Antonio Damasio Quotes

We all woke up this morning and we had with it the amazing return of our conscious mind. We recovered minds with a complete sense of self and a complete sense of our own existence — yet we hardly ever pause to consider this wonder.

neuroscientist Antonio Damasio reminds us, “We are not necessarily thinking machines. We are feeling machines that think.

The self is a repeatedly reconstructed biological state.

WE ALMOST NEVER think of the present, and when we do, it is only to see what light it throws on our plans for the future.

Perhaps the most indispensable thing we can do as human beings, every day of our lives, is remind ourselves and others of our complexity, fragility, finiteness, and uniqueness.

...I sense that stepping into the light is also a powerful metaphor for consciousness, for the birth of the knowing mind, for the simple and yet momentous coming of the sense of self into the world of the mental.

We use our minds not to discover facts but to hide them. One of things the screen hides most effectively is the body, our own body, by which I mean, the ins and outs of it, its interiors. Like a veil thrown over the skin to secure its modesty, the screen partially removes from the mind the inner states of the body, those that constitute the flow of life as it wanders in the journey of each day. (p.28)

As neuroscientist Antonio Damasio reminds us, humans are not either thinking machines or feeling machines, but rather feeling machines that think.

Leaving out appraisal also would render the biological description of the phenomena of emotion vulnerable to the caricature that emotions without an appraisal phase are meaningless events. It would be more difficult to see how beautiful and amazingly intelligent emotions can be, and how powerfully they can solve problems for us.

I do not see emotions and feelings as the intangible and vaporous qualities that many presume them to be. Their subject matter is concrete, and they can be related to specific systems in body and brain, no less so than vision or speech.

Present continuously becomes past, and by the time we take stock of it we are in another present, consumed with planning the future, which we do on the stepping-stones of the past. The present is never here. We are hopelessly late for consciousness.

When emotion is entirely left out of the reasoning picture, as happens in certain neurological conditions, reason turns out to be even more flawed than when emotion plays bad tricks on our decisions.

Neuroscientist Antonio Damasio describes emotions as the “continuous musical line of our minds, the unstoppable humming.”3

The immune system, the hypothalamus, the ventro-medial frontal cortices, and the Bill of Rights have the same root cause.

most of our decision making was shaped by somatic states related to punishment and reward. But

Neither anguish nor the elation that love or art can bring about are devalued by understanding some of the myriad biological processes that make them what they are. Precisely the opposite should be true: Our sense of wonder should increase before the intricate mechanisms that make such magic possible. Feelings form the base for what humans have described for millennia as the human soul or spirit.

At each moment the state of self is constructed, from the ground up,” writes Antonio Damasio. “It is an evanescent reference state, so continuously and consistently reconstructed that the owner never knows it is being remade unless something goes wrong with the remaking.

The brain that we think of as a necessity for intelligence is only one possible form a neural network can take and that is determined by ecological function and species shape; it is not essential to intelligence. As neurologist Antonio Damasio puts it, “the mind is embodied, not just embrained.

Para mi es imposible pensar que tipo de emocion de miedo quedaria si no estuvieran presentes la sensacion de latidos acelerados o de respiracion entrecortada, ni la sensacion de labios temblorosos o de piernas debilitadas, ni de carne de gallina o de retorcijones de tripas. Puede alguien imaginarse el estado de ira sin sentir que el pecho estalla, la cara se ruboriza, los orificios nasales se dilatan, los dientes se aprietan, sin notar el impulso hacia la accion vigorosa? Puede sentirse rabia en cambio con los musculos relajados, la respiracion calmada y una cara placida?

