Blocker Quotes

I’m a modern man, a man for the millennium. Digital and smoke free. A diversified multi-cultural, post-modern deconstruction that is anatomically and ecologically incorrect. I’ve been up linked and downloaded, I’ve been inputted and outsourced, I know the upside of downsizing, I know the downside of upgrading. I’m a high-tech low-life. A cutting edge, state-of-the-art bi-coastal multi-tasker and I can give you a gigabyte in a nanosecond! I’m new wave, but I’m old school and my inner child is outward bound. I’m a hot-wired, heat seeking, warm-hearted cool customer, voice activated and bio-degradable. I interface with my database, my database is in cyberspace, so I’m interactive, I’m hyperactive and from time to time I’m radioactive. Behind the eight ball, ahead of the curve, ridin the wave, dodgin the bullet and pushin the envelope. I’m on-point, on-task, on-message and off drugs. I’ve got no need for coke and speed. I've got no urge to binge and purge. I’m in-the-moment, on-the-edge, over-the-top and under-the-radar. A high-concept, low-profile, medium-range ballistic missionary. A street-wise smart bomb. A top-gun bottom feeder. I wear power ties, I tell power lies, I take power naps and run victory laps. I’m a totally ongoing big-foot, slam-dunk, rainmaker with a pro-active outreach. A raging workaholic. A working rageaholic. Out of rehab and in denial! I’ve got a personal trainer, a personal shopper, a personal assistant and a personal agenda. You can’t shut me up. You can’t dumb me down because I’m tireless and I’m wireless, I’m an alpha male on beta-blockers. I’m a non-believer and an over-achiever, laid-back but fashion-forward. Up-front, down-home, low-rent, high-maintenance. Super-sized, long-lasting, high-definition, fast-acting, oven-ready and built-to-last! I’m a hands-on, foot-loose, knee-jerk head case pretty maturely post-traumatic and I’ve got a love-child that sends me hate mail. But, I’m feeling, I’m caring, I’m healing, I’m sharing-- a supportive, bonding, nurturing primary care-giver. My output is down, but my income is up. I took a short position on the long bond and my revenue stream has its own cash-flow. I read junk mail, I eat junk food, I buy junk bonds and I watch trash sports! I’m gender specific, capital intensive, user-friendly and lactose intolerant. I like rough sex. I like tough love. I use the “F” word in my emails and the software on my hard-drive is hardcore--no soft porn. I bought a microwave at a mini-mall; I bought a mini-van at a mega-store. I eat fast-food in the slow lane. I’m toll-free, bite-sized, ready-to-wear and I come in all sizes. A fully-equipped, factory-authorized, hospital-tested, clinically-proven, scientifically- formulated medical miracle. I’ve been pre-wash, pre-cooked, pre-heated, pre-screened, pre-approved, pre-packaged, post-dated, freeze-dried, double-wrapped, vacuum-packed and, I have an unlimited broadband capacity. I’m a rude dude, but I’m the real deal. Lean and mean! Cocked, locked and ready-to-rock. Rough, tough and hard to bluff. I take it slow, I go with the flow, I ride with the tide. I’ve got glide in my stride. Drivin and movin, sailin and spinin, jiving and groovin, wailin and winnin. I don’t snooze, so I don’t lose. I keep the pedal to the metal and the rubber on the road. I party hearty and lunch time is crunch time. I’m hangin in, there ain’t no doubt and I’m hangin tough, over and out!

Research shows that playing cards once a week or meeting friends every Wednesday night at Starbucks adds as many years to our lives as taking beta blockers or quitting a pack-a-day smoking habit.

Why do you always have to put you and McNab and sex in my head? It brings pain no blocker can cure.

I'm your personal jock-blocker, baby." Tori reached into her jeans pocket and handed over a half-eaten Snickers bar. "Happy Douche Liberation Day.

Don’t make me turn on the room’s ability blockers. I’m not teaching middle school here. And turn off your phones, people.

Having autism is like having too many tabs open on a computer. Or more accurately, it’s like trying to surf the web without an ad blocker. Every time you click on something, another window pops up.

Comparing is a Gratitude Blocker.

The BIG push means being able to develop and sustain momentum toward your goal; it is the process of actively replacing excuses with winning habits, the ultimate excuses blockers. Moreover, it is being willing to go to the wall for what you want or believe in, to push beyond your previous mental and physical limits, no matter what it takes.

And still, on occasion, I'll disable my social media blockers, and I'll sit there like a rat pressing the lever, like a woman repeatedly hitting myself on the forehead with a hammer, masturbating through the nightmare until I finally catch the gasoline whiff of a good meme.

To put it coldly, my friends, all the ones who should have died years ago, would have died years ago without beta-blockers, stents, angioplasties, pacemakers, exotic medications, well, now they’re dying all at once.” John

The biggest blocker to happiness is "the fear of vulnerability". Happiness cannot enter a caged heart.

I wish I had my beta-blockers handy. [Comment when told that he had won a Nobel prize, referring to the drug he discovered for the treatment of heart disease.]

As he dug into a piece of blue cake, he thought more about his transition: coming out, his first therapy appointment, going on hormone blockers for the first time. He had treated each step as another obstacle to overcome. This was the first time he thought about it as something to celebrate.

He’d complained to his doctor. “The beta-blockers are blocking my memories!” Juan Diego cried. “They are stealing my childhood—they are robbing my dreams!” To his doctor, all this hysteria meant was that Juan Diego missed the kick his adrenaline gave him. (Beta-blockers really do a number on your adrenaline.)

I am uneasy about the suppressive nature of conventional medicine. If you look at the names of the most popular categories of drugs in use today, you will find that most of them begin with the prefix “anti.” We use antispasmodics and antihypertensives, antianxiety agents and antidepressants, antihistamines, antiarrhythmics, antitussives, antipyretics, and anti-inflammatories, as well as beta blockers and H2-receptor antagonists. This is truly antimedicine—medicine that is, in essence, counteractive and suppressive. What

Chemopreventive agents can be classified into different subgroups based on which stage of cancer development they help to fight: Carcinogen blockers and antioxidants help prevent the initial triggering DNA mutation, and antiproliferatives work by keeping tumors from growing and spreading. Curcumin is special in that it appears to belong to all three groups, meaning it may potentially help prevent and/or arrest cancer cell growth.13

For example, if you normally procrastinate by checking social media, use a website blocker (e.g. SelfControl, Freedom, HeyFocus, etc.) to block Facebook and Twitter for 30 minutes at a time. Gradually increase the duration of the blocks each week.

