression. It seems more likely that antidepressants do for psychic pain what analgesics do for physical pain: they disrupt a normal response system. People have wondered how antidepressants with effects on different brain chemicals all can be effective. There is no mystery here. Aspirin, acetaminophen, ibuprofen, and morphine all act on somewhat different links in the pain regulation mechanism. Different antidepressants act on different links in the mood regulation system. The analogy goes further. Our strategies for relieving psychic pain are about as effective as our strategies for relieving physical pain—modestly to moderately effective, usually with side effects, often with risks on withdrawal, but still an enormous boon to humankind.

Ben, schizophrenia alone disables more people for a longer time than cancer. Hundreds of thousands of people are confined to hospitals. We can’t turn our backs on them or burn them as witches because of a chemical imbalance in the brain.” He

When you are depressed, you have a chemical imbalance in your brain. Thoughts trigger emotions, which dump an overload of stress chemicals into the brain. There is a chemical consequence in the brain for every thought we think. Depression can be short-circuited temporarily by the brain-switching process. It’s a way of restoring the chemical balance. The thoughts that create depression connect with one’s memory banks, which have emotional associations. In

They are merely actors, playing roles in complex dramas and intrigues to remain forever, they suppose, fictional.

That doesn’t mean all chemical antidepressants are bad: some credible scientists argue they give some temporary relief to a minority of users, and that shouldn’t be dismissed. The false story is the claim that depression is caused by a chemical imbalance in the brain and that the primary solution for most people is a chemical antidepressant.

The United Nations—in its official statement for World Health Day in 2017—explained3 that “the dominant biomedical narrative of depression” is based on “biased and selective use of research outcomes” that “cause more harm than good, undermine the right to health, and must be abandoned.” There is a “growing evidence base,” they state, that there are deeper causes of depression, so while there is some role for medications, we need to stop using them “to address issues which are closely related to social problems.” We need to move from “focusing on ‘chemical imbalances’ to focusing on ‘power imbalances.

Whether people are besieged by a chemical imbalance or thrown into a panic or depression by a wrenching loss, their inconsistencies also belong to the self.

Personally, I believe that love is merely a chemical imbalance that makes you forget your credit card limit.

It’s a well-known fact that God makes green-eyed men for one purpose only: to remind me that love is a chemical imbalance, too. That perilous highs and desperate lows and extravagant flurries of mood are not always symptoms of a broken mind, but signs of a beating heart. If

When you are depressed, you have a chemical imbalance in your brain. Thoughts trigger emotions, which dump an overload of stress chemicals into the brain. There is a chemical consequence in the brain for every thought we think. Depression can be short-circuited temporarily by the brain-switching process. It’s a way of restoring the chemical balance. The thoughts that create depression connect with one’s memory banks, which have emotional associations. In The Depression Cure, Ilardi writes: There’s evidence that depression can leave a toxic imprint on the brain. It can etch its way into our neural circuitry—including the brain’s stress response system—and make it much easier for the brain to fall back into another episode of depression down the road. This helps explain a puzzling fact: It normally takes a high level of life stress to trigger someone’s first episode of depression, but later relapse episodes sometimes come totally out of the blue. It seems that once the brain has learned how to operate in depression mode, it can find its way back there with much less prompting. Fortunately, though, we can heal from the damage of depression. All it takes is several months of complete recovery for much of the toxic imprint on the brain to be erased [or overridden].[88] In brainswitching, you choose a new thought that’s neutral or nonsense. This thought doesn’t

Grieving the Holy Spirit (Ephesians 4:30). Our anger grieves God’s Spirit, not only producing bitter fruit but quenching the fruit of the Spirit in our lives. Rather than operating with love, joy, and peace toward others, a bitter person becomes hateful, negative, and restless, closing off his heart toward others. Bitter people become very unlike themselves. The most loving and joyful people in the world can become hateful, irrational pessimists if they let bitterness take root and don’t forgive. Believe it or not, bitterness even hurts us physically. “A joyful heart is good medicine, but a broken spirit dries up the bones” (Proverbs 17:22). The tension of trying to contain it can harden our facial features and make us lose the radiance of our countenance, even causing a chemical imbalance in our bodies and lowering our resistance to disease.

