Cell Group Quotes

I speak and speak,” Marco says, “but the listener retains only the words he is expecting. The description of the world to which you lend a benevolent ear is one thing; the description that will go the rounds of the groups of stevedores and gondoliers on the street outside my house the day of my return is another; and yet another, that which I might dictate late in life, if I were taken prisoner by Genoese pirates and put in irons in the same cell with a writer of adventure stories. It is not the voice that commands the story: it is the ear.

I draw a line down the middle of a chalkboard, sketching a male symbol on one side and a female symbol on the other. Then I ask just the men: What steps do you guys take, on a daily basis, to prevent yourselves from being sexually assaulted? At first there is a kind of awkward silence as the men try to figure out if they've been asked a trick question. The silence gives way to a smattering of nervous laughter. Occasionally, a young a guy will raise his hand and say, 'I stay out of prison.' This is typically followed by another moment of laughter, before someone finally raises his hand and soberly states, 'Nothing. I don't think about it.' Then I ask women the same question. What steps do you take on a daily basis to prevent yourselves from being sexually assaulted? Women throughout the audience immediately start raising their hands. As the men sit in stunned silence, the women recount safety precautions they take as part of their daily routine. Here are some of their answers: Hold my keys as a potential weapon. Look in the back seat of the car before getting in. Carry a cell phone. Don't go jogging at night. Lock all the windows when I sleep, even on hot summer nights. Be careful not to drink too much. Don't put my drink down and come back to it; make sure I see it being poured. Own a big dog. Carry Mace or pepper spray. Have an unlisted phone number. Have a man's voice on my answering machine. Park in well-lit areas. Don't use parking garages. Don't get on elevators with only one man, or with a group of men. Vary my route home from work. Watch what I wear. Don't use highway rest areas. Use a home alarm system. Don't wear headphones when jogging. Avoid forests or wooded areas, even in the daytime. Don't take a first-floor apartment. Go out in groups. Own a firearm. Meet men on first dates in public places. Make sure to have a car or cab fare. Don't make eye contact with men on the street. Make assertive eye contact with men on the street.

Random mutations much more easily debilitate genes than improve them, and that this is true even of the helpful mutations. Let me emphasize, our experience with malaria’s effects on humans (arguably our most highly studied genetic system) shows that most helpful mutations degrade genes. What’s more, as a group the mutations are incoherent, meaning that they are not adding up to some new system. They are just small changes - mostly degradative - in pre-existing, unrelated genes. The take-home lesson is that this is certainly not the kind of process we would expect to build the astonishingly elegant machinery of the cell. If random mutation plus selective pressure substantially trashes the human genome, why should we think that it would be a constructive force in the long term? There is no reason to think so.

We’re not always selfish hypocrites. We also have the ability, under special circumstances, to shut down our petty selves and become like cells in a larger body, or like bees in a hive, working for the good of the group. These experiences are often among the most cherished of our lives, although our hivishness can blind us to other moral concerns. Our bee-like nature facilitates altruism, heroism, war, and genocide.

The transpersonal experiences revealing the Earth as an intelligent, conscious entity are corroborated by scientific evidence. Gregory Bateson, who created a brilliant synthesis of cybernetics, information and systems theory, the theory of evolution, anthropology, and psychology came to the conclusion that it was logically inevitable to assume that mental processes occurred at all levels in any system or natural phenomenon of sufficient complexity. He believed that mental processes are present in cells, organs, tissues, organisms, animal and human groups, eco-systems, and even the earth and universe as a whole.

the group of incest survivors had abnormalities in their CD45 RA-to-RO ratio, compared with their nontraumatized peers. CD45 cells are the “memory cells” of the immune system.

A few gasps sounded from the people watching this turn of events, but then Ian sidled up to the group. "Mine, mine, mine," he said as he collected cell phones from the onlookers, flashing his own mesmerizing gaze to still the instant protests. Now, at least we wouldn't have to worry about video of this ending up online.

Wherever something is wrong, something is too big. If the stars in the sky or the atoms of uranium disintegrate in spontaneous explosion, it is not because their substance has lost its balance. It is because matter has attempted to expand beyond the impassable barriers set to every accumulation. Their mass has become too big. If the human body becomes diseased, it is, as in cancer, because a cell, or a group of cells, has begun to outgrow its allotted narrow limits. And if the body of a people becomes diseased with the fever of aggression, brutzdity, collectivism, or massive idiocy, it is not because it has fallen victim to bad leadership or mental derangement. It is because huma beings, so charming as individuals or in small aggregations, have been welded into overconcentrated social units such as mobs, unions, cartels, or great powers.

The individual is a cell in the social superorganism. When he feels he is no longer necessary to the larger group, he, too, begins to wither away. As

At each step biochemical triggers and feedbacks determine which of the alternative developmental pathways among several possibles a group of cells will actually follow.

The Empire was crumbling every day. Trillions of people were free because of the Rebellion. Because she was a general running a battle group instead of a cell leader flying the Ghost on one mad assignment or another. Still, she missed her old crew. Her family. She wished they all could have been with her aboard the Lodestar.

Chemopreventive agents can be classified into different subgroups based on which stage of cancer development they help to fight: Carcinogen blockers and antioxidants help prevent the initial triggering DNA mutation, and antiproliferatives work by keeping tumors from growing and spreading. Curcumin is special in that it appears to belong to all three groups, meaning it may potentially help prevent and/or arrest cancer cell growth.13

I tried to be as inconspicuous as possible as I lay the sausage against my ear. Abruptly, my cell phone went dead. A drop of grease dribbled into the dead center of my ear, creeping like a worm down onto my neck and below the collar of my shirt. A group of men and women in business suits walked by, swerving to avoid me. Across the street, a homeless-looking guy was staring at me, curious. Yep, this was pretty much rock bottom. As I was about to reach for a napkin and at least get my money's worth by eating the bratwurst while still hot, I heard it. "Dave? Can you hear me?

Hate can be a deeply stimulating emotion. The world becomes easier to understand and much less terrifying if you divide everything and everyone into friends and enemies, we and they, good and evil. The easiest way to unite a group isn't through love, because love is hard, It makes demands. Hate is simple. So the first thing that happens in a conflict is that we choose a side, because that's easier than trying to hold two thoughts in our heads at the same time. The second thing that happens is that we seek out facts that confirm what we want to believe - comforting facts, ones that permit life to go on as normal. The third is that we dehumanize our enemy. There are many ways of doing that, but none is easier than taking her name away from her. So when night comes and the truths spread, no one types "Maya" on their cell phone or computer in Beartown, they type "M." Or "the young woman." Or "the slut." No one talks about "the rape," they all talk about "the allegation." Or "the lie." It starts with "nothing happened," moves on to "and if anything did happen, it was voluntary," escalates to "and if it wasn't voluntary, she only has herself to blame; what did she think was going to happen if she got drunk and went into his room with him?" It starts with "she wanted it" and ends with "she deserved it." It doesn't take long to persuade each other to stop seeing a person as a person. And when enough people are quiet for long enough, a handful of voices can give the impression that everyone is screaming.

They were all just countless cells that had joined together to make this group in particular—this group that Julie Jacobson, who had no currency whatsoever, suddenly decided she loved.

A neuron is a nerve cell that transmits information using electrical or chemical signals. A synapse is a structure or pathway that carries a signal from a neuron to another neuron or cell.

Many young people are leaving other churches, feeling that the sermons and the programs are not relevant to them. They say, “We’ll come back when we’re sixty years old and the sermons are relevant to us. Then we can prepare for heaven, because that’s all the ministers seem to be preaching about—getting ready for heaven. But we are living on earth now, and the message is unrelated to our lives.

Lorsque j’ai commencé à voyager en Gwendalavir aux côtés d'Ewìlan et de Salim, je savais que, au fil de mon écriture, ma route croiserait celle d'une multitude de personnages. Personnages attachants ou irritants, discrets ou hauts en couleurs, pertinents ou impertinents, sympathiques ou maléfiques... Je savais cela et je m'en réjouissais. Rien, en revanche, ne m'avait préparé à une rencontre qui allait bouleverser ma vie. Rien ne m'avait préparé à Ellana. Elle est arrivée dans la Quête à sa manière, tout en finesse tonitruante, en délicatesse remarquable, en discrétion étincelante. Elle est arrivée à un moment clef, elle qui se moque des serrures, à un moment charnière, elle qui se rit des portes, au sein d’un groupe constitué, elle pourtant pétrie d’indépendance, son caractère forgé au feu de la solitude. Elle est arrivée, s'est glissée dans la confiance d'Ewilan avec l'aisance d'un songe, a capté le regard d’Edwin et son respect, a séduit Salim, conquis maître Duom... Je l’ai regardée agir, admiratif ; sans me douter un instant de la toile que sa présence, son charisme, sa beauté tissaient autour de moi. Aucun calcul de sa part. Ellana vit, elle ne calcule pas. Elle s'est contentée d'être et, ce faisant, elle a tranquillement troqué son statut de personnage secondaire pour celui de figure emblématique d'une double trilogie qui ne portait pourtant pas son nom. Convaincue du pouvoir de l'ombre, elle n'a pas cherché la lumière, a épaulé Ewilan dans sa quête d'identité puis dans sa recherche d'une parade au danger qui menaçait l'Empire. Sans elle, Ewilan n'aurait pas retrouvé ses parents, sans elle, l'Empire aurait succombé à la soif de pouvoir des Valinguites, mais elle n’en a tiré aucune gloire, trop équilibrée pour ignorer que la victoire s'appuyait sur les épaules d'un groupe de compagnons soudés par une indéfectible amitié. Lorsque j'ai posé le dernier mot du dernier tome de la saga d'Ewilan, je pensais que chacun de ses compagnons avait mérité le repos. Que chacun d'eux allait suivre son chemin, chercher son bonheur, vivre sa vie de personnage libéré par l'auteur après une éprouvante aventure littéraire. Chacun ? Pas Ellana. Impossible de la quitter. Elle hante mes rêves, se promène dans mon quotidien, fluide et insaisissable, transforme ma vision des choses et ma perception des autres, crochète mes pensées intimes, escalade mes désirs secrets... Un auteur peut-il tomber amoureux de l'un de ses personnages ? Est-ce moi qui ai créé Ellana ou n'ai-je vraiment commencé à exister que le jour où elle est apparue ? Nos routes sont-elles liées à jamais ? — Il y a deux réponses à ces questions, souffle le vent à mon oreille. Comme à toutes les questions. Celle du savant et celle du poète. — Celle du savant ? Celle du poète ? Qu'est-ce que... — Chut... Écris.

This new science of performance argues that you get better at a skill as you develop more myelin around the relevant neurons, allowing the corresponding circuit to fire more effortlessly and effectively. To be great at something is to be well myelinated. This understanding is important because it provides a neurological foundation for why deliberate practice works. By focusing intensely on a specific skill, you’re forcing the specific relevant circuit to fire, again and again, in isolation. This repetitive use of a specific circuit triggers cells called oligodendrocytes to begin wrapping layers of myelin around the neurons in the circuits—effectively cementing the skill. The reason, therefore, why it’s important to focus intensely on the task at hand while avoiding distraction is because this is the only way to isolate the relevant neural circuit enough to trigger useful myelination. By contrast, if you’re trying to learn a complex new skill (say, SQL database management) in a state of low concentration (perhaps you also have your Facebook feed open), you’re firing too many circuits simultaneously and haphazardly to isolate the group of neurons you actually want to strengthen. In

Regardless of whether one subscribes to the aims of the four movements whose stories we have told, there is much to appreciate about them as movements. They have overcome schisms; disbandment; leadership scandals; and/or the deaths of their founders. They have developed a highly innovative strategy—bypassing the state—to overcome the obstacles that their ideological strictness; ambitious agendas; and reluctance to compromise present. They have shown a strong entrepreneurial spirit in building effective social service agencies, medical facilities, schools, and businesses that often put the state’s efforts to shame. While they are not the Christian militias, al-Qaeda cells, or Jewish extremist groups whose terrorism has attracted much attention, the Muslim Brotherhood, Shas, Comunione e Liberazione, and the Salvation Army, with their strategy of rebuilding society, one institution at a time, may well prove more successful in sacralizing their societies than movements that use violence.