Last year, Mr. Blocker said we could find ourselves in our own writing. All I could think was this: Sounds like a good place to get lost. Yeah, I think I might get lost a hundred times, a thousand times, before I find out who I am and where I'm going.

If you aren’t paranoid before you arrive in this city, give it a few weeks and you will soon notice it creeping in, dripping into your subconscious like a leaky tap. The trick is not to give a flying fuck what anyone thinks about you, and if you are in the right frame of mind this can be an easy trick to perform but if not you’ll soon notice that for a city full of people who do a great Stevie Wonder impersonation when it comes to the homeless and beggars and casual violence towards others, wearing the wrong kind of shoes or a cheap suit brings out a sneering, hateful attitude that can have weaker minded individuals locked in their houses for weeks before harassing their doctors for prescriptions of Prozac and Beta blockers just to make it out the front door.

But now as Phoebus anointed Phaethon With medicinal blocker To protect him from the burning And fixed the crown of rays on the boy’s head He saw the tragedy to come And sighed: “At least, if you can, Stick to these instructions, my son. First: use the whip not at all, or lightly. But rein the team hard. It is not easy. Their whole inclination is to be gone. Second: avoid careering Over the whole five zones of heaven. Keep to that broad highway that curves Within three zones, temperate and tropic. Avoid the poles, and their killing blizzards. Keep to that highway, follow the wheel ruts. Share your heat fairly Between heaven and earth, not too low And not crashing in among the stars. Too high, You will set heaven aflame—and, too low, earth. The middle way is best, and safest. And do not veer too far to the right Where your wheels might crush the Serpent, nor to the left Where they might be shattered against the Altar. Take a bearing between them.

THE FOUR PRACTICES OF THE TALENT MAGNET Among the Multipliers we studied in our research, we found four active practices that together catalyze and sustain this cycle of attraction. These Talent Magnets: 1) look for talent everywhere; 2) find people’s native genius; 3) utilize people at their fullest; and 4) remove the blockers. Let

Many trans adults say that, in retrospect, puberty blockers were helpful, life-saving even. Both Hannah and Phoebe, each of whom has her own chapter in this book, have made this point when speaking to me. But these drugs have not been helpful for everyone – both for those who continue to identify as trans, like Jacob, and for those who do not.

Our bread is not what it used to be. It is more of a Frankenfood, a by-product of industrial agriculture or “super-starch and super-gluten.” Combine that with the damage our guts have suffered from our diet, environment, lifestyle, and overuse of antibiotics, acid blockers, and anti-inflammatories, and you have the perfect storm for gluten intolerance.

In 2022, more than three years after stopping puberty blockers, Jacob is 19 and still trans. He uses a male name and male pronouns, and dresses in a way that he says is typically male. His passport and driving license say male. But he’s not on any medication. He hasn’t chosen to take testosterone and has no plans to. ‘I’m quite content with just being me at the moment.

trans—whatever that means—hasn’t been some crazy plot of mine to deceive people; it’s just been the fact of living every day. Because I was lucky enough to get on puberty blockers, and do my transition young, people think I’m cis, they think I’m just like they are. Is it really my responsibility to out myself over and over, for the rest of my life? What is it, in the end, that makes me different from cis people at this point in my life—besides history?

The pioneers of the Dutch protocol were well aware that the pathway they had devised – puberty blockers, followed by cross-sex hormones and surgery – would not work for all. They acknowledged that by lowering the age at which puberty was blocked, it might ‘increase the incidence of “false positives”.’ It is this group, the group for whom this pathway will not be of benefit, say Hutchinson and others, that has been ignored by gender clinics across the Western world, including GIDS.

How does stress influence the midbrain pleasure circuit (or the feeding control circuits)? The short answer is that we don't really know. However, there are some tantalizing initial clues. Recall that twenty-four hours after a single exposure to cocaine, the excitatory glutamate-using synapses recived by VTA dopamine neurons express LTP. This change, which will result in greater dopamine release in VTA target areas, could also be produced by nicotine, mophine, amphetamines, or alcohol. Amazingly, even breif exposure to stress (a rat's five-minute-long forced swim in cold water) also produced LTP of the VTA synapses that was indistinguishable from that evoked by drugs. What's more, the stress-induced LTP could be prevented by pretreatment with a corticosterone receptor blocker. This suggests that drugs and stress rewire the pleasure circuit in overlapping ways and that the stress response to trigger LTP in the VTA requires a stress hormone signaling loop from the brain to the body and back.

I think the whole area has become politicized,” said psychotherapist Marcus Evans, who resigned from England’s national gender clinic, the Tavistock Foundation, over the lack of careful protocols in its treatment of transgender-identified children. “The drugs, you know, the hormone blockers, first of all, they say it’s a neutral act. What are they talking about? You’re going to powerfully interfere with a person’s biological development,” he said to me over Skype. “I’m not saying you shouldn’t do it…. But you don’t say it’s a neutral act…. They’re not with their peers anymore.

The researchers tried a clever tactic to overcome this problem. They created a number of recipes for common foods including muffins and pasta in which they could disguise placebo ingredients like bran and molasses to match the texture and color of the flax-laden foods. This way, they could randomize people into two groups and secretly introduce tablespoons of daily ground flaxseeds into the diets of half the participants to see if it made any difference. After six months, those who ate the placebo foods started out hypertensive and stayed hypertensive, despite the fact that many of them were on a variety of blood pressure pills. On average, they started the study at 155/81 and ended it at 158/81. What about the hypertensives who were unknowingly eating flaxseeds every day? Their blood pressure dropped from 158/82 down to 143/75. A seven-point drop in diastolic blood pressure may not sound like a lot, but that would be expected to result in 46 percent fewer strokes and 29 percent less heart disease over time.125 How does that result compare with taking drugs? The flaxseeds managed to drop subjects’ systolic and diastolic blood pressure by up to fifteen and seven points, respectively. Compare that result to the effect of powerful antihypertensive drugs, such as calcium-channel blockers (for example, Norvasc, Cardizem, Procardia), which have been found to reduce blood pressure by only eight and three points, respectively, or to ACE inhibitors (such as Vasotec, Lotensin, Zestril, Altace), which drop patients’ blood pressure by only five and two points, respectively.126 Ground flaxseeds may work two to three times better than these medicines, and they have only good side effects. In addition to their anticancer properties, flaxseeds have been demonstrated in clinical studies to help control cholesterol, triglyceride, and blood sugar levels; reduce inflammation, and successfully treat constipation.127 Hibiscus Tea for Hypertension Hibiscus tea, derived from the flower of the same name, is also known as roselle, sorrel, jamaica, or sour tea. With