It was clearly stated by Drs. Lacasse and Leo in their 2005 paper: “These advertisements present a seductive concept, and the fact that patients are now presenting with a self-described ‘chemical imbalance’ shows that the [advertising] is having its intended effect: the medical marketplace is being shaped in a way that is advantageous to the pharmaceutical companies.

People who kill themselves generally suffer from severe clinical depression,” I said. “Their reasons for choosing suicide are not always rational. It’s often a chemical imbalance that leads them to the choice.

Biological psychiatry was founded on, and still largely adheres to, the assumption that mental disorders are due to chemical imbalances in the brain. The brain, in this view, is like a delicate soup. To maintain its characteristic flavor, just the right mix of key ingredients is required. Too little or too much of one or another item, and its character is altered. But the normal character can sometimes be restored with the right mix of additional ingredients that either replace a missing ingredient or dampen the effects of an overly abundant one. Like a master chef's, the biological psychiatrist's job is to adjust the blend, to balance the chemistry, so that the desired character is restored.

Eating more than you need is not necessarily a sign of a chemical imbalance or eating the wrong types of food. It is a sign that you are fundamentally out of balance.

I have spent years ... clinging to the understanding that I was a defective biological unit .... This may truly be a valuable perspective for those who observe mental illness, but for me, as a subject, this tree bore only dry and tasteless fruit ...• I have a chemical imbalance; I really didn't feel those things. I have a chemical imbalance; I didn't really experience those things. I have a chemical imbalance; I didn't really think those things ... Here is an insight! The entire human drama of love, suffering, ecstasy, and joy, just chemistry.

Have you heard or been told that chemical imbalances occur in depression? If so, you have been seriously misinformed.

only sin that a wife will readily admit to is her negative reaction to her husband’s failure to be loving or for losing patience with the children. Beyond these areas, women do not see themselves as sinning, even though they readily admit bad habits and wrong attitudes. They write these off to chemical imbalance, hormonal problems, or dysfunction due to family of origin. For

Love is ridiculous, right? A chemical imbalance, an illness. We catch it, we go mad for a little while, and what do we do when it passes? if we're "lucky," we're saddled with an imperfect marriage, a mortgage, and obnoxious, needy, resentful kids. Our ambitions and dreams and potential greatness are extinguished for want of a little human contact and some orgasms (passing bodily contractions that can easily be achieved on one's own). And yet, 99% of all music, literature, film, and art is devoted to love. The world carries on like this is the best, most natural thing. We sing endless songs about getting sick, and the complex of scars left when the illness fades.

caused their insanity. That is why we can justify housing them in inhumane conditions and punishing rather than treating them. The federal government says mental illness is a chemical imbalance, and because of that it’s a sickness and not something, as Rachel Diaz said, that anyone seeks or wants or deserves to get any more than he seeks, wants, or deserves to get a cold.

If you poll people in the church, you will find a spectrum of opinions on psychiatric medication. Some will say it is from the Devil, some will say it is the answer, and some don't care. A more moderate opinion is that, although it is not wrong to take these medications, they are rarely our first line of attack against personal suffering. Instead, we should first consider that God can bless us through our suffering, and we might also weigh the possibility that psychiatric medications could numb us to the refining benefits of suffering. There is a worthwhile point here. Although it may sound strange or evening unloving to those who don't share a biblical position, there can be real benefits from having our faith testing a strengthened through trials. Consider it pure joy, my brothers, whenever you face trials of many kinds, because you know that the testing of your faith develops perseverance. Perseverance must finish its work so that you may be mature and complete, not lacking anything. (James 1:2-4) Suffering is not always something that must be escaped. In contrast to the growing American sentiment that we have a right to a pain-free existence, most everyone has personal examples of how suffering and difficulties have been essential to Christian maturity. Conversely, most everyone has witnessed the sad consequences of lives that have been artificially shielded from suffering by overprotective parents or illegal, mind-altering drugs. Given these common observations, suffering is not always the enemy that we think it is, and medication should not be considered the ultimate answer.