Our visual field, the entire view of what we can see when we look out into the world, is divided into billions of tiny spots or pixels. Each pixel is filled with atoms and molecules that are in vibration. The retinal cells in the back of our eyes detect the movement of those atomic particles. Atoms vibrating at different frequencies emit different wavelengths of energy, and this information is eventually coded as different colors by the visual cortex in the occipital region of our brain. A visual image is built by our brain's ability to package groups of pixels together in the form of edges. Different edges with different orientations - vertical, horizontal and oblique, combine to form complex images. Different groups of cells in our brain add depth, color and motion to what we see.

We must be serious about church growth if we are concerned about the future of the Church of Jesus Christ. Church growth is not just another fad. Jesus came to build a Church, and that Church has been asleep until now. It is waking up! Any church that wakes up is going to grow.

A former student, in an essay called "The Paradox of Potential," writes, "Instead, we moved cautiously, in groups, plodding down a few well-worn trails so as to ensure that two or four years down the road, we could be stem cells again, still undifferentiated, still brimming with potential.

There's a reason they say nothing good ever came out of a committee. Beware of Focus Groups, Working Parties, Conference Calls, and people who find ninety-nine reasons to say no before they find a single reason to say yes. It's these people who are responsible for most of the evil in the universe.

Look, cell phone geolocation data shows very few clustering anomalies for this hour and climate. And that’s holding up pretty much across all major metro areas. It’s gone down six percentage points since news of the Karachi workshop hit the Web, and it’s trending downward. If people are protesting, they aren’t doing it in the streets.” He circled his finger over a few clusters of dots. “Some potential protest knots in Portland and Austin, but defiance-related tag cloud groupings in social media put us within the three-sigma rule—meaning roughly sixty-eight percent of the values lie within one standard deviation of the mean.

Pavlov formulated his findings into a general rule in which the speed of learning positively correlated with quiet isolation. The totalitarians have followed this rule. They know they can condition their political victims most quickly if they are kept in isolation. In the totalitarian technique of thought control, the same isolation applied to the individual is applied also to the groups of people. This is the reason the civilian populations of the totalitarian countries are not permitted to travel freely and are kept away from mental and political contamination. It is the reason, to, for the solitary confinement cell and the prison camp.

The FRG … was the closest thing any of them had to family, this simulacrum of friendship, women suddenly thrown together in a time of duress, with no one to depend on but each other, all of them bereft and left behind in this dry expanse of central Texas, walled in by strip malls, chain restaurants, and highways that led to better places. Most of them had gotten used to making life for themselves without a husband, finding doctors and dentists and playgrounds, filling their cell phones with numbers and their calendars with playdates, and then the husbands would return and the Army would toss them all at some other base in the middle of nowhere to begin again.

Chlamydia, today´s most common cause of venereal disease, does the equivalent of hiding in the police station. Schistosomes of the mansoni type go a step further and essentially steal police uniforms. These parasites, a serious cause of liver disease in Asia, pick up blood-group antigens so that they may look to the immune system like our own normal blood cells.

Opponents of abortion use the word baby to refer to the cluster of cells, the embryo, and the fetus alike. The very choice of the word baby imposes the idea of an independently existing human being. Whereas cluster of cells, embryo, and fetus keep discussion in the medical domain, baby moves the discussion to the moral domain. The issue of the morality of abortion is settled once the words are chosen. The purposeful removal of a cell group from the mother that does not constitute an independently existing, viable, or even a recognizable human being cannot be “murder.” The word “murder” is not defined as such a medical procedure. The purposeful killing of a “baby”—an independently existing human being—can be “murder.” Is

The case I’ve presented in this book suggests that humans are undergoing what biologists call a major transition. Such transitions occur when less complex forms of life combine in some way to give rise to more complex forms. Examples include the transition from independently replicating molecules to replicating packages called chromosomes or, the transition from different kinds of simple cells to more complex cells in which these once-distinct simple cell types came to perform critical functions and become entirely mutually interdependent, such as the nucleus and mitochondria in our own cells. Our species’ dependence on cumulative culture for survival, on living in cooperative groups, on alloparenting and a division of labor and information, and on our communicative repertoires mean that humans have begun to satisfy all the requirements for a major biological transition. Thus, we are literally the beginnings of a new kind of animal.1 By contrast, the wrong way to understand humans is to think that we are just a really smart, though somewhat less hairy, chimpanzee. This view is surprisingly common. Understanding how this major transition is occurring alters how we think about the origins of our species, about the reasons for our immense ecological success, and about the uniqueness of our place in nature. The insights generated alter our understandings of intelligence, faith, innovation, intergroup competition, cooperation, institutions, rituals, and the psychological differences between populations. Recognizing that we are a cultural species means that, even in the short run (when genes don’t have enough time to change), institutions, technologies, and languages are coevolving with psychological biases, cognitive abilities, emotional responses, and preferences. In the longer run, genes are evolving to adapt to these culturally constructed worlds, and this has been, and is now, the primary driver of human genetic evolution. Figure 17.1.

Serotonin, a brain neurotransmitter, is known to be low in some depressions; studies show that normal sunlight causes the body to release serotonin, which is one reason people living far from the equator feel rejuvenated and in a good mood on sunny holidays. Laser light also releases serotonin, as well as other important brain chemicals, such as endorphins, which lower pain, and acetylcholine, which is essential for learning—and which might help an injured brain relearn mental abilities that have been lost. Kahn, Naeser, and the Harvard group believe that laser light affects the cerebrospinal fluid as well. Kahn believes that the cerebral spinal fluid and the blood vessels carry the photons into the brain, where they influence the brain cells, as they might other cells. The scientific research on this pathway is in its infancy.

Inside the cells of neglected rat pups, enzymes attached chemical tags called methyl groups to their DNA. This mode of inheritance is called epigenetic, since the tags sit on the DNA, and the prefix epi-, from ancient Greek, means “upon.” It differs from the conventional, genetic mode of heredity because the tagged gene still carries the same information, and makes the same protein. But when it’s tagged, it has a hard time doing so.

I was about to beg Rhys to fly me home when I caught the strands of music pouring from a group of performers outside a restaurant. My hands slackened at my sides. A reduced version of the symphony I'd heard in a chill dungeon, when I had been so lost in terror and despair that I'd hallucinated- hallucinated as this music poured into my cell- and kept me from shattering. And once more, the beauty of it hit me, the layering and swaying, the joy and peace. They had never played a piece like it Under the Mountain- never this sort of music. And I'd never heard music in my cell save for that one time. 'You,' I breathed, not taking my eyes from the musicians playing so skilfully that even the diners had set down their forks in the cafe nearby. 'You sent that music into my cell. Why?' Rhysand's voice was hoarse. 'Because you were breaking. And I couldn't find another way to save you.

The problem with racial discrimination, though, is not the inference of a person's race from their genetic characteristics. It is quite the opposite: it is the inference of a person's characteristics from their race. The question is not, can you, given an individual's skin color, hair texture, or language, infer something about their ancestry or origin. That is a question of biological systematics -- of lineage, taxonomy, of racial geography, of biological discrimination. Of course you can -- and genomics as vastly refined that inference. You can scan any individual genome and infer rather deep insights about a person's ancestry, or place of origin. But the vastly more controversial question is the converse: Given a racial identity -- African or Asian, say -- can you infer anything about an individual's characteristics: not just skin or hair color, but more complex features, such as intelligence, habits, personality, and aptitude? /I/ Genes can certainly tell us about race, but can race tell us anything about genes? /i/ To answer this question, we need to measure how genetic variation is distributed across various racial categories. Is there more diversity _within_ races or _between_ races? Does knowing that someone is of African versus European descent, say, allow us to refine our understanding of their genetic traits, or their personal, physical, or intellectual attributes in a meaningful manner? Or is there so much variation within Africans and Europeans that _intraracial_ diversity dominates the comparison, thereby making the category "African" or "European" moot? We now know precise and quantitative answers to these questions. A number of studies have tried to quantify the level of genetic diversity of the human genome. The most recent estimates suggest that the vast proportion of genetic diversity (85 to 90 percent) occurs _within_ so-called races (i.e., within Asians or Africans) and only a minor proportion (7 percent) within racial groups (the geneticist Richard Lewontin had estimated a similar distribution as early as 1972). Some genes certainly vary sharply between racial or ethnic groups -- sickle-cell anemia is an Afro-Caribbean and Indian disease, and Tay-Sachs disease has a much higher frequency in Ashkenazi Jews -- but for the most part, the genetic diversity within any racial group dominates the diversity between racial groups -- not marginally, but by an enormous amount. The degree of interracial variability makes "race" a poor surrogate for nearly any feature: in a genetic sense, an African man from Nigria is so "different" from another man from Namibia that it makes little sense to lump them into the same category.

No one has been able to aggregate more intention data on what consumers like than Google. Google not only sees you coming, but sees where you’re going. When homicide investigators arrive at a crime scene and there is a suspect—almost always the spouse—they check the suspect’s search history for suspicious Google queries (like “how to poison your husband”). I suspect we’re going to find that U.S. agencies have been mining Google to understand the intentions of more than some shopper thinking about detergent, but cells looking for fertilizer to build bombs. Google controls a massive amount of behavioral data. However, the individual identities of users have to be anonymized and, to the best of our knowledge, grouped. People are not comfortable with their name and picture next to a list of all the things they have typed into the Google query box. And for good reasons. Take a moment to imagine your picture and your name above everything you have typed into that Google search box. You’ve no doubt typed in some crazy shit that you would rather other people not know. So, Google has to aggregate this data, and can only say that people of this age or people of this cohort, on average, type in these sorts of things into their Google search box. Google still has a massive amount of data it can connect, if not to specific identities, to specific groups.