AND A FEW THAT WEREN’T THE BEST IDEA. NO ONE THOUGHT THE ABILITY RESTRICTOR WOULD WORK—BUT IT DID. EXCEPT THE COUNCIL RUINED IT BY ORDERING SOPHIE TO WEAR IT AND… YEAH. I WISH I’D NEVER MADE IT. I DESTROYED IT, THOUGH—AND I’LL NEVER MAKE ANOTHER! I MADE THESE BLOCKER BANDS TO HELP SOPHIE WITH HER ENHANCING—AND THEY DEFINITELY DID THEIR JOB. BUT USING CRUSH CUFFS KINDA GOT ME STUCK IN THE MOST AWKWARD CONVERSATION EVER.… THE WARDEN ALSO WORKED PERFECTLY AND MONITORED ALVAR’S EVERY MOVE. BUT I WISH I’D MADE SURE IT WAS RESISTANT TO NULLS… FOR THE RECORD, THESE SENSE BLASTERS WERE ACTUALLY WORKING REALLY WELL UNTIL COUNCILLOR ZARINA FRIED ONE WITH LIGHTNING. STILL, I SHOULD’VE PUT AN OVERRIDE BECAUSE FITZ ALMOST GOT KILLED.

The problem that I frequently see crop up is that people have a tendency to treat the Daily Stand-up as simply individual reporting. “I did this … I’ll do that”—then on to the next person. The more optimum approach is closer to a football huddle. A wide receiver might say, “I’m having a problem with that defensive lineman,” to which an offensive blocker might respond, “I’ll take care of that. I’ll open that line.” Or the quarterback might say, “Our running game is hitting a wall; let’s surprise them with a pass to the left.” The idea is for the team to quickly confer on how to move toward victory—i.e., complete the Sprint. Passivity is not only lazy, it actively hurts the rest of the team’s performance. Once spotted, it needs to be eliminated immediately.

It is clear, then, that the desire for certainty shapes our spaces of possibility, our perceptions, and our lives both personally and professionally. Usually, this need saves us. But it also sabotages us. This produces an ongoing tension between what we might think of as our conscious selves and our automatic selves. To overcome our inborn reflex that pushes us to seek certainty (sometimes at any cost), we must lead with our conscious selves and tell ourselves a new story, one that with insistent practice will change our future past and even our physiological responses. We must create internal and external ecologies that… celebrate doubt! This means the biggest obstacle to deviation and seeing differently isn’t actually our environment as such, or our” intelligence, or even—ironically—the challenge of reaching the mythical “aha” moment. Rather, it is the nature of human perception itself, and in particular the perceived need for knowing. Yet the deep paradox is that the mechanisms of perception are also the process by which we can unlock powerful new perceptions and ways to deviate. Which means that mechanism of generating a perception is the blocker… and the process of creating perception is the enabler of creativity

He experienced a range of intense and unpleasant side effects [on puberty blockers], as he tried different doses. ‘On one of them I had really bad insomnia. And another one, I had really bad anger problems.’ … ‘Your mood goes like it’s a roller coaster,’ he explains. ‘There are moments when you’re euphorically happy. The next day, you crash really bad and you are exhausted. And then you’re really, really depressed, like, suicidal depressed.’ Jacob says he had felt depressed before starting on puberty blockers and had experienced anxiety… ‘On the blockers I broke my wrist twice, my knuckles, my toe. It really ruins your bone density.’ Four broken bones in just a few years…As Jacob’s health deteriorated and his puberty continued to ‘break through’, he grew increasingly distressed…After more than four years on the blocker, Jacob felt worse than he ever had before the medication. While his friends were getting their first boyfriends and girlfriends, experiencing their first kisses and sexual experiences, he felt nothing. ‘You have no desire, no drive whatsoever,’ he says. ‘You don’t even feel attracted to people.’ … Emotionally, he felt years younger than his peers. Michelle noticed it too. And physically, Jacob had stopped growing.

The Thirty-three Rules • Every negotiation is an agreement between two or more parties with all parties having the right to veto—the right to say “no.” • Your job is not to be liked. It is to be respected and effective. • Results are not valid goals. • Money has nothing to do with a valid mission and purpose. • Never, ever, spill your beans in the lobby—or anywhere else. • Never enter a negotiation—never make a phone call—without a valid agenda. • The only valid goals are those you can control: behavior and activity. • Mission and purpose must be set in the adversary’s world; our world must be secondary. • Spend maximum time on payside activity and minimum time on nonpayside activity. • You do not need it. You only want it. • No saving. You cannot save the adversary. • Only one person in a negotiation can feel okay. That person is the adversary. • All action—all decision—begins with vision. Without vision, there is no action. • Always show respect to the blocker. • All agreements must be clarified point by point and sealed three times (using 3+). • The clearer the picture of pain, the easier the decision-making process. • The value of the negotiation increases by multiples as time, energy, money, and emotion are spent. • No talking. • Let the adversary save face at all times. • The greatest presentation you will ever give is the one your adversary will never see. • A negotiation is only over when we want it to be over. • “No” is good, “yes” is bad, “maybe” is worse. • Absolutely no closing. • Dance with the tiger. • Our greatest strength is our greatest weakness (Emerson). • Paint the pain. • Mission and purpose drive everything. • Decisions are 100 percent emotional. • Interrogative-led questions drive vision. • Nurture. • No assumptions. No expectations. Only blank slate. • Who are the decision makers? Do you know all of them? • Pay forward.