If you poll people in the church, you will find a spectrum of opinions on psychiatric medication. Some will say it is from the Devil, some will say it is the answer, and some don't care. A more moderate opinion is that, although it is not wrong to take these medications, they are rarely our first line of attack against personal suffering. Instead, we should first consider that God can bless us through our suffering, and we might also weigh the possibility that psychiatric medications could numb us to the refining benefits of suffering. There is a worthwhile point here. Although it may sound strange or even unloving to those who don't share a biblical position, there can be real benefits from having our faith testing a strengthened through trials. Consider it pure joy, my brothers, whenever you face trials of many kinds, because you know that the testing of your faith develops perseverance. Perseverance must finish its work so that you may be mature and complete, not lacking anything. (James 1:2-4) Suffering is not always something that must be escaped. In contrast to the growing American sentiment that we have a right to a pain-free existence, most everyone has personal examples of how suffering and difficulties have been essential to Christian maturity. Conversely, most everyone has witnessed the sad consequences of lives that have been artificially shielded from suffering by overprotective parents or illegal, mind-altering drugs. Given these common observations, suffering is not always the enemy that we think it is, and medication should not be considered the ultimate answer.

The “chemical imbalance” theory of depression, for example, also known as the catecholamine, monoamine, or serotonin deficiency hypothesis, was based on the chemical action of the first generation of antidepressants, which were discovered serendipitously and found to act on monoamine pathways to increase monoamine concentrations (López‐Muñoz & Alamo, 2009). We now know that the “chemical imbalance” hypothesis of depression is false. First, the fact that drugs that increase monoamine concentrations also reduce depressive symptoms (O'Donnell, 2011) is not strong evidence that depression is caused by a deficiency of monoamines. Aspirin reduces headache symptoms but headaches are not caused by an aspirin deficiency. Second, antidepressant drugs increase monoamine concentrations almost immediately (within minutes), but their antidepressant effects only appear after a few weeks (Frazer & Benmansour, 2002; Harmer, Goodwin, & Cowen, 2009). Third, other drugs, such as cocaine, increase monoamines (Kalsner & Nickerson, 1969; Kuhar, Ritz, & Boja, 1991) but are not effective antidepressants. Fourth, some antidepressant drugs, such as tianeptine, decrease monoamines (Baune & Renger, 2014; McEwen et al., 2010). Fifth, depletion of monoamines does not induce depression in non‐depressed individuals (Ruhé, Mason, & Schene, 2007). In summary, although monoamines might play some role in depression, there is no evidence that depression is caused by a simple imbalance of serotonin, norepinephrine, or any other neurotransmitter or biochemical (Kendler, 2008; Lacasse & Leo, 2015, and references therein).

We now know that the “chemical imbalance” hypothesis of depression is false... Aspirin reduces headache symptoms but headaches are not caused by an aspirin deficiency... treating symptoms is not necessarily equivalent to correcting a biological dysfunction.

But chemical imbalances don’t cause depression. Depression causes chemical imbalances.

The theories that patients with depression lack serotonin and that patients with schizophrenia have too much dopamine have long been refuted. The truth is just the opposite. There is no chemical imbalance to begin with, but when treating mental illness with drugs, we create a chemical imbalance.

What was love anyway, except a biological trick? It was larger doses of hormones like oxytocin and dopamine, which delivered a euphoric rush. It was lower levels of serotonin, which induced anxiety and made you focus obsessively on the object of your “love.” It was elevated levels of adrenaline and norepinephrine making your heart flutter and your palms sweat. She liked Joe and he liked her. The rest was a temporary chemical imbalance.

This is what work-life balance means. It has nothing to do with the hours we work or the stress we suffer. It has to do with where we feel safe. If we feel safe at home, but we don’t feel safe at work, then we will suffer what we perceive to be a work-life imbalance. If we have strong relationships at home and at work, if we feel like we belong, if we feel protected in both, then the powerful forces of a magical chemical like oxytocin can diminish the effect of stress and cortisol.