The charge that Anarchism is destructive, rather than constructive, and that, therefore, Anarchism is opposed to organization, is one of the many falsehoods spread by our opponents. They confound our present social institutions with organization; hence they fail to understand how we can oppose the former, and yet favor the latter. The fact, however, is that the two are not identical. “The State is commonly regarded as the highest form of organization. But is it in reality a true organization? Is it not rather an arbitrary institution, cunningly imposed upon the masses? “Industry, too, is called an organization; yet nothing is farther from the truth. Industry is the ceaseless piracy of the rich against the poor. “We are asked to believe that the Army is an organization, but a close investigation will show that it is nothing else than a cruel instrument of blind force. “The Public School! The colleges and other institutions of learning, are they not models of organization, offering the people fine opportunities for instruction? Far from it. The school, more than any other institution, is a veritable barrack, where the human mind is drilled and manipulated into submission to various social and moral spooks, and thus fitted to continue our system of exploitation and oppression. “Organization, as WE understand it, however, is a different thing. It is based, primarily, on freedom. It is a natural and voluntary grouping of energies to secure results beneficial to humanity. “It is the harmony of organic growth which produces variety of color and form, the complete whole we admire in the flower. Analogously will the organized activity of free human beings, imbued with the spirit of solidarity, result in the perfection of social harmony, which we call Anarchism. In fact, Anarchism alone makes non-authoritarian organization of common interests possible, since it abolishes the existing antagonism between individuals and classes. “Under present conditions the antagonism of economic and social interests results in relentless war among the social units, and creates an insurmountable obstacle in the way of a co-operative commonwealth. “There is a mistaken notion that organization does not foster individual freedom; that, on the contrary, it means the decay of individuality. In reality, however, the true function of organization is to aid the development and growth of personality. “Just as the animal cells, by mutual co-operation, express their latent powers in formation of the complete organism, so does the individual, by co-operative effort with other individuals, attain his highest form of development. “An organization, in the true sense, cannot result from the combination of mere nonentities. It must be composed of self-conscious, intelligent individualities. Indeed, the total of the possibilities and activities of an organization is represented in the expression of individual energies. “It therefore logically follows that the greater the number of strong, self-conscious personalities in an organization, the less danger of stagnation, and the more intense its life element. “Anarchism asserts the possibility of an organization without discipline, fear, or punishment, and without the pressure of poverty: a new social organism which will make an end to the terrible struggle for the means of existence,—the savage struggle which undermines the finest qualities in man, and ever widens the social abyss. In short, Anarchism strives towards a social organization which will establish well-being for all. “The germ of such an organization can be found in that form of trades unionism which has done away with centralization, bureaucracy, and discipline, and which favors independent and direct action on the part of its members.

I don’t have custody. Wayne is just—We’re on good terms about our son. It’s not an issue.” “Got a number where we can reach him?” “Yes, but he’s on a plane right now. He visited for the Fourth. He’s headed back this evening.” “You sure about that? How do you know he boarded the plane?” “I’m sure he had nothing to do with this, if that’s what you’re asking. We’re not fighting over our son. My ex is the most harmless and easygoing man you’ve ever met.” “Oh, I don’t know. I’ve met some pretty easygoing fellas. I know a guy up in Maine who leads a Buddhist-themed therapy group, teaches people about managing their temper and addictions through Transcendental Meditation. The only time this guy ever lost his composure was the day his wife served him with a restraining order. First he lost his Zen, then he lost two bullets in the back of her head. But that Buddhist-themed therapy group he runs sure is popular on his cell block in Shawshank. Lotta guys with anger-management issues in there.

The Institute had explored the behavior of a great variety of complex systems—corporations in the marketplace, neurons in the human brain, enzyme cascades within a single cell, the group behavior of migratory birds—systems so complex that it had not been possible to study them before the advent of the computer. The research was new, and the findings were surprising. It did not take long before the scientists began to notice that complex systems showed certain common behaviors. They started to think of these behaviors as characteristic of all complex systems. They realized that these behaviors could not be explained by analyzing the components of the systems. The time-honored scientific approach of reductionism—taking the watch apart to see how it worked—didn’t get you anywhere with complex systems, because the interesting behavior seemed to arise from the spontaneous interaction of the components. The behavior wasn’t planned or directed; it just happened. Such behavior was therefore called “self-organizing.

The word epigenetics literally means “above the gene.” It refers to the control of genes not from within the DNA itself but from messages coming from outside the cell—in other words, from the environment. These signals cause a methyl group (one carbon atom attached to three hydrogen atoms) to attach to a specific spot on a gene, and this process (called DNA methylation) is one of the main processes that turns the gene off or on. (Two other processes, covalent histone modification and noncoding RNA, also turn genes on and off,

The unconscious brain apparently never forgets. Everything it has experienced is set somewhere in the 100 billion or so cells that make up our vast internal universe. But the way the mind works is that things that are repeated are strengthened, making stronger and more numerous synapses, so that the memory becomes more and more important to our overall patterns of thinking. We attach emotions to events to create memories. The more intense and more frequent an event is—as it strikes us—the more it looms large in our mental attic.

Depuis les réformes de la fin du XVIème siècle menées par Hideyoshi, on n'entre plus dans le groupe des samouraïs autrement que par la naissance. Le statut de guerrier se mue, et pour près de deux siècles et demi, s'apparente à l'une des formes de la noblesse, la noblesse militaire. Celle-ci était déjà fonctionnarisée : elle fut contrainte par les grands seigneurs (daimyos) à s'installer dans les villes au pied des chateaux où elle exercea des tâches d'encadrement et d'administration moyennant une compensation financière, un fief-rente.

We have not thoroughly assessed the bodies snatched from dirt and sand to be chained in a cell. We have not reckoned with the horrendous, violent mass kidnapping that we call the Middle Passage. We have not been honest about all of America's complicity - about the wealth the South earned on the backs of the enslaved, or the wealth the North gained through the production of enslaved hands. We have not fully understood the status symbol that owning bodies offered. We have not confronted the humanity, the emotions, the heartbeats of the multiple generations who were born into slavery and died in it, who never tasted freedom on America's land. The same goes for the Civil War. We have refused to honestly confront the fact that so many were willing to die in order to hold the freedom of others in their hands. We have refused to acknowledge slavery's role at all, preferring to boil things down to the far more palatable "state's rights." We have not confessed that the end of slavery was so bitterly resented, the rise of Jim Crow became inevitable - and with it, a belief in Black inferiority that lives on in hearts and minds today. We have painted the hundred-year history of Jim Crow as little more than mean signage and the inconvenience that white people and Black people could not drink from the same fountain. But those signs weren't just "mean". They were perpetual reminders of the swift humiliation and brutal violence that could be suffered at any moment in the presence of whiteness. Jim Crow meant paying taxes for services one could not fully enjoy; working for meager wages; and owning nothing that couldn't be snatched away. For many black families, it meant never building wealth and never having legal recourse for injustice. The mob violence, the burned-down homes, the bombed churches and businesses, the Black bodies that were lynched every couple of days - Jim Crow was walking through life measuring every step. Even our celebrations of the Civil Rights Movement are sanitized, its victories accentuated while the battles are whitewashed. We have not come to grips with the spitting and shouting, the pulling and tugging, the clubs, dogs, bombs, and guns, the passion and vitriol with which the rights of Black Americans were fought against. We have not acknowledged the bloodshed that often preceded victory. We would rather focus on the beautiful words of Martin Luther King Jr. than on the terror he and protesters endured at marches, boycotts, and from behind jail doors. We don't want to acknowledge that for decades, whiteness fought against every civil right Black Americans sought - from sitting at lunch counters and in integrated classrooms to the right to vote and have a say in how our country was run. We like to pretend that all those white faces who carried protest signs and batons, who turned on their sprinklers and their fire hoses, who wrote against the demonstrations and preached against the changes, just disappeared. We like to pretend that they were won over, transformed, the moment King proclaimed, "I have a dream." We don't want to acknowledge that just as Black people who experienced Jim Crow are still alive, so are the white people who vehemently protected it - who drew red lines around Black neighborhoods and divested them of support given to average white citizens. We ignore that white people still avoid Black neighborhoods, still don't want their kids going to predominantly Black schools, still don't want to destroy segregation. The moment Black Americans achieved freedom from enslavement, America could have put to death the idea of Black inferiority. But whiteness was not prepared to sober up from the drunkenness of power over another people group. Whiteness was not ready to give up the ability to control, humiliate, or do violence to any Black body in the vicinity - all without consequence.

The explanation may be that gene activity in our muscles changes when the muscles don’t contract for long periods of time. In one experiment, researchers at the University of Massachusetts asked a group of healthy young men to walk around using crutches such that the muscles in their left legs never contracted. After only two days of inactivity, the scientists biopsied muscles in both legs. In the left leg, the DNA repair mechanism had been disrupted, insulin response was dropping, oxidative stress was rising, and metabolic activity within individual muscle cells was slowing.

Having outgrown its Manhattan headquarters, most of Bell Labs moved to two hundred rolling acres in Murray Hill, New Jersey. Mervin Kelly and his colleagues wanted their new home to feel like an academic campus, but without the segregation of various disciplines into different buildings. They knew that creativity came through chance encounters. “All buildings have been connected so as to avoid fixed geographical delineation between departments and to encourage free interchange and close contact among them,” an executive wrote.11 The corridors were extremely long, more than the length of two football fields, and designed to promote random meetings among people with different talents and specialties, a strategy that Steve Jobs replicated in designing Apple’s new headquarters seventy years later. Anyone walking around Bell Labs might be bombarded with random ideas, soaking them up like a solar cell. Claude Shannon, the eccentric information theorist, would sometimes ride a unicycle up and down the long red terrazzo corridors while juggling three balls and nodding at colleagues.III It was a wacky metaphor for the balls-in-the-air ferment in the halls.

In full disclosure, this diet—like all other diets—hasn’t been fully proven. The pilot project didn’t include a control group and wasn’t intended as scientific research. We can’t be sure how these outcomes would apply to the general public. But the ideas presented in this book culminate a century of research questioning the calorie balance model of obesity, and represent a fundamentally different way to understand why we gain weight and what we can do about it.7 For those of you with a scientific bent, I’ve included hundreds of supporting studies from many research teams among the references.

ASPARTAME AND MSG: EXCITOTOXINS Aspartame is, in fact, an excitotoxin, one of a group of substances, usually acidic amino acids, that in high amounts react with specialized receptors in the brain, causing destruction of certain types of neurons. A growing number of neurosurgeons and neurologists are convinced that excitotoxins play a critical role in the development of several neurological disorders, including migraines, seizures, learning disorders in children, and neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis (ALS).1 Glutamate and aspartate are two powerful amino acids that act as neurotransmitters in the brain in very small concentrations, but they are also commonly available in food additives. Glutamate is in MSG, a flavor enhancer, and in hydrolyzed vegetable protein, found in hundreds of processed foods. Aspartate is one of three components of aspartame (NutraSweet, Equal), a sugar substitute. In higher concentrations as food additives, these chemicals constantly stimulate brain cells and can cause them to undergo a process of cell death known as excitotoxicity—the cells are excited to death.

Think of it as plastic memory, this force within you which trends you and your fellows toward tribal forms. This plastic memory seeks to return to its ancient shape, the tribal society. It is all around you—the feudatory, the diocese, the corporation, the platoon, the sports club, the dance troupes, the rebel cell, the planning council, the prayer group . . . each with its master and servants, its host and parasites. And the swarms of alienating devices (including these very words!) tend eventually to be enlisted in the argument for a return to “those better times.” I despair of teaching you other ways. You have square thoughts which resist circles.

After simmering years of censorship and repression, the masses finally throng the streets. The chants echoing off the walls to build to a roar from all directions, stoking the courage of the crowds as they march on the center of the capital. Activists inside each column maintain contact with each other via text messages; communications centers receive reports and broadcast them around the city; affinity groups plot the movements of the police via digital mapping. A rebel army of bloggers uploads video footage for all the world to see as the two hosts close for battle. Suddenly, at the moment of truth, the lines go dead. The insurgents look up from the blank screens of their cell phones to see the sun reflecting off the shields of the advancing riot police, who are still guided by close circuits of fully networked technology. The rebels will have to navigate by dead reckoning against a hyper-informed adversary. All this already happened, years ago, when President Mubarak shut down the communications grid during the Egyptian uprising of 2011. A generation hence, when the same scene recurs, we can imagine the middle-class protesters - the cybourgeoisie - will simply slump forward, blind and deaf and wracked by seizures as the microchips in their cerebra run haywire, and it will be up to the homeless and destitute to guide them to safety.