In late fall, I had a phone sessions with my Oregon therapist. For some reason, we started talking about happiness. “Chris achieved happiness so easily,” I said to him. “And I don’t.” The counselor interrupted me. “Do you know how he did?” I started to answer that I didn’t. But then I realized that Chris had set out to do many things, and he’d achieved them. He’d wanted to be a rodeo competitor, work as a cowboy, join the SEALs. He’d done all of those. What’s more, he excelled at them. Those achievements made him happy, or at least confident enough that he could be happy. As we talked, the counselor noted that I, too, had my own achievements. But I told him--as he already knew--that I wanted to do so many more things. And I always do. Was that a reason not to be happy? The counselor pointed out that I tend to focus on what I haven’t done, rather than what I’ve achieved. My thinking runs; If I do A, then B, then C, then I’ll be happy. But when I achieve A, rather than saying “Yay!” I say, “I haven’t done B and C, so I can’t be happy.” Why focus on what I haven’t done? Why not celebrate those things I have done, even as I look forward to doing other things on my list? Those achievements are accomplishments--I should feel good about them, confident I can do more. And happy. Or at least happier. Another lesson. There are other components to happiness beyond achievement. “Smaller” things, like carving out time for workouts as well as the kids, are actually big things when they are added up. Yet I often feel those things are distractions from what I really want to achieve. Blockers, rather than stepping-stones. Obviously, the wrong way to think about them. On paper, it doesn’t seem like a very profound realization. But put into practice, it means that I--we, all of us--have to keep things in the larger perspective. If you want to achieve a lot, then the reality is that you are always going to have something else you want to do. Keep trying to achieve, but don’t beat yourself up for not getting everything done. The “smaller” things are just as essential to happiness. So: the key to my happiness is appreciating what I have and what I’ve done, and realizing that I’ll always have something else to do. Profound? No, but empowering. I might never have realized it had I not been grieving so deeply. I would have felt silly, really, talking about achieving happiness when Chris was alive. Why wouldn’t I be happy with a great husband and wonderful children? I was happy. But not at the deepest level. I’m not there yet, obviously. But it is possible now. And yet I still wonder: How can I possibly be happy with Chris gone?

Like a beta-blocker, confidence acts as a neurochemical antidote that allows them—allows each of us—to move forward even when we are feeling the physical and psychological manifestations of pressure.

The most effective protection against unwanted adware is the use of pop-up blockers in web browsers. Many pop-up blockers support lists of URLs that allow pop-ups.

constrict cutaneous muscle and splanchnic vasculature and promote salt and water retention. h e synthesis of vasodilating prostaglandins (prostacyclin and PGE 2 ) and nitric oxide in the kidneys and the intrarenal action of angiotensin II recurrent angina signals the need for angiography, if it has not already been performed. Intraaortic balloon counterpulsation is usually reserved for hemodynamically compromised patients with refractory ischemia. Temporary pacing following AMI is indicated for Mobitz type II and complete heart block, a new bifascicular block, and bradycardia with hypotension. Emergency treatment of arrhythmias constantly evolves and we recommend that the guidelines for Advanced Cardiac Life Support be followed. In general, ventricular tachycardia, if treated medically is best managed with amiodarone (150 mg intravenous bolus over 10 min). Synchronized cardioversion may be used in patients with ventricular tachycardia and with a pulse. Patients with a stable narrow-complex supraventricular tachycardia should be treated with amiodarone. Patients with paroxysmal supraventricular tachycardia, whose ejection fraction is preserved, should be treated with a calcium channel blocker, a β blocker, or DC cardioversion. Medically unstable hypotensive patients should receive cardioversion. Patients with ectopic or multifocal atrial tachycardia should not receive DC cardioversion; instead they should be treated with calcium channel blockers, a β blocker, or amiodarone. Acute Kidney Injury & Failure Acute kidney injury (AKI) is a rapid deterioration in renal function that is not immediately reversible by altering factors such as blood pressure, intravascular volume, cardiac output, or urinary l ow. h e hallmark of AKI is azotemia and frequently oliguria. Azotemia may be classii ed as prerenal, renal, and postrenal.Moreover, the diagnosis of renal azotemia is one of exclusion; thus, prerenal and postrenal causes must always be excluded.However, not all patients with acute azotemia have kidney failure.Likewise, urine output of more than 500 mL/d does not imply that renal function is normal. Basing the diagnosis of AKI on creatinine levels or an increase in blood urea nitrogen (BUN) is also problematic because creatinine clearance is not always a good measure of glomerular i ltration 12 r a t e . h e criteria developed by the Acute Kidney Injury Network are now most ot en used

A Sun-Blocker Rotation Trellised tomatoes, beans, peas, and cucumbers, along with corn, can grow 8 to 10 feet tall. To avoid these taller plantings casting shade on other crops, keep these in one rotation on the northeastern side of the garden.

Q: After your prostate is removed because of cancer, what happens to you? A: [he first discusses the surgery itself]… Anyway, I can tell you that it made a big difference in my mental outlook. I found that I thought with my emotions. In my “normal” phase my thinking is a fairly dry, dispassionate affair. I cogitate, mull it over, think about whatever. Under the influence of the hormone blocker, I was shocked at the difference. Every thought had an emotional response tied up with it somehow. It seemed to me that the emotion was the thought. It wasn’t so much that I got emotional about a thought I was having. The emotion and the thought were one and the same. No, more than that: the emotion was the more important part. I didn’t like it.

Hopefully, by this point in the book, you’re on board with the importance of Commercial Insight to any Mobilizer engagement effort. It’s central as well to the process of qualifying Mobilizers. The first step in this exercise is to lead with a thought-provoking insight and gauge the customer’s reaction to it. Remember, Commercial Insight is the Mobilizer dog whistle—only they can hear it and only they will understand the potential it holds for their organizations. This is what you’re looking for right off the bat—engagement around the insight you’ve just put on the table. You’ve approached the customer with an insight or set of insights that teaches them something new and changes the way they think about their business. Done well, this is a provocative insight—provocative because it challenges the customer’s current worldview, the mental model they have about how things are supposed to work. It’s not unlike what you might see in one of those detective shows. The detectives have the suspect in the interrogation room . . . warming him up with some softball questions and then . . . BOOM!—they drop a critical piece of information on the suspect just to gauge his reaction. Just like a master detective, that’s what we’re looking for. We want to gauge our stakeholder’s reaction to our Commercial Insight. If you approach the customer with valuable insight, how do they react? Do they tune you out, or do they stay engaged? Someone who doesn’t even engage with the content of your teaching is almost certainly unlikely to drive change around that idea across the customer organization. If they don’t engage at all, or simply accept the insight at face value, chances are pretty good you’re dealing with either a Blocker (we’ll talk more about how to handle Blockers later in the book), who’s likely against the idea, or a Friend or a Guide, who is never going to dig deep enough to forge consensus around the idea.

Karen snatches a glass of wine from Firestar's hand. Firestar protests, “Why can't I have some mum?” Karen retorts, “Not until you are twelve!” Then Karen hands the wine to Iniesta who sticks her tongue out at Firestar.

Magnesium is the natural element your body uses to prevent excess calcium from entering these cells and to maintain normal blood pressure. Magnesium is indeed our natural calcium blocker. Dr. Sherry Rogers, a leading proponent of integrative medicine, has written extensively about magnesium’s benefits for disorders caused by abnormal muscle constriction. “In order for a muscle to contract, it needs calcium. In order to relax it needs magnesium.”11 Hypertension is one of the conditions for which Dr. Rogers uses magnesium. Magnesium is also necessary for the health of the endothelium, the tiny cells that form the thin inner lining of the blood vessels. Endothelial cells play an active role in prompting the smooth muscle cells to constrict or relax by producing substances such as prostacycline, thromboxane, and endothelin. Magnesium increases the endothelium’s production of prostacycline, which induces artery relaxation, and it inhibits the production of thromboxane and endothelin, which promotes artery constriction.12 Magnesium also directly influences the ability of cells to use potassium, which also induces artery relaxation. Dr. Mildred Seelig, one of the first pioneers of magnesium research, states, “Low potassium, by itself, can bring on high blood pressure. But even adequate potassium intake cannot normalize high blood pressure if magnesium is too low. Without enough magnesium (and potassium) in our bodies, we cannot expect normal blood pressure.”13 THE PROBLEM WITH THE STANDARD MEDICAL TREATMENT OF HYPERTENSION With the exception of the common cold, hypertension accounts for more visits to doctors in the United States than any other condition. Most often, the treatment recommended is some type of prescription drug. Sometimes these drugs are necessary, and there is no doubt their ability to lower blood pressure can prevent many of the severe complications of hypertension.

In addition, some medications can directly affect desire or they can lead to difficulties achieving orgasm, which is a problem in itself and may also in turn reduce desire. These medications include (but are not limited to) many antidepressants, spironolactone, beta blockers, trazodone (a sleep aid), and opioids.

Brave applies a two-pronged strategy to this problem. It has created a new browser designed to work seamlessly with its tokens. The browser blocks all ads by default and, with sophisticated analytics, collates and anonymizes data from users that indicate how much time they spend looking at certain content. That way it can come up with a useful record of the amount of time we all spend at Internet sites without identifying us. As a user of the Brave browser, you are offered the potential to earn BATs for selectively turning off the ad blocker to view ads; tokens are delivered to an integrated wallet that you uniquely control. You can in turn use those tokens to reward publishers of content that you appreciate—in effect, tipping them with donations. Meanwhile, to place ads with publishers of content on the system, advertisers must first acquire BATs and then pay those tokens to publishers, with the price for those ads dictated by the attention metrics associated with the latter’s content.

If Dulac is right about the link between these urocortin neurons and postpartum depression, she hopes that her work can help identify drugs that could act as blockers to treat such disorders.

Shkreli’s money-making strategy was to forget about investing in new medicines, and instead to buy existing ones on the cheap, hike their prices and restrict their supply. Turing started out with three drugs – ketamine for depression, oxytocin to induce labour and a ganglionic blocker for hypertension – all acquired from Retrophin. On 10 August 2015, Turing bought Daraprim for $55 million. The very next day, it executed the 5,500% price increase.

If a bug is found, the first question is “Is this a blocker?” Blocker in this case means “The feature won’t be releasable with this bug” or “This bug is more important to fix than building additional features.

Most vertebrates and all of our fellow mammals have similar chemical and neurological mechanisms that transmit and control pain. Under stress or trauma, they display physiological reactions identical to ours - increased heartbeat and perspiration, higher cortisone levels in the blood, a release of endorphins, serotonin, and other natural opiates. Their bodies respond to anesthesia just as our bodies do, and of course they display vocalizations, defensive behavior, and bodily contortions similar to ours. We may add to this physical evidence the fact that veterinarians today routinely prescribe exactly the same antidepressant drugs to dogs, cats, pigs, horses and other animals, including Prozac, Ritalin, Xanax, and beta-blockers, and these drugs have exactly the same soothing effects on them as on us.

For example, a March 2021 study18 by Choudhury et al., found that “Ivermectin was found as a blocker of viral replicase, protease and human TMPRSS2, which could be the biophysical basis behind its antiviral efficiency.” The drug also reduces inflammation via multiple pathways, thereby protecting against organ damage. Ivermectin furthermore impairs the spike protein’s ability to attach to the ACE2 receptor on human cell membranes, preventing viral entry. Moreover, the drug prevents blood clots through binding to spike protein, and also deters the spike protein from binding to CD147 on red blood cells, which would otherwise trigger clumping. When patients take IVM before exposure, the drug prevents infection, which halts onward transmission, and helps protect the entire community.

What if every member of the company were asked to create a daily learning goal and to report on what you learned during standup along with blockers and tasks? What if this learning goal is something that each person can do in fifteen minutes or less and could be achieved on their own without the help of another team member?

Cunt-punter is female for cock-blocker, by the way.

There are UV blockers that you can add to your soy candles if this is a problem for you, or if you’re selling your candles and want them to stay pristine-looking long term to keep your customers happy. For personal use, you can also just keep soy candles out of direct sunlight to minimize discoloration.