In a study published in the American Journal of Clinical Nutrition,79 we followed 276 middle-aged adults in Quebec for six years, dividing them into categories based on diet. Overall, the participants gained about 6 pounds (quite typical for this age group), but with huge individual variation—ranging from a 20-pound weight loss to a 30-pound weight gain. For those consuming a high-carbohydrate/low-fat diet, Insulin-30 strongly predicted this variation. That is, people with low insulin secretion gained on average virtually no weight, whereas those with high insulin secretion gained on average more than 10 pounds. In contrast, Insulin-30 had no relationship to weight gain among those consuming a low-carbohydrate/high-fat diet.

In the winter of 1990-1991, she made seven visits to shelters for the homeless. Some met her with aggressive questions comparing her living situation with theirs. She listened attentively. She appeared to be comfortable in all situations. When Barbara Bush, wife of President George Bush, visited in London, Diana took her to Middlesex Hospital to visit AIDS patients. One patient asked Diana why she spent time with suffering people. She answered, “Anywhere I see suffering, that is where I want to be, doing what I can.” She also visited Broadmoor, a maximum-security prison. She talked with some inmates in groups and with some in their cells. “Living with the royal family is an ideal preparation for going to Broadmoor,” she joked.

The differentiation of organ systems, organ parts, etc, is a stepwise affair which has been compared to the way a sculptor carves a statue out of a block of wood. With each step in the development the functions assigned to each group of cells become more precise, and more of its genetic potential is suppressed-until in the end most cells lose even their basic freedom to divide. By the time the fertilized ovum has developed into an adult organism, the individual cell has been reduced from totipotentiality to almost nullipotentiality. It still carries the coded blue-print of the whole organism in its chromosomes, but all, except that tiny fraction of the code which regulates its specialized activities, has been permanently switched off.

By 2011, enough data had been accumulated to show that some risk existed due to long-term, heavy use of mobile phones, compelling the International Agency for Research on Cancer, a branch of the World Health Organization, to classify mobile cell phone radiation in the Group 2B category, indicating a possible carcinogen (a substance or source of exposure that can cause cancer).14 This is the same category as DDT, lead, engine exhaust, chloroform, and glyphosate (the active ingredient in Roundup®). Later, in 2016, a $25 million study conducted by the National Toxicology Program (NTP), part of the National Institutes of Health, confirmed what many have believed for years—that exposure to EMF radiation emitted from cell phones can lead to serious health issues including brain and heart tumors.

We may regard the cell quite apart from its familiar morphological aspects, and contemplate its constitution from the purely chemical standpoint. We are obliged to adopt the view, that the protoplasm is equipped with certain atomic groups, whose function especially consists in fixing to themselves food-stuffs, of importance to the cell-life. Adopting the nomenclature of organic chemistry, these groups may be designated side-chains. We may assume that the protoplasm consists of a special executive centre (Leistungs-centrum) in connection with which are nutritive side-chains... The relationship of the corresponding groups, i.e., those of the food-stuff, and those of the cell, must be specific. They must be adapted to one another, as, e.g., male and female screw (Pasteur), or as lock and key (E. Fischer).

I have shown experimentally that any group of bulbar or spinal nerve cells taken from vertebrates, if deprived of their structural bonds of restraining influences and allowed to undergo a certain degree of degradation, will display permanent automatic, rhythmic, synchronized activity of remarkable regularity. Rhythmic activity, therefore, seems a basic property of pools of nervous elements. ....The rhythm is not something generated through an input rhythm, but is itself a primary rhythm which may be released and even speeded up or retarded by the input, but is not derived from the input. So we have experimental evidence that rhythmic automatism, autonomy of pattern, and hierarchical organization are primary attributes of even the simplest nervous systems, and I think that this unifies our ciew of the nervous system.

The tribal ceremonies of birth, initiation, marriage, burial, installation, and so forth, serve to translate the individual's life-crises and life-deeds into classic, impersonal forms. They disclose him to himself, not as this personality or that, but as the warrior, the bride, the widow, the priest, the chieftain; at the same time rehearsing for the rest of the community the old lesson of the archetypal stages. All participate in the ceremonial according to rank and function. The whole society becomes visible to itself as an imperishable living unit. Generations of individuals pass, like anonymous cells from a living body; but the sustaining, timeless form remains. By an enlargement of vision to embrace this superindividual, each discovers himself enhanced, enriched, supported, and magnified. His role, however unimpressive, is seen to be intrinsic to the beautiful festival-image of man—the image, potential yet necessarily inhibited, within himself. Social duties continue the lesson of the festival into normal, everyday existence, and the individual is validated still. Conversely, indifference, revolt—or exile—break the vitalizing connectives. From the standpoint of the social unit, the broken-off individual is simply nothing—waste. Whereas the man or woman who can honestly say that he or she has lived the role—whether that of priest, harlot, queen, or slave—is something in the full sense of the verb to be. Rites of initiation and installation, then, teach the lesson of the essential oneness of the individual and the group; seasonal festivals open a larger horizon. As the individual is an organ of society, so is the tribe or city—so is humanity entire—only a phase of the mighty organism of the cosmos.

Like, where's he really from?" Eden crumples the napkin in her fist, her skin prickling. "Excuse me?" "Oh, you know what I mean. Is he Korean or Japanese?" A flicker of annoyance makes Eden work her jaw. "What's it matter?" "He just looks so much like that guy from that K-pop group." She snaps her fingers, straining her two brain cells for a name. "Taehung? Or Mingyu? I guess it would be alright if he's Chinese, too, but..." "You need to piss off," Eden snaps, slowly rising from her seat. "Right now." "What's your problem?" "Look, I'm going to give you the benefit of a doubt here and say that you're clearly too sauced to be thinking straight, but what you're saying is... Yeah, just ew." "I just want to know more about him." "Then how about asking for his name first?" "You're making this weird." "You handled that all on your own when you asked where he was really from.

The things once rearing and dwelling in this frightful masonry in the age of dinosaurs were not indeed dinosaurs, but far worse. Mere dinosaurs were new and almost brainless objects—but the builders of the city were wise and old, and had left certain traces in rocks even then laid down well-nigh a thousand million years… rocks laid down before the true life of earth had advanced beyond plastic groups of cells… rocks laid down before the true life of earth had existed at all. They were the makers and enslavers of that life, and above all doubt the originals of the fiendish elder myths which things like the Pnakotic Manuscripts and the Necronomicon affrightedly hint about. They were the Great Old Ones that had filtered down from the stars when earth was young—the beings whose substance an alien evolution had shaped, and whose powers were such as this planet had never bred.

The things once rearing and dwelling in this frightful masonry in the age of dinosaurs were not indeed dinosaurs, but far worse. Mere dinosaurs were new and almost brainless objects - but the builders of the city were wise and old, and had left certain traces in rocks even then laid down well nigh a thousand million years - rocks laid down before the true life of earth had advanced beyond plastic groups of cells - rocks laid down before the true life of earth had existed at all. They were the makers and enslavers of that life, and above all doubt the originals of the fiendish elder myths which things like the Pnakotic Manuscripts and the Necronomicon affrightedly hint about. They were the great "Old Ones" that had filtered down from the stars when earth was young - the beings whose substance an alien evolution had shaped, and whose powers were such as this planet had never bred.

However, there is one fundamental feature of the sexes which can be used to label males as males, and females as females, throughout animals and plants. This is that the sex cells or ‘gametes’ of males are much smaller and more numerous than the gametes of females. This is true whether we are dealing with animals or plants. One group of individuals has large sex cells, and it is convenient to use the word female for them. The other group, which it is convenient to call male, has small sex cells. The difference is especially pronounced in reptiles and in birds, where a single egg cell is big enough and nutritious enough to feed a developing baby for several weeks. Even in humans, where the egg is microscopic, it is still many times larger than the sperm. As we shall see, it is possible to interpret all the other differences between the sexes as stemming from this one basic difference.

Beyond serving as an inspiration to engineers, the group behavior of fireflies has broader significance for science as a whole. It represents one of the few tractable instances of a complex, self-organizing system, where millions of interactions occur simultaneously—when everyone changes the state of everyone else. Virtually all the major unsolved problems in science today have this intricate character. Consider the cascade of biochemical reactions in a single cell and their disruption when the cell turns cancerous; the booms and crashes of the stock market; the emergence of consciousness from the interplay of trillions of neurons in the brain; the origin of life from a meshwork of chemical reactions in the primordial soup. All these involve enormous numbers of players linked in complex webs. In every case, astonishing patterns emerge spontaneously. The richness of the world around us is due, in large part, to the miracle of self-organization.

I don't know what kind of man I would have grown to be had I not served time at The Wilkinson Home for Boys. I don't know how those months and the events that occurred there shaped the person I became, how much they colored my motives or my actions. I don't know if they made me any braver or any weaker. I don't know if the illnesses I've suffered as an adult have been the result of those ruinous months. I'll never know if my distrust of most people and my unease when placed in group situations are byproducts of those days or simply the result of a shy personality. I do know the dreams and nightmares I've had all these years are born of the nights spent in that cell at Wilkinson. That the scars I carry, both mental and physical, are gifts of a system that treated children as prey. The images that screen across my mind in the lonely hours are mine to bear alone, shared only by the silent community of sufferers who once lived as I did, in a world that was deaf to our screams.

Race and racism are power constructs of the modern world. For roughly two hundred thousand years, before race and racism were constructed in the fifteenth century, humans saw color but did not group the colors into continental races, did not commonly attach negative and positive characteristics to those colors and rank the races to justify racial inequity, to reinforce racist power and policy. Racism is not even six hundred years old. It’s a cancer that we’ve caught early. But racism is one of the fastest-spreading and most fatal cancers humanity has ever known. It is hard to find a place where its cancer cells are not dividing and multiplying. There is nothing I see in our world today, in our history, giving me hope that one day antiracists will win the fight, that one day the flag of antiracism will fly over a world of equity. What gives me hope is a simple truism. Once we lose hope, we are guaranteed to lose. But if we ignore the odds and fight to create an antiracist world, then we give humanity a chance to one day survive, a chance to live in communion, a chance to be forever free.

As information processing machines, our ability to process data about the external world begins at the level of sensory perception. Although most of us are rarely aware of it, our sensory receptors are designed to detect information at the energy level. Because everything around us - the air we breathe, even the materials we use to build with, are composed of spinning and vibrating atomic particles, you and I are literally swimming in a turbulent sea of electromagnetic fields. We are part of it. We are enveloped within in, and through our sensory apparatus we experience what is. Each of our sensory systems is made up of a complex cascade of neurons that process the incoming neural code from the level of the receptor to specific areas within the brain. Each group of neurons along the cascade alters or enhances the code, and passes it on to the next set of cells in the system, which further defines and refines the message. By the time the code reaches the outermost portion of our brain, the higher levels of the cerebral cortex, we become conscious of the stimulation. However, if any of the cells along the pathway fail in their ability to function normally, then the final perception is skewed away from normal reality.