Presenting data from numerous studies, Susan Pinker offers a compelling argument that the strength of our social relationships is comparable to well established risk factors for mortality such as smoking and alcohol consumption. Weak social relationships are a more significant risk factor than physical inactivity and obesity. Simply playing cards once a week or meeting friends every Wednesday night at Starbucks adds as many years to our lives as taking beta blockers or quitting a pack a day smoking habit. The subtitle of her book, “how face to face contact can make us happier healthier and smarter” gets the point across: if we don’t interact regularly with people face-to-face, the odds are that we won’t live as long, remember the information as well, or be as happy as we otherwise could have been. The solution is no doubt multifaceted it will involve a variety of tactics, including the themes spelled out in the remaining pages of this book: the art of neighboring, restoring genuine community, sharing meals with others, welcoming the stranger, opening our lives and those who are disconnected.

Its next product was a different style of blue-blocker glasses, and it bombed. What happened? Well, James had bought into the belief that he was selling glasses, not helping people with sleep problems. He had focused on the product, not the person. He needed to discover that he was a sleep company, not a glasses company. Once that was solved, it was easy to come up with three to five new products that the company could sell. That changes everything. It’s tempting to fall into the trap that your business sells products, because that’s where the money comes from. But products are bought by people, and you must know who they are if you want to hit a million dollars.

they tend to be very powerful. Their abilities offer incremental advantage every turn so they favour a long game and a stalemated board. As they are attackable directly, like players, then playing one without adequate blockers will see them getting killed before you can gain sufficient benefit.

Beans, whole grains, and garden vegetables are the cornerstones of all these longevity diets. Sardinian shepherds take semolina flatbread into the pastures with them. Nicoyans eat corn tortillas at every meal. And whole grain is part of the Adventist diet. Whole grains deliver fiber, antioxidants, potential anti-cancer agents (insoluble fiber), cholesterol reducers, and clot blockers, plus essential minerals. Beans (legumes) also provide a cornerstone to Blue Zone meals. Diets

It took the wind out of me,’ one senior staff member at the time tells me. And made them furious. The Executive had found time to write papers about ‘postmodernist, high-level theoretical ideas and stuff’, they explain, but the service was not following up the children and young people it had cared for. GIDS could not even tell the High Court how many of the young people put on blockers were autistic, they say, in despair. ‘We don’t fucking care about post-structuralist ideas.

Doctors know that cross-sex hormones (immediately after puberty blockers) make children permanently sterile. The doctors did not share this information with parents or children.42 Another disturbing aspect of the center was its lack of regard for the rights of parents—and the extent to which doctors saw themselves as more informed decision-makers over the fate of these children.43

For excess hair: Women may be successfully treated with metformin, spironolactone, birth control pills, and/or oral estrogen. Spironolactone somehow produces more healthy hair growth for them. It can both improve scalp hair thickness and decrease excess hair. It is a mild diuretic, anti-inflammatory, and testosterone blocker.

I knew why I loved that painting. I was on that raft. Dante was on that raft. My mother and Dante's mom and dad and Cassandra and Susie and Gina and Danny and Julio and Mr. Blocker. And Mrs. Livermore and Mrs. Alvidrez, they were on that raft too. And those who had died too soon-- my dad and my aunt Ophelia and Cassandra's brother, and Emma's son and Rico, and Camila, all the lost people that the world had thrown away- they were there with us on that raft, and their dreams and desires too. And if the raft collapsed, we would dive into the waters of that stormy sea- and swim our way to shore.

Is the Bullet Blocker NIJ IIIA Sprout Backpack a “failure of imagination,” or simply the natural extension of a eugenic imagination that displaces deadly social problems onto individuals, asking the most vulnerable to literally shoulder the problem?

there is no such thing as individual achievement. A quarterback throws an interception and it might be his own fault; but it might also be the fault of the receiver who ran the wrong route, or the blocker who allowed him to be hit as he threw. Twenty-two players are involved in every football play. To value precisely the activity of any one of them, i

He looks skinny, wears brown, tortoiseshell glasses that don’t actually look prescription. They look like blue-blockers—glasses made for people who wish they had glasses. Strike one.

When you’re trying something new, the idea that you should only begin when you feel confident to begin is a blocker all of its own. The solution? Just do it, even if you feel like you’re doing it badly. Make a start. You won’t need to get perfect for a long time yet.

In one Globetrotter’s skit, it involved Globetrotter’s Captain Meadowlark Lemon collapsing on the ground, and Wilt threw him up in the air several feet high and caught him like a baby. Lemon weighed 210 lbs. Lemon, and other people including Arnold Schwarzenegger, said that Wilt was the strongest athlete that ever lived. On March 9, 2000, his number 13 was retired by the Globetrotters. Wilt’s NBA Career Accomplishments On October 24, 1959 Wilt finally made his NBA debut. Wilt played for the then, “Philadelphia Warriors.” Wilt immediately became the league’s top earner making $30,000 topping Bob Cousy who was making $25,000. The $30,000 is equivalent to $263,000 in today’s currency as per the year 2019. In Wilt’s 1959-1960 season, which was his rookie year, his team made the playoffs. The Warriors beat the Syracuse Nationals then had to go on to play the Eastern Conference Champions, the Boston Celtics. Coach Red Auerbach strategized his forward Tom Heinsohn to commit fouls on Wilt. When the Warriors shot free throws, Heinsohn grabbed and pushed Wilt to stop him from getting back on defense, so quickly. Wilt was a prolific shot blocker, and this allowed Celtics to score quickly without Wilt protecting the basket. The Warriors lost the series 4 games to two after Tom Heinsohn got a last second tip in to seal the win of the series for the Celtics. As a rookie Wilt shocked Warriors' fans by saying he was thinking of retiring from basketball. He was tired of being double- and triple-teamed, and of teams fouling him very hard. Wilt was afraid that he would lose his temper one day which he did in the playoff series versus Boston. Wilt punched Heinsohn and injured his hand. Wilt played for The Philadelphia Warriors, who then relocated to San Francisco, The Philadelphia 76ers, and The Los Angeles Lakers. He won one title with the 76ers then one with the Lakers. First NBA game Wilt scored 43 points and snatched 28 rebounds. Grabbed his rookie career high of 43 rebounds in a win over the New York Knicks.

We do a visualization exercise with one of the sports psychologists on the team,” he says, studying me. “She has me picture the game. I imagine the other team’s forwards trying to score on me and what the puck feels like in my glove or hitting my blocker. I picture each of their guys and every scoring configuration I can think of. The more specific I am, the better.” He arches his brow. “I think you should try that, but with music.