Al-Zawahiri, the son of an upper middle-class family who had grown up in Al-Maadi, an affluent Cairene suburb, joined the Muslim Brotherhood at the age of fifteen right after the 1967 defeat. He quickly moved from the Brotherhood's ordinary ranks to join (and create) independent, highly radicalized cells. Though he had no links to the murder of Sadat, he was imprisoned in the major incarceration waves that followed the crime, and was sentenced to three years. Having served his prison sentence, he emigrated to Saudi Arabia, then soon afterwards to Afghanistan to join in the fight against the Soviets. It was during that time that he met Dr Abdullah Azzam, the Palestinian godfather of many militant Islamic groups and the founder of the Jihad Service Bureau, the vehicle that helped recruit thousands of Arabs to the Afghanistan War. Al-Zawahiri became a close friend and confidant of Azzam. After the Soviets' withdrawal from Afghanistan, he returned to Egypt where he became the effective leader of the Al-Jihad group. In 1992, Dr Al-Zawahiri joined his old Arab Afghan colleague, the Saudi multi-millionaire Osama bin Laden, in Sudan, and from there he continued to lead Al-Jihad, until its merger with Al-Qaeda in 1998. Dr Al-Zawahiri presented his thinking and rationale for ‘jihad by all means’ in his book Knights under the Prophet's Banner.38

I described living cells as being crammed full of protein molecules. Acting individually or in small assemblies, they perform reiterated molecular processes that can be regarded, I argued, as a form of computation. Moreover, large numbers of proteins linked into huge interacting networks operate, in effect, like circuits of electrical or electronic devices. Networks of this kind are the basis for the animate wanderings of single cells and their ability to choose what to do next. Here I have broadened the view to encompass multiple cells - 'societies' of cells. Through a variety of strategies - including diffusive hormones, electrical signals, and mechanical interactions - the computational networks of individual cells are linked. During evolution, cells acquired the capacity to work together in social groups; it became advantageous for most cells to become highly specialised. Liver cells, muscle cells, skin cells, and so on abandoned their opportunities for unlimited replication. They began the communal expansion of interlinked abilities that led to the plants and animals we see around us today. But the basis of this diversification of cell chemistry was yet another form of computation - one that operates on DNA. Control mechanisms, again based on protein switches, created extensive but subtle modifications of the core genetic information.

Working independently, Baltimore and Temin discovered an enzyme found in retroviruses that could build DNA from an RNA template. They called the enzyme reverse transcriptase-"reverse" because it inverted the normal direction of information flow: from RNA back to DNA, or from a gene's message backward to a gene, thereby violating Crick's "central dogma" (that genetic information only moved from genes to messages, but never backward). Using reverse transcriptase, ever RNA in a cell could be used as a template to build its corresponding gene. A biologist could thus generate a catalog, or "library" of all "active" genes in a cell-akin to a library of books grouped by subject. There would be a library of genes for T cells and another for red blood cells, a library for neurons in the retina, for insulin-secreting cells of the pancreas, and so forth. By comparing libraries derived from two cells-a T cell and a pancreas cell, say-an immunologist could fish out genes that were active in one cell and not the other (e.g., insulin or the T cell receptor). Once identified, that gene could be amplified a millionfold in bacteria. The gene could be isolated and sequenced, its RNA and protein sequence determined, its regulatory regions identified; it could be mutated an inserted into a different cell to decipher the gene's structure and function. In 1984 this technique was deployed to clone the T cell receptor-a landmark achievement in immunology.

It is conceivable that an interplay of genes and epigenes coordinates human embryogenesis. Let us return, yet again, to Morgan's problem: the creation of a multicellular organism from a one-celled embryo. Seconds after fertilization, a quickening begins in the embryo. Proteins reach into the nucleus of the cell and start flicking genetic switches on and off. A dormant spaceship comes to life. Genes are activated and repressed, and these genes, in turn, encode yet other proteins that activate and repress other genes. A single cell divides to form two, then four, and eight cells. An entire layer of cells forms, then hollows out into the outer skin of a ball. Genes that coordinate metabolism, motility, cell fate, and identity fire "on." The boiler room warms us. The lights flicker on in the corridors. The intercom crackles alive. Now a second code stirs to life to ensure that gene expression is locked into place in each cell, enabling each cell to acquire and fix an identity. Chemical marks are selectively added to certain genes and erased from others, modulating the expression of the genes in that cell alone. Methyl groups are inserted and erased, and histones are modified to repress or activate genes. The embryo unfurls step by step. Primordial segements appear, and cells take their positions along various parts of the embryo. New genes are activated that command subroutines to grow limbs and organs, and more chemical marks are appended on the genomes of individual cells. Cells are added to create organs and structures-forelegs, hind legs, muscles, kidneys, bones, eyes. Some cells die a programmed death. Genes that maintain function, metabolism, and repair are turned on. An organism emerges from a cell.

Mais la question ne se réduit pas seulement à l'ennui que procure cette gent écrivassière ; il faut aussi souligner sa nocivité, car la « stupidité intelligente », surtout dans l'Italie actuelle, est remarquablement organisée. C'est une sorte de franc-maçonnerie implantée dans différents milieux et qui détient pratiquement toutes les positions-clés de l'édition, lorsque celles-ci ne sont pas déjà tenues et contrôlées par des éléments de gauche. Ses représentants possèdent un flair très développé pour reconnaître immédiatement ceux qui ont une nature différente et pour les frapper d'ostracisme. Nous donnerons à ce sujet un exemple banal mais significatif II existe en Italie un groupe d'intellectuels rassemblés autour d'une revue assez largement diffusée et bien faite, qui se voudrait anticonformiste et qui critique volontiers le régime politique et les moeurs d'aujourd'hui. Mais cette revue s'est bien gardée de contacter les rares auteurs qui pourraient lui donner, si elle voulait faire un travail sérieux, une base positive en matière de principes et de vision traditionnelle du monde. Ces auteurs ne sont pas seulement ignorés, ils sont aussi rejetés, exactement comme fait la presse de gauche, précisément parce qu'on sent que ce sont des hommes d'une autre trempe. Cela montre clairement que ce brillant anticonformisme n'est qu'un moyen pour se faire remarquer et pour parader, tout restant sur le plan du dilettantisme. Au demeurant, le fondateur de la revue en question, mort il y a quelques années, n'hésita pas à dire un jour que si un régime différent existait aujourd'hui, il changerait probablement de camp, de façon à être toujours dans l'« opposition» - le but, évidemment, étant de « briller » et d'étaler son « intelligence ».

Sinyukhin began by cutting one branch from each of a series of tomato plants. Then he took electrical measurements around the wound as each plant healed and sent out a new shoot near the cut. He found a negative current—a stream of electrons—flowing from the wound for the first few days. A similar "current of injury" is emitted from all wounds in animals. During the second week, after a callus had formed over the wound and the new branch had begun to form, the current became stronger and reversed its polarity to positive. The important point wasn't the polarity—the position of the measuring electrode with respect to a reference electrode often determines whether a current registers as positive or negative. Rather, Sinyukhin's work was significant because he found a change in the current that seemed related to reparative growth. Sinyukhin found a direct correlation between these orderly electrical events and biochemical changes: As the positive current increased,cells in the area more than doubled their metabolic rate, also becoming more acidic and producing more vitamin C than before. Sinyukhin then applied extra current, using small batteries, to a group of newly lopped plants, augmenting the regeneration current.These battery-assisted plants restored their branches up to three times faster than the control plants. The currents were very small—only 2 to 3 microamperes for five days. (An ampere is a standard unit of electric current, and a microampere is one millionth of an ampere.) Larger amounts of electricity killed the cells and had no growth-enhancing effect. Moreover, the polarity had to match that normally found in the plant. When Sinyukhin used current of the opposite polarity, nullifying the plant's own current, restitution was delayed by two or three weeks.

In silence Peter and I make our way back to my room. We turn left, and a group of people stands at the other end of the hallway. It is the longest of the corridors we will travel through, but that distance shrinks when I see him. Held at either arm by a Dauntless traitor, a gun aimed at the back of his skull. Tobias, blood trailing down the side of his face and marking his white shirt with red; Tobias, fellow Divergent, standing in the mouth of this furnace in which I will burn. Peter’s hands clamp around my shoulders, holding me in place. “Tobias,” I say, and it sounds like a gasp. The Dauntless traitor with the gun presses Tobias toward me. Peter tries to push me forward too, but my feet remain planted. I came here so that no one else would die. I came here to protect as many people as I could. And I care more about Tobias’s safety than anyone else’s. So why am I here, if he’s here? What’s the point? “What did you do?” I mumble. He is just a few feet away from me now, but not close enough to hear me. As he passes me he stretches out his hand. He wraps it around my palm and squeezes. Squeezes, then lets go. His eyes are bloodshot; he is pale. “What did you do?” This time the question tears from my throat like a growl. I throw myself toward him, struggling against Peter’s grip, though his hands chafe. “What did you do?” I scream. “You die, I die too.” Tobias looks over his shoulder at me. “I asked you not to do this. You made your decision. These are the repercussions.” He disappears around the corner. The last I see of him and the Dauntless traitors leading him is the gleam of the gun barrel and blood on the back of his earlobe from an injury I didn’t see before. All the life goes out of me as soon as he’s gone. I stop struggling and let Peter’s hands push me toward my cell.

the device had the property of transresistance and should have a name similar to devices such as the thermistor and varistor, Pierce proposed transistor. Exclaimed Brattain, “That’s it!” The naming process still had to go through a formal poll of all the other engineers, but transistor easily won the election over five other options.35 On June 30, 1948, the press gathered in the auditorium of Bell Labs’ old building on West Street in Manhattan. The event featured Shockley, Bardeen, and Brattain as a group, and it was moderated by the director of research, Ralph Bown, dressed in a somber suit and colorful bow tie. He emphasized that the invention sprang from a combination of collaborative teamwork and individual brilliance: “Scientific research is coming more and more to be recognized as a group or teamwork job. . . . What we have for you today represents a fine example of teamwork, of brilliant individual contributions, and of the value of basic research in an industrial framework.”36 That precisely described the mix that had become the formula for innovation in the digital age. The New York Times buried the story on page 46 as the last item in its “News of Radio” column, after a note about an upcoming broadcast of an organ concert. But Time made it the lead story of its science section, with the headline “Little Brain Cell.” Bell Labs enforced the rule that Shockley be in every publicity photo along with Bardeen and Brattain. The most famous one shows the three of them in Brattain’s lab. Just as it was about to be taken, Shockley sat down in Brattain’s chair, as if it were his desk and microscope, and became the focal point of the photo. Years later Bardeen would describe Brattain’s lingering dismay and his resentment of Shockley: “Boy, Walter hates this picture. . . . That’s Walter’s equipment and our experiment,

the absence of an ‘international standard burglar’, the nearest I know to a working classification is one developed by a U.S. Army expert [118]. Derek is a 19-year old addict. He's looking for a low-risk opportunity to steal something he can sell for his next fix. Charlie is a 40-year old inadequate with seven convictions for burglary. He's spent seventeen of the last twenty-five years in prison. Although not very intelligent he is cunning and experienced; he has picked up a lot of ‘lore’ during his spells inside. He steals from small shops and suburban houses, taking whatever he thinks he can sell to local fences. Bruno is a ‘gentleman criminal’. His business is mostly stealing art. As a cover, he runs a small art gallery. He has a (forged) university degree in art history on the wall, and one conviction for robbery eighteen years ago. After two years in jail, he changed his name and moved to a different part of the country. He has done occasional ‘black bag’ jobs for intelligence agencies who know his past. He'd like to get into computer crime, but the most he's done so far is stripping $100,000 worth of memory chips from a university's PCs back in the mid-1990s when there was a memory famine. Abdurrahman heads a cell of a dozen militants, most with military training. They have infantry weapons and explosives, with PhD-grade technical support provided by a disreputable country. Abdurrahman himself came third out of a class of 280 at the military academy of that country but was not promoted because he's from the wrong ethnic group. He thinks of himself as a good man rather than a bad man. His mission is to steal plutonium. So Derek is unskilled, Charlie is skilled, Bruno is highly skilled and may have the help of an unskilled insider such as a cleaner, while Abdurrahman is not only highly skilled but has substantial resources.