Why is there a perseveration on gender instead of expanding inquiry and addressing all dimensions of a being in distress? Why are we enabling kids to possibly run from something such as past trauma or encouraging distraction from emotional pain by quickly writing a prescription for puberty blockers or a cross-sex hormone on the first or second visit to a clinic?

Ivermectin was found as a blocker of viral replicase, protease and human TMPRSS2, which could be the biophysical basis behind its antiviral efficiency.” The drug also reduces inflammation via multiple pathways, thereby protecting against organ damage. Ivermectin furthermore impairs the spike protein’s ability to attach to the ACE2 receptor on human cell membranes, preventing viral entry. Moreover, the drug prevents blood clots

We’ve been using these drugs for years,” Rosie the clinician explained, “to put a stop to what’s called Precocious Puberty. Sometimes we’ll see a little girl who has breast buds at six or a first-grade boy whose testes have already enlarged or who’s already sprouted pubic hair. These kids go on hormone blockers. The drug puts them on hold. It buys them time for everyone else to catch up. Then, when they reach the age of nine or ten, we take them off the blockers,

Changes her mind?” Penn interrupted. “—because as soon as you take them off the hormone blockers, patients’ bodies proceed normally through their natal puberty.” “But.

When confronted with sensory dread, it can be helpful to prepare yourself in advance by using sensory blockers, having an exit plan to take sensory breaks, and limiting the amount of high-sensory tasks in your day. For anxiety, you can try unhooking from unhelpful thoughts, practicing relaxation techniques, and challenging avoidance patterns.

Hour of Power One of my favorite things is starting my day with my morning Hour of Power. It’s an hour that I set aside every morning, first thing in the morning, to reflect, review, and recommit to my goals. I take this time to train my mind and reconnect with who I want to be.

You can design your hour of power (or 35 minutes or 45 minutes) to be what you need to perform at your best. With your hour of power, you can start your day strong, organized, and tracking toward your goals, starting by reconnecting to what matters most.  Here are some things you can schedule in your Hour of Power: • Goal Review: Review the goals that you’ve set for yourself and reconnect to what it feels like to have achieved that goal. Cover the delta between where you are now and where you need to be to achieve your goals.

Reconstructive surgeon and ‘world-renowned vaginoplasty specialist’ Marci Bowers voiced concerns over blocking puberty too early in those born male. Not only can surgery be more difficult because of lack of penile tissue to use (a warning that GIDS clinicians had been issued in 2016 and the Dutch team have discussed), but those children would not be able to achieve orgasm as adults. ‘If you’ve never had an orgasm pre-surgery, and then your puberty’s blocked, it’s very difficult to achieve that afterwards…I consider that a big problem, actually. It’s kind of an overlooked problem that in our “informed consent” of children undergoing puberty blockers, we’ve in some respects overlooked that a little bit.

GIDS’s own limited data, which found ‘no evidence of change in psychological function’ with puberty-blocker treatment.

In fact, a widely used drug in nightmares associated with PTSD, prazosin, acts mainly as a blocker of noradrenaline in the brain. Although a recent study suggests prazosin is no more effective than a placebo, I and my colleagues have seen several patients successfully treated with this drug.

In hundreds of . . . cases, Center doctors automatically issued puberty blockers or cross-sex hormones without considering the child’s individual circumstances or mental health.16

Things get in the way,' she said, 'that's what's sad about life.

Safetyism was imposed on the millennials beginning slowly in the 1980s and then more quickly in the 1990s.[5] The rapid deterioration of mental health, however, did not begin until the early 2010s and was concentrated in Gen Z, not among millennials.[6] It was not until the addition of the second experience blocker—the smartphone—that rates began to rise.

THE FOUR PRACTICES OF THE TALENT MAGNET Among the Multipliers we studied in our research, we found four active practices that together catalyze and sustain this cycle of attraction. These Talent Magnets: 1) look for talent everywhere; 2) find people’s native genius; 3) utilize people at their fullest; and 4) remove the blockers.

He hands her his pack, which he’s emptied. “You mean me?” Justineau demands. “You think I’m not pulling my weight?” It would feel good to have a stand-up argument with Parks right then, but he doesn’t seem keen to play. “No, I didn’t mean you. I meant in general.” “People in general? You were being philosophical?” “I was being a grumpy bastard. It’s what I wear to the office most days. I guess you probably noticed that.” She hesitates, wrong-footed. She didn’t think Parks was capable of self-deprecation. But then she didn’t think he was capable of changing his mind. “Any more rules of engagement?” she asks him, still hurting in some obscure way, still not mollified. “How to survive when shopping? Top tips for modern urban living?” Parks gives the question more consideration than she was expecting. “Use up the last of that e-blocker,” he suggests. “And don’t die.

Opioid Use Disorders There are several medications approved for use with opioid users. These fall into two categories: 1) blocking the effects of opioids, and 2) replacing the abused opioid with a different, longer-acting opioid for maintenance on that medication. Opioid replacement or maintenance therapy has a long and documented history of effectiveness and safety. Opioid blocking medications, while basically safe, have been poorly received by the client community. We hope that the effectiveness profile of blockers changes with the advent of new, long-acting (one-month) injectable blockers (Vivitrol), but evidence is still being collected. Blockers: Naltrexone/Vivitrol: This blocks opioid receptors (yes, the same naltrexone from the alcohol category, but used for opioids for an entirely different effect). Naltrexone is given daily and orally and therefore has compliance problems because people can simply stop taking the medication and get high within a couple of days. Vivitrol, an injectable form of naltrexone that blocks opioid receptors for one month, is showing promising results in improving compliance. This

All the questions we seek, we possess the answers to. Fear is our normal and typical blocker of all things wonderful within us.

Screw being impressed by the fact that the entire cemetery rose to ruin his attempts to get into the girl’s pants. Fucking undead cock blockers. He found himself even less impressed by the fact that they were more interested in her brain than his.

And then there is Apple, the dissenter from the libertarian creed. Both Steve Jobs and Tim Cook have been real allies to the content community, and their stance against the surveillance-marketing model that is at the core of Google’s and Facebook’s businesses—i.e., their support of ad blockers—puts them in direct opposition to the dominant search and social platforms.

You get the culture you pay for.” As we work on technology migration with enterprises, it’s usually people and processes that are the blockers, not technology problems.

We know we can prevent heart attacks with aspirin, and with drugs called beta-blockers. We know that certain. Lange

meetings can be used to stay ahead, flagging issues before they become blockers.

3.5 A 45-year-old woman is noted to have dizziness, pounding of the chest, and fatigue of 3 hours’ duration. On examination, she is noted to have a blood pressure (BP) of 110/70 mm Hg and heart rate of 180 bpm. She is noted on ECG to have atrial fibrillation, and a prior baseline ECG showed delta waves. The ER physician counsels the patient regarding cardioversion, but the patient declines. Which of the following is the best therapy for her condition? A. Digoxin B. Angiotensin-converting enzyme (ACE) inhibitor C. Calcium channel blocker D. Procainamide

If I’d known we were just going to sit around and watch the plants grow today, I would have brought my book.” Emma jerked her attention from the columbine plants she’d been checking on and back to Sean. “Sorry. Zoned out for a minute. Did you get the weed blocker done?” “Yeah. I don’t get why they want the pathway to the beach done in white stone. Don’t you usually walk back from the water barefoot?” “Not this couple. It doesn’t matter how practical it is. All that matters is how it looks.” “Whatever. It’s going to take the rest of the day to get all that stone down, so stop mentally tiptoeing through the tulips and let’s go.” Emma wanted to tell him to shove his attitude up his ass, because she was the boss, or at least flip him the bird behind his back, but she didn’t have the energy. Living a fake life was a lot more exhausting than she’d anticipated. She didn’t even want to think about what it was like trying to sleep every night with her boxer-brief-clad roommate sprawled across the bed only ten feet away, so she thought about Gram instead. Gram, who was, at that very moment, on her way into town. The town that had heard the rumors of her engagement, but never actually seen her fiancé. If Gram returned from town still believing Emma and Sean were headed to the altar, it would be a miracle.

But it is not the remembrance of his athletic ability that—fifty years later—makes San Marcos students smile when they remember the stalwart Boody Johnson. “He was the fatherly type,” a football player says. “If things were going bad in a game, he’d call a time-out, and gather the team around, and say, ‘Now, look, fellows, we’re here to play football,’ and settle everybody down.” He didn’t settle down only football players. “You always felt you could go to him with your problems,” says one woman. “He was a very kind person. Gruff and tough, but very kind. He was just like a father to everybody.” His unselfishness was legendary, and not just on the football field (where, because the other halfback, Lyons McCall, a good runner, was a poor blocker, Boody volunteered to do most of the blocking while McCall carried the ball—if the team was behind in the last minutes of a game, however, the players would growl: “Give it to Boody”). “Boody was the kind of guy who, if you woke him up in the middle of the night and told him your car had broken down, would get out of bed and walk five miles to help you—nothing was too much trouble for him,” Vernon Whiteside says.

initially, pain is a warning system, but if it becomes chronic, it turns into something else: a sort of continual feedback loop. “Many people eventually stop coding the danger signal. But some people don’t seem to,” he says. “It’s a problem of accepting, coding, interpreting, and responding.” In other words, prediction. Expectation. No one told the brain that it’s no longer in danger, so it keeps expecting danger and warning the body. This is why anxiety, depression, and stress are so closely linked to chronic pain. The game becomes finding ways to tell the brain it’s OK to relax, even if that means tricking it. Mackey and other pain doctors can do this using pain blockers that stop the warning messages from transmitting, thus forcing the brain to realize it’s no longer in pain.† So is there a way to enhance the placebo effect, even make it permanent?

In a classic enterprise sale, you will often have a strategic buyer (who is excited about the change you can bring), an economic buyer (who controls the purse), a technical buyer (who might have approval/blocker rights), and then the actual users of your product. Can you identify your champion? Can you identify who might be a saboteur?

chemopreventive” (cancer-preventing) activity. Only a few dozen have made it to clinical trials, but among the most promising is curcumin, the bright-yellow pigment in turmeric.12 Chemopreventive agents can be classified into different subgroups based on which stage of cancer development they help to fight: Carcinogen blockers and antioxidants help prevent the initial triggering DNA mutation, and antiproliferatives work by

If you could learn entire languages in a week, draw perfect pictures without thinking about it, and make complex calculations in your head in seconds, would you be willing to trade that for the ability to comfortably walk into a coffee shop and shake a stranger’s hand? My thoughts went racing to modern comic mythology such as X-Men: The Last Stand, in which mutants are presented with a drug that could make them normal by robbing them of their powers. Would purine treatment in autistic savants be the same sort of thing? I had to know, so I asked Dr. Naviaux, “Will savants lose their mutant powers if we cure them? “Treating an autistic savant with a purine inhibitor should not change his or her extraordinary abilities at all,” he said. The hyperconnected islands of neurons that were formed when an autism patient was young would still be there. The powers that the islands grant would still be available, but they would no longer be the only neural connections available. “In younger patients in particular, new connections, longer ones, stand a good chance of forming once the danger response is shut down by a purine blocker,” says Dr. Naviaux. The result? A superhuman mind without the burden of autism. Wow.

They’re called intimacy blockers because if you’re keeping a secret from someone, about something you did or that somebody else did, whichever, then you’re not in an honest relationship with them.

I told my inner-Dr. Phil to slow his fucking role.

and they wore thick white liner around their green eyes. Monti recognized the makeup as a way to avoid the cams the First Order employed. He noticed a white scarf coiled around their neck, big enough to pull up over mouth and nose, another facial recognition blocker.

Another class of drugs that is disastrous for your gut is proton pump inhibitors (PPIs) and other stomach acid reducers such as Zantac, Prilosec, Nexium, and Protonix. Stomach acid is important and necessary. It kills off most of the bad bugs you swallow before they make it to your gut. Without enough of it, bad bugs—including those that can cause infectious diseases—can take over. This is why people who regularly use acid blockers are three times more likely to get pneumonia than those who don’t use them;9 stomach acid is one of the best defenses against bad bugs getting into you, as one of its main purposes is to kill bacteria. Also, remember that lectins are plant proteins; stomach acid is designed to digest proteins. So by using stomach acid blockers, you inadvertently wipe out one of your major defense mechanisms against lectins!