Inmates would overwhelmingly welcome segregation. As Lexy Good, a white prisoner in San Quentin State Prison explained, “I’d rather hang out with white people, and blacks would rather hang out with people of their own race.” He said it was the same outside of prison: “Look at suburbia. . . . People in society self-segregate.” Another white man, using the pen name John Doe, wrote that jail time in Texas had turned him against blacks: '[B]ecause of my prison experiences, I cannot stand being in the presence of blacks. I can’t even listen to my old, favorite Motown music anymore. The barbarous and/or retarded blacks in prison have ruined it for me. The black prison guards who comprise half the staff and who flaunt the dominance of African-American culture in prison and give favored treatment to their “brothers” have ruined it for me.' He went on: '[I]n the aftermath of the Byrd murder [the 1998 dragging death in Jasper, Texas] I read one commentator’s opinion in which he expressed disappointment that ex-cons could come out of prison with unresolved racial problems “despite the racial integration of the prisons.” Despite? Buddy, do I have news for you! How about because of racial integration?' (emphasis in the original) A man who served four years in a California prison wrote an article for the Los Angeles Times called “Why Prisons Can’t Integrate.” “California prisons separate blacks, whites, Latinos and ‘others’ because the truth is that mixing races and ethnic groups in cells would be extremely dangerous for inmates,” he wrote. He added that segregation “is looked on by no one—of any race—as oppressive or as a way of promoting racism.” He offered “Rule No. 1” for survival: “The various races and ethnic groups stick together.” There were no other rules. He added that racial taboos are so complex that only a person of the same race can be an effective guide.

It may seem paradoxical to claim that stress, a physiological mechanism vital to life, is a cause of illness. To resolve this apparent contradiction, we must differentiate between acute stress and chronic stress. Acute stress is the immediate, short-term body response to threat. Chronic stress is activation of the stress mechanisms over long periods of time when a person is exposed to stressors that cannot be escaped either because she does not recognize them or because she has no control over them. Discharges of nervous system, hormonal output and immune changes constitute the flight-or-fight reactions that help us survive immediate danger. These biological responses are adaptive in the emergencies for which nature designed them. But the same stress responses, triggered chronically and without resolution, produce harm and even permanent damage. Chronically high cortisol levels destroy tissue. Chronically elevated adrenalin levels raise the blood pressure and damage the heart. There is extensive documentation of the inhibiting effect of chronic stress on the immune system. In one study, the activity of immune cells called natural killer (NK) cells were compared in two groups: spousal caregivers of people with Alzheimer’s disease, and age- and health-matched controls. NK cells are front-line troops in the fight against infections and against cancer, having the capacity to attack invading micro-organisms and to destroy cells with malignant mutations. The NK cell functioning of the caregivers was significantly suppressed, even in those whose spouses had died as long as three years previously. The caregivers who reported lower levels of social support also showed the greatest depression in immune activity — just as the loneliest medical students had the most impaired immune systems under the stress of examinations. Another study of caregivers assessed the efficacy of immunization against influenza. In this study 80 per cent among the non-stressed control group developed immunity against the virus, but only 20 per cent of the Alzheimer caregivers were able to do so. The stress of unremitting caregiving inhibited the immune system and left people susceptible to influenza. Research has also shown stress-related delays in tissue repair. The wounds of Alzheimer caregivers took an average of nine days longer to heal than those of controls. Higher levels of stress cause higher cortisol output via the HPA axis, and cortisol inhibits the activity of the inflammatory cells involved in wound healing. Dental students had a wound deliberately inflicted on their hard palates while they were facing immunology exams and again during vacation. In all of them the wound healed more quickly in the summer. Under stress, their white blood cells produced less of a substance essential to healing. The oft-observed relationship between stress, impaired immunity and illness has given rise to the concept of “diseases of adaptation,” a phrase of Hans Selye’s. The flight-or-fight response, it is argued, was indispensable in an era when early human beings had to confront a natural world of predators and other dangers. In civilized society, however, the flight-fight reaction is triggered in situations where it is neither necessary nor helpful, since we no longer face the same mortal threats to existence. The body’s physiological stress mechanisms are often triggered inappropriately, leading to disease. There is another way to look at it. The flight-or-fight alarm reaction exists today for the same purpose evolution originally assigned to it: to enable us to survive. What has happened is that we have lost touch with the gut feelings designed to be our warning system. The body mounts a stress response, but the mind is unaware of the threat. We keep ourselves in physiologically stressful situations, with only a dim awareness of distress or no awareness at all.

The climate for relationships within an innovation group is shaped by the climate outside it. Having a negative instead of a positive culture can cost a company real money. During Seagate Technology’s troubled period in the mid-to-late 1990s, the company, a large manufacturer of disk drives for personal computers, had seven different design centers working on innovation, yet it had the lowest R&D productivity in the industry because the centers competed rather than cooperated. Attempts to bring them together merely led people to advocate for their own groups rather than find common ground. Not only did Seagate’s engineers and managers lack positive norms for group interaction, but they had the opposite in place: People who yelled in executive meetings received “Dog’s Head” awards for the worst conduct. Lack of product and process innovation was reflected in loss of market share, disgruntled customers, and declining sales. Seagate, with its dwindling PC sales and fading customer base, was threatening to become a commodity producer in a changing technology environment. Under a new CEO and COO, Steve Luczo and Bill Watkins, who operated as partners, Seagate developed new norms for how people should treat one another, starting with the executive group. Their raised consciousness led to a systemic process for forming and running “core teams” (cross-functional innovation groups), and Seagate employees were trained in common methodologies for team building, both in conventional training programs and through participation in difficult outdoor activities in New Zealand and other remote locations. To lead core teams, Seagate promoted people who were known for strong relationship skills above others with greater technical skills. Unlike the antagonistic committees convened during the years of decline, the core teams created dramatic process and product innovations that brought the company back to market leadership. The new Seagate was able to create innovations embedded in a wide range of new electronic devices, such as iPods and cell phones.

Suppose you entered a boat race. One hundred rowers, each in a separate rowboat, set out on a ten-mile race along a wide and slow-moving river. The first to cross the finish line will win $10,000. Halfway into the race, you’re in the lead. But then, from out of nowhere, you’re passed by a boat with two rowers, each pulling just one oar. No fair! Two rowers joined together into one boat! And then, stranger still, you watch as that rowboat is overtaken by a train of three such rowboats, all tied together to form a single long boat. The rowers are identical septuplets. Six of them row in perfect synchrony while the seventh is the coxswain, steering the boat and calling out the beat for the rowers. But those cheaters are deprived of victory just before they cross the finish line, for they in turn are passed by an enterprising group of twenty-four sisters who rented a motorboat. It turns out that there are no rules in this race about what kinds of vehicles are allowed. That was a metaphorical history of life on Earth. For the first billion years or so of life, the only organisms were prokaryotic cells (such as bacteria). Each was a solo operation, competing with others and reproducing copies of itself. But then, around 2 billion years ago, two bacteria somehow joined together inside a single membrane, which explains why mitochondria have their own DNA, unrelated to the DNA in the nucleus.35 These are the two-person rowboats in my example. Cells that had internal organelles could reap the benefits of cooperation and the division of labor (see Adam Smith). There was no longer any competition between these organelles, for they could reproduce only when the entire cell reproduced, so it was “one for all, all for one.” Life on Earth underwent what biologists call a “major transition.”36 Natural selection went on as it always had, but now there was a radically new kind of creature to be selected. There was a new kind of vehicle by which selfish genes could replicate themselves. Single-celled eukaryotes were wildly successful and spread throughout the oceans.

La société moderne a commis la sérieuse faute de substituer, dès le plus bas âge, l’école à l’enseignement familial. Elle y a été obligée par la trahison des femmes. Celles-ci abandonnent leurs enfants au kindergarten pour s’occuper de leur carrière, de leurs ambitions mondaines, de leurs plaisirs sexuels, de leurs fantaisies littéraires ou artistiques, ou simplement pour jouer au bridge, aller au cinéma, perdre leur temps dans une paresse affairée. Elles ont causé ainsi l’extinction du groupe familial, où l’enfant grandissait en compagnie d’adultes et apprenait beaucoup d’eux. Les jeunes chiens élevés dans des chenils avec des animaux du même âge sont moins développés que ceux qui courent en liberté avec leurs parents. Il en est de même des enfants perdus dans la foule des autres enfants et de ceux qui vivent avec des adultes intelligents. L’enfant modèle facilement ses activités physiologiques, affectives et mentales sur celles de son milieu. Aussi reçoit-il peu des enfants de son âge. Quand il est réduit à n’être qu’une unité dans une école, il se développe mal. Pour progresser, l’individu demande la solitude relative, et l’attention du petit groupe familial. C’est également grâce à son ignorance de l’individu que la société moderne atrophie les adultes. L’homme ne supporte pas impunément le mode d’existence et le travail uniforme et stupide imposé aux ouvriers d’usine, aux employés de bureau, à ceux qui doivent assurer la production en masse. Dans l’immensité des villes modernes, il est isolé et perdu. Il est une abstraction économique, une tête du troupeau. Il perd sa qualité d’individu. Il n’a ni responsabilité, ni dignité. Au milieu de la foule émergent les riches, les politiciens puissants, les bandits de grande envergure. Les autres ne sont qu’une poussière anonyme. Au contraire, l’individu garde sa personnalité quand il fait partie d’un groupe où il est connu, d’un village, d’une petite ville, où son importance relative est plus grande, dont il peut espérer devenir, à son tour, un citoyen influent. La méconnaissance théorique de l’individualité a amené sa disparition réelle.

« Nous sommes toujours en 1929 et, cette année-là, George Washington Hill (1884-1946), président de l’American Tobacco Co., décide de s'attaquer au tabou qui interdit à une femme de fumer en public, un tabou qui, théoriquement, faisait perdre à sa compagnie la moitié de ses profits. Hill embauche Bernays, qui, de son côté, consulte aussitôt le psychanalyste Abraham Arden Brill (1874-1948), une des premières personnes à exercer cette profession aux États-Unis. Brill explique à Bernays que la cigarette est un symbole phallique représentant le pouvoir sexuel du mâle : s’il était possible de lier la cigarette à une forme de contestation de ce pouvoir, assure Brill, alors les femmes, en possession de leurs propres pénis, fumeraient. La ville de New York tient chaque année, à Pâques, une célèbre et très courue parade. Lors de celle de 1929, un groupe de jeunes femmes avaient caché des cigarettes sous leurs vêtements et, à un signal donné, elles les sortirent et les allumèrent devant des journalistes et des photographes qui avaient été prévenus que des suffragettes allaient faire un coup d’éclat. Dans les jours qui suivirent, l’événement était dans tous les journaux et sur toutes les lèvres. Les jeunes femmes expliquèrent que ce qu'elles allumaient ainsi, c'était des « flambeaux de la liberté » (torches of freedom). On devine sans mal qui avait donné le signal de cet allumage collectif de cigarettes et qui avait inventé ce slogan ; comme on devine aussi qu'il s'était agi à chaque fois de la même personne et que c'est encore elle qui avait alerté les médias. Le symbolisme ainsi créé rendait hautement probable que toute personne adhérant à la cause des suffragettes serait également, dans ta controverse qui ne manquerait pas de s'ensuivre sur la question du droit des femmes de fumer en public, du côté de ceux et de celles qui le défendaient - cette position étant justement celle que les cigarettiers souhaitaient voir se répandre. Fumer étant devenu socialement acceptable pour les femmes, les ventes de cigarettes à cette nouvelle clientèle allaient exploser. » Norman Baillargeon, préface du livre d’Edward Bernays, « Propaganda ». (É. Bernays était le neveu de S. Freud)

In this study and others like it, guesswork about a peculiar black predisposition toward unhealthy births imports an old notion about sickle cell disease “afflicting the black race.”25 Whenever I give a talk on this topic, there is inevitably someone in the audience who invokes the mantra that sickle cell anemia is a black genetic disease and therefore proves that race is a genetic category. This misconception was first popularized in the early twentieth century by hematology experts who believed the capacity to develop sickled cells was uniquely inherent in “Negro blood.”26 Stereotypes about black resistance to malaria and susceptibility to sickle cell justified sending black workers to malaria-infested regions in the first part of the century and later led to discriminatory government, employer, and insurance-testing programs in the 1970s.27 The error is easily exposed by looking at two world maps, one highlighting the regions around the globe where malaria is prevalent, the other highlighting areas where sickle cell disease is present. The maps mirror each other perfectly. By comparing them, it is plain to see that malaria and sickle cell aren’t restricted to Africa and that much of Africa is unaffected. High frequencies of the trait also occur in parts of Europe, Oceania, India, and the Middle East, all places where there is malaria. In fact, people in the town of Orchomenos in central Greece have double the rate of sickle cell disease reported among African Americans.28 If frequency of the sickle cell gene determined racial boundaries, it certainly would not prove there is a black race. Instead, as Jared Diamond pointed out in the November 1994 issue of Discover , if we grouped together people by the presence or absence of the sickle cell gene, “we’d place Yemenites, Greeks, New Guineans, Thai, and Dinkas in one ‘race,’ Norwegians and several black African peoples in another.”29 It would be more accurate to call the groups with the sickle cell gene the “antimosquito race.” Of course, that would be a silly way of grouping people, except for studying the sickle cell gene. But “black race” is an equally silly way of grouping people for identifying genetic contributions to disease.

A few hundred million years later, some of these eukaryotes developed a novel adaptation: they stayed together after cell division to form multicellular organisms in which every cell had exactly the same genes. These are the three-boat septuplets in my example. Once again, competition is suppressed (because each cell can only reproduce if the organism reproduces, via its sperm or egg cells). A group of cells becomes an individual, able to divide labor among the cells (which specialize into limbs and organs). A powerful new kind of vehicle appears, and in a short span of time the world is covered with plants, animals, and fungi.37 It’s another major transition. Major transitions are rare. The biologists John Maynard Smith and Eörs Szathmáry count just eight clear examples over the last 4 billion years (the last of which is human societies).38 But these transitions are among the most important events in biological history, and they are examples of multilevel selection at work. It’s the same story over and over again: Whenever a way is found to suppress free riding so that individual units can cooperate, work as a team, and divide labor, selection at the lower level becomes less important, selection at the higher level becomes more powerful, and that higher-level selection favors the most cohesive superorganisms.39 (A superorganism is an organism made out of smaller organisms.) As these superorganisms proliferate, they begin to compete with each other, and to evolve for greater success in that competition. This competition among superorganisms is one form of group selection.40 There is variation among the groups, and the fittest groups pass on their traits to future generations of groups. Major transitions may be rare, but when they happen, the Earth often changes.41 Just look at what happened more than 100 million years ago when some wasps developed the trick of dividing labor between a queen (who lays all the eggs) and several kinds of workers who maintain the nest and bring back food to share. This trick was discovered by the early hymenoptera (members of the order that includes wasps, which gave rise to bees and ants) and it was discovered independently several dozen other times (by the ancestors of termites, naked mole rats, and some species of shrimp, aphids, beetles, and spiders).42 In each case, the free rider problem was surmounted and selfish genes began to craft relatively selfless group members who together constituted a supremely selfish group.

The key point is that these patterns, while mostly stable, are not permanent: certain environmental experiences can add or subtract methyls and acetyls, changing those patterns. In effect this etches a memory of what the organism was doing or experiencing into its cells—a crucial first step for any Lamarck-like inheritance. Unfortunately, bad experiences can be etched into cells as easily as good experiences. Intense emotional pain can sometimes flood the mammal brain with neurochemicals that tack methyl groups where they shouldn’t be. Mice that are (however contradictory this sounds) bullied by other mice when they’re pups often have these funny methyl patterns in their brains. As do baby mice (both foster and biological) raised by neglectful mothers, mothers who refuse to lick and cuddle and nurse. These neglected mice fall apart in stressful situations as adults, and their meltdowns can’t be the result of poor genes, since biological and foster children end up equally histrionic. Instead the aberrant methyl patterns were imprinted early on, and as neurons kept dividing and the brain kept growing, these patterns perpetuated themselves. The events of September 11, 2001, might have scarred the brains of unborn humans in similar ways. Some pregnant women in Manhattan developed post-traumatic stress disorder, which can epigenetically activate and deactivate at least a dozen genes, including brain genes. These women, especially the ones affected during the third trimester, ended up having children who felt more anxiety and acute distress than other children when confronted with strange stimuli. Notice that these DNA changes aren’t genetic, because the A-C-G-T string remains the same throughout. But epigenetic changes are de facto mutations; genes might as well not function. And just like mutations, epigenetic changes live on in cells and their descendants. Indeed, each of us accumulates more and more unique epigenetic changes as we age. This explains why the personalities and even physiognomies of identical twins, despite identical DNA, grow more distinct each year. It also means that that detective-story trope of one twin committing a murder and both getting away with it—because DNA tests can’t tell them apart—might not hold up forever. Their epigenomes could condemn them. Of course, all this evidence proves only that body cells can record environmental cues and pass them on to other body cells, a limited form of inheritance. Normally when sperm and egg unite, embryos erase this epigenetic information—allowing you to become you, unencumbered by what your parents did. But other evidence suggests that some epigenetic changes, through mistakes or subterfuge, sometimes get smuggled along to new generations of pups, cubs, chicks, or children—close enough to bona fide Lamarckism to make Cuvier and Darwin grind their molars.

A church that truly understands the implications of the biblical gospel, letting the “word of Christ dwell in [it] richly” (Col 3:16), will look like an unusual hybrid of various church forms and stereotypes. Because of the inside-out, substitutionary atonement aspect, the church will place great emphasis on personal conversion, experiential grace renewal, evangelism, outreach, and church planting. This makes it look like an evangelical-charismatic church. Because of the upside-down, kingdom/incarnation aspect, the church will place great emphasis on deep community, cell groups or house churches, radical giving and sharing of resources, spiritual disciplines, racial reconciliation, and living with the poor. This makes it look like an Anabaptist “peace” church. Because of the forward-back, kingdom/restoration aspect, the church will place great emphasis on seeking the welfare of the city, neighborhood and civic involvement, cultural engagement, and training people to work in “secular” vocations out of a Christian worldview. This makes it look like a mainline church or, perhaps, a Kuyperian Reformed church. Very few churches, denominations, or movements integrate all of these ministries and emphases. Yet I believe that a comprehensive view of the biblical gospel — one that grasps the gospel’s inside-out, upside-down, and forward-back aspects — will champion and cultivate them all. This is what we mean by a Center Church.

A family's structure is paramilitary, and commanding it is the Capofamiglia, commonly referred to as simply the 'Boss', absolute ruler with unquestioned life or death authority over everyone in the organization. At his side is his Consigliere, an advisor chosen for his loyalty, knowledge of the family business, and political strength internal to the family's alliances and factions. The Boss's second-in-command, the Sotto Capo or 'Underboss', has power that varies depending on the man holding the position. The Underboss more closely runs the day to day activities of the organization and acts as a buffer between the Boss, who gives the orders, and the people responsible for carrying them out. The Underboss is the successor to the Boss in the event of his death, or his representative on the street if the Boss is imprisoned and chooses to run the organization from his cell. The Underboss directly controls a group of Capo Régimes, usually referred to as Capos or Captains; these are the family's middle level managers who run groups of Soldiers, or 'crews'. Since only the Boss, Underboss and Consigliere are above the rank of Capo, it's a powerful position; a Soldier at odds with his Capo is a Soldier with a severely limited life expectancy. Finally, the people who rely on a Soldier's protection and power to conduct their business, yet are not members of the organization, are known as 'connected' guys. To a connected guy, a made guy is his Boss, his agent and his police, all rolled into one; of course in some cases he may also turn out to be his judge, jury and executioner.

The group's growth was dramatic; in under fifteen years, the Brotherhood grew from a single room in Ismailiya to 3,000 branches across the whole of Egypt, and from a tiny cell round Sheikh Al-Banna to more than 450,000 active members.

The FDA will accept a certain level of risk for a new treatment that is to be applied to a group of very sick patients who would otherwise die in the near future, but not for a group who have a relatively long life expectancy on the basis of existing therapies.

Le droit de me lire ne donne pas au lecteur le droit de m'agresser s'il n'aime pas mes idées. Ce genre d'attitudes appartiennent à un autre âge, à une autre époque, celle de l'inquisition, celle du règne de la volonté du groupe, le règne de la négation de l'individu.

Terminology and classification Leukaemias are traditionally classified into four main groups: • acute lymphoblastic leukaemia (ALL) • acute myeloid leukaemia (AML) • chronic lymphocytic leukaemia (CLL) • chronic myeloid leukaemia (CML). In acute leukaemia there is proliferation of primitive stem cells leading to an accumulation of blasts, predominantly in the bone marrow, which causes bone marrow failure. In chronic leukaemia the malignant clone is able to differentiate, resulting in an accumulation of more mature cells. Lymphocytic and lymphoblastic cells are those derived from the lymphoid stem cell (B cells and T cells). Myeloid refers to the other lineages, i.e. precursors of red cells, granulocytes, monocytes and platelets (see Fig. 24.2, p. 989). The diagnosis of leukaemia is usually suspected from an abnormal blood count, often a raised white count, and is confirmed by examination of the bone marrow. This includes the morphology of the abnormal cells, analysis of cell surface markers (immunophenotyping), clone-specific chromosome abnormalities and molecular changes. These results are incorporated in the World Health Organization (WHO) classification of tumours of haematopoietic and lymphoid tissues; the subclassification of acute leukaemias is shown in Box 24.47. The features in the bone marrow not only provide an accurate diagnosis but also give valuable prognostic information, allowing therapy to be tailored to the patient’s disease.

Au-delà de 2017, l’avenir semble moins assuré. C’est pour cette raison qu’en 2010 Christophe de Margerie avait lancé une stratégie offensive d’exploration. Celle-ci s’est révélée assez décevante, sans grande découverte à la clé pour le moment. C’est dans ce contexte que le groupe a annoncé en septembre le recrutement en externe d’un nouveau directeur de l’exploration, l’Américain Kevin McLachlan.

The Party’s organizational tentacles stretched far into community life. The 42 regions (‘Gaue’), 808 districts, 28,376 local groups, 89,378 ‘cells’ and 397,040 ‘blocks’ into which Germany was divided by the Party’s administration ensured that not only members were subjected to invasive controls and routine surveillance.

One result of this productive system is that the middle class has grown from being about 15 percent of the population in 1920 to being 86 percent of the population in 2011. While some of the population always seem to live at the poverty line, the vast majority of Americans today are affluent compared to their grandparents. They have the money to buy the products produced by American industry. In the process, the definition of poverty has changed. The majority of Americans who are classified by the government as living at the poverty level have indoor plumbing, color television sets, cell phones, air-conditioning, washers and dryers, microwaves, automobiles, and access to free health care. They are also a significant buying group.

This is getting weird,” Lip said, flipping through some of the others.  “Do you think these are code?” “Could be.  Don’t know.  Not our speed, though.  We’re going to need to call in some favors to get them run.” Lip nodded.  “That shouldn’t be a problem.  We’ll use our go-to boy.” “Lawrence?” “He owes us.” Lawrence Simpson.  He still worked at the NSA.  Man was a lifer.  And he owed them big. “They’ve got the Black Widow now,” Lip said.  “I’d love to work with that baby.” The Black Widow.  The NSA’s colossal Cray supercomputer.  Thing could scan through millions of emails, phone calls, you name it, in seconds.  It could find patterns, search for key words, and do it on a scale that was unfathomable. “Keep dreaming,” Marks said. Lip could get carried away.  Like the NSA was going to let ‘em use that.  Thing was needed for its job.  Like spying on the world. First time on the job Marks was pretty blown away.  Didn’t faze him in the least now, knowing that the NSA captured every bit of correspondence every day and every second from around the world.  Phone calls, cell or land lines.  Domestic and international.  Emails.  Text messages.  Fuckin’ everything. It was all captured, scanned and stored.  And Lip and he had a hand in helping with that.  Still were helping.  Information in motion.  There were always new pipes that needed to be tapped, more splitters to put in place somewhere around the world.  Dubai, Chóngqing, Bangalore…  Marks and Lip, just two of your friendly cable box installers.  No job too small or too far away. Marks eyed the walls again.  In a micro sense this was almost like a snapshot of the soup.  Random and nonsensical.  Just a bunch of non-related groups lumped together. He examined some of the newspaper clippings.  It was weird to see the paper content. 

In the Tel Aviv study, a group of formerly sedentary rats of varying ages ran on a treadmill for 20 minutes daily for 13 weeks. Another pack of rats was the control group. The control group was allowed to remain sedentary—that is, those rats’ muscles were mainly not used. As you might expect from everything you’ve read so far, the exercisers increased their number of stem muscle cells, with the total increase dependent on age—but not in the way you would expect. The younger rat runners saw an increase of 20 to 35 percent in their stem repair cells. The older rats, however, experienced an even greater proliferation—a 33 to 47 percent increase. That’s right: The percentage increase in stem muscle cells was greater in the older subjects than in the younger ones. On the other hand, the nonexercising rats lost stem cells by lying around, eating and sleeping as they aged.

Still, maybe a good challenge was just what she needed to bring her back to herself. So perhaps the best thing to do was simply to call her and tell her—let loose the dogs of war and let the chips fall where they may. It was a wonderfully mangled metaphor, which made it seem even more convincing, so I stepped away from the group of cops and reached for my cell phone. Deborah

What holds cells in this teetering position? In 2006, a group headed by Eric Lander at the Broad Institute in Boston, found at least part of the answer. A key set of genes in ES cells, the pluripotent cells we have come to know so well, were found to have a really strange histone modification pattern. These were genes that were very important for controlling if an ES cell stayed pluripotent, or differentiated. Histone H3K4 was methylated at these genes, which normally is associated with switching on gene expression. H3K27 was also methylated. This is normally associated with switching off gene expression. So, which modification would turn out to be stronger? Would the genes be switched on or off? The answer turned out to be both. Or neither, depending on which way we look at it. These genes were in a state called ‘poised’. Given the slightest encouragement – a change in culture conditions that pushed cells towards differentiation for example – one or other of these methylations was lost. The gene was fully switched on, or strongly repressed, depending on the epigenetic modification

These findings completely defy the calorie-balance theory of obesity. According to standard advice, the best way to lose weight or avoid weight gain is to cut back on calories. And that’s exactly what we did with the fast-acting carbohydrate group—in essence, we put them on a low-calorie diet. But despite having consumed less food, they had more fat. They also had significantly increased heart disease risk factors. Consistent with the Fat Cell Theory of Obesity figure (see here), the fast-acting carbohydrate increased insulin levels, causing calories to be stored as fat at the expense of the animals’ lean tissues and overall health.

Diabetes is actually a group of diseases, all of which are characterized by the inability to produce enough insulin. Type 1 diabetes, which mostly develops in children, occurs when the immune system destroys cells in the pancreas that make insulin. Gestational diabetes arises occasionally during pregnancy when a mother’s pancreas produces too little insulin, giving both her and the fetus a dangerous, prolonged sugar rush. My grandmother had the third and most common form of the disease, type 2 diabetes (also called adult onset diabetes or diabetes mellitus type 2), which is the focus of this discussion because it is a formerly rare mismatch disease associated with metabolic syndrome that is now one of the fastest growing diseases in the world. Between

Un certain groupe de métiers — se caractérisant par l’usage qu’ils font du feu pour transformer ou ennoblir des matières comme le métal ou les minéraux dont on fait du verre et des émaux — sert de base à une tradition spirituelle qui se rattache à Hermès Trismégiste dont le nom égyptien est Thot et que beaucoup de musulmans comptent au nombre des anciens prophètes. L’art hermétiste par excellence, c’est l’alchimie ; le plus souvent mal comprise, parce que la transmutation qui est son but et qu’elle traduit en termes artisanaux, se situe en réalité au niveau de l’âme. Que l’alchimie ait été pratiquée par beaucoup d’artisans du feu, ne fait aucun doute ; son emblème, le couple de dragons entrelacés — forme médiévale du caducée — orne de nombreux récipients en céramique ou en métal. Nombre d’artisans ou d’artistes, qu’ils aient reçu ou non une initiation correspondant à leur entrée dans une corporation professionnelle, adhéraient ou adhèrent encore à un Ordre soufi (...) on peut également dire que le soufisme se situe là où l’amour et la connaissance convergent. Or, l’objet ultime et commun de l’amour comme de la connaissance n’est autre que la Beauté divine. On comprendra dès lors comment l’art, dans une civilisation théocentrique comme celle de l’Islam, se rattache à l’ésotérisme, dimension la plus intérieure de la tradition. Art et contemplation : l’art a pour objet la beauté formelle, alors que l’objet de la contemplation est la beauté au-delà de la forme qui révèle qualitativement l’ordre formel, tout en le dépassant infiniment. Dans la mesure où l’art s’apparente à la contemplation, il est connaissance, la beauté étant un aspect de la Réalité, au sens absolu du terme. Cela nous ramène au phénomène de scission entre art et artisanat, d’une part, et art et science, d’autre part, phénomène qui a profondément marqué la civilisation européenne moderne : si l’art n’est plus considéré comme une science, c’est-à-dire comme une connaissance, c’est que la beauté, objet de contemplation à divers degrés, n’est plus reconnue comme un aspect du réel. En fait, l’ordre normal des choses a été renversé à un point tel qu’on identifie volontiers la laideur à la réalité, la beauté n’étant plus que l'objet d’un esthétisme aux contours parfaitement subjectifs et changeants. Les conséquences de cette dichotomie de l’expérience du réel sont des plus graves : car c’est finalement la beauté — subtilement rattachée à l’origine même des choses — qui jugera de la valeur ou de la futilité d’un monde. Ainsi que le Prophète l’a dit : « Dieu est beau et II aime la beauté. » p. 296-298

After all, I had spent quite a lot of time in denominations, para-church movements, and “home-cell” groups whose publicly announced intention was “to restore the pure Christianity of the early Church”. Not one of them had ever sent me back to any first- or second-century documentation for evidence. So who knew? Who could have imagined—with so many competing versions of “pure New Testament Christianity” on the market out there—that finding out what the early Church was like might be as simple as opening up the records and having a look? Like

De plus, le fait de structurer, de charpenter ses cours et d'inscrire son action pédagogique dans un cadre strict et précis, en même temps qu'original et attractif, peut contribuer à rassurer les élèves, à structurer leur pensée, à canaliser leurs énergies, tout en ayant un effet bénéfique pour l'enseignant lui aussi, lequel doit mettre en place des scénarios et des stratégies appropriés pour vaincre son angoisse (proche parent et alimentée par celle des élèves) et trouver le calme intérieur en classe, même au milieu des petites tempêtes qui, parfois, agitent ce microcosme parcouru d'incidents divers. Faire fonctionner le cours harmonieusement est une victoire remportée non sur les élèves, mais sur l'adversité, sur les forces de dissolution, d'éclatement et de dispersion, les forces qui agitent le groupe-classe. Dans le contexte actuel, il s'agit là d'un véritable défi pour les enseignants. Dans cet esprit-là, dans cette logique relationnelle là, il n'y a ni échec, ni succès, ni amis, ni ennemis, mais seulement des personnes et des situations existentielles […] dans lesquelles le comportement d'autrui (chef d'établissement, mais aussi élèves, inspecteur, voir collègues) à notre égard permet de mettre à jour nos propres faiblesses et de nous engager dans la voie de leur dépassement progressif. Pour le dire avec les mots de Jung, "tout ce qui m'irrite chez les autres peut servir ma connaissance de moi-même". (p. 88-89)

Logiquement, la démocratie s'oppose à la tyrannie, mais en fait, elle y mène ; c'est-à-dire : comme sa réaction est sentimentale — sans quoi elle serait centripète et tendrait vers la théocratie, seule garantie d'une liberté réaliste — elle n'est qu'un extrême qui, par sa négation irréaliste de l'autorité et de la compétence, appelle fatalement un autre extrême et une nouvelle réaction autoritaire, autoritaire celle-ci et tyrannique par son principe même. L'illusion démocratique apparaît surtout dans les traits suivants : en démocratie, est vrai ce que croit la majorité ; c'est elle qui « crée » pratiquement la vérité ; la démocratie elle-même n'est vraie que dans la mesure où — et aussi longtemps que — la majorité y croit, elle porte donc en son sein les germes de son suicide. L'autorité, qu'on est bien obligé de tolérer sous peine d'anarchie, vit à la merci des électeurs, d'où l'impossibilité de gouverner réellement ; l'idéal de « liberté » fait du gouvernement un prisonnier qui doit suivre constamment les pressions des divers groupes d'intérêt ; les campagnes électorales elles-mêmes prouvent que les aspirants à l'autorité doivent duper les électeurs, et les moyens de cette duperie sont si grossiers et stupides, et constituent un tel avilissement du peuple, que cela devrait suffire pour réduire à néant le mythe de la démocratie moderne. Ce n'est pas à dire qu'aucun genre de démocratie ne soit possible : mais alors il s'agit d'abord de collectivités restreintes — nomades surtout — et ensuite d'une démocratie intérieurement aristocratique et théocratique, non d'un égalitarisme laïc imposé à de grands peuples sédentaires. "La Transfiguration de l'homme" (1995)