Throughout the human life span there remains a constant two-way interaction between psychological states and the neurochemistry of the frontal lobes, a fact that many doctors do not pay enough attention to. One result is the overreliance on medications in the treatment of mental disorders. Modern psychiatry is doing too much listening to Prozac and not enough listening to human beings; people’s life histories should be given at least as much importance as the chemistry of their brains. The dominant tendency is to explain mental conditions by deficiencies of the brain’s chemical messengers, the neurotransmitters. As Daniel J. Siegel has sharply remarked, “We hear it said everywhere these days that the experience of human beings comes from their chemicals.” Depression, according to the simple biochemical model, is due to a lack of serotonin — and, it is said, so is excessive aggression. The answer is Prozac, which increases serotonin levels in the brain. Attention deficit is thought to be due in part to an undersupply of dopamine, one of the brain’s most important neurotransmitters, crucial to attention and to experiencing reward states. The answer is Ritalin. Just as Prozac elevates serotonin levels, Ritalin or other psychostimulants are thought to increase the availability of dopamine in the brain’s prefrontal areas. This is believed to increase motivation and attention by improving the functioning of areas in the prefrontal cortex. Although they carry some truth, such biochemical explanations of complex mental states are dangerous oversimplifications — as the neurologist Antonio Damasio cautions: "When it comes to explaining behavior and mind, it is not enough to mention neurochemistry... The problem is that it is not the absence or low amount of serotonin per se that “causes” certain manifestations. Serotonin is part of an exceedingly complicated mechanism which operates at the level of molecules, synapses, local circuits, and systems, and in which sociocultural factors, past and present, also intervene powerfully. The deficiencies and imbalances of brain chemicals are as much effect as cause. They are greatly influenced by emotional experiences. Some experiences deplete the supply of neurotransmitters; other experiences enhance them. In turn, the availability — or lack of availability — of brain chemicals can promote certain behaviors and emotional responses and inhibit others. Once more we see that the relationship between behavior and biology is not a one-way street.

somatic markers depend on learning within a system that can connect certain categories of entity or event with the enactment of a body state, pleasant or unpleasant. Incidentally,

Because the brain is the body’s captive audience, feelings are winners among equals. And

We used to believe that we were thinking beings who just happen to feel. We now know that we are feeling beings who think.

It is not customary to refer to organisms when we talk about brain and mind. It has been so obvious that mind arises from the activity of neurons that only neurons are discussed as if their operation could be independent from that of the rest of the organism. But as I investigated disorders of memory, language, and reason in numerous human beings with brain damage, the idea that mental activity, from its simplest aspects to its most sublime, requires both brain and body proper became especially compelling.

By now you may have concluded that the conversation was neither about Descartes nor about philosophy, although it certainly was about mind, brain, and body. My friend suggested it should take place under the Sign of Descartes, since there was no way of approaching such themes without evoking the emblematic figure who shaped the most commonly held account of their relationship. At this point I realized that, in a curious way, the book would be about Descartes' Error. You will, of course, want to know what the Error was, but for the moment I am sworn to secrecy. I promise, though, that it will be revealed.

What’s more, AI researchers have begun to realize that emotions may be a key to consciousness. Neuroscientists like Dr. Antonio Damasio have found that when the link between the prefrontal lobe (which governs rational thought) and the emotional centers (e.g., the limbic system) is damaged, patients cannot make value judgments. They are paralyzed when making the simplest of decisions (what things to buy, when to set an appointment, which color pen to use) because everything has the same value to them. Hence, emotions are not a luxury; they are absolutely essential, and without them a robot will have difficulty determining what is important and what is not.

What worries me is the acceptance of the importance of feelings without any effort to understand their complex biological and sociocultural machinery. The best example of this attitude can be found in the attempt to explain bruised feelings or irrational behavior by appealing to surface social causes or the action of neurotransmitters, two explanations that pervade the social discourse as presented in the visual and printed media; and in the attempt to correct personal and social problems with medical and nonmedical drugs. It is precisely this lack of understanding of the nature of feelings and reason (one of the hallmarks of the "culture of complaint") that is cause for alarm.

What’s more, AI researchers have begun to realize that emotions may be a key to consciousness. Neuroscientists like Dr. Antonio Damasio have found that when the link between the prefrontal lobe (which governs rational thought) and the emotional centers (e.g., the limbic system) is damaged, patients cannot make value judgments. They are paralyzed when making the simplest of decisions (what things to buy, when to set an appointment, which color pen to use) because everything has the same value to them. Hence, emotions are not a luxury; they are absolutely essential, and without them a robot will have difficulty determining what is important and what is not. So emotions, instead of being peripheral to the progress of artificial intelligence, are now assuming central importance. If a robot encounters a raging fire, it might rescue the computer files first, not the people, since its programming might say that valuable documents cannot be replaced but workers always can be. It is crucial that robots be programmed to distinguish between what is important and what is not, and emotions are shortcuts the brain uses to rapidly determine this. Robots would thus have to be programmed to have a value system—that human life is more important than material objects, that children should be rescued first in an emergency, that objects with a higher price are more valuable than objects with a lower price, etc. Since robots do not come equipped with values, a huge list of value judgments must be uploaded into them. The problem with emotions, however, is that they are sometimes irrational, while robots are mathematically precise. So silicon consciousness may differ from human consciousness in key ways. For example, humans have little control over emotions, since they happen so rapidly and because they originate in the limbic system, not the prefrontal cortex of the brain. Furthermore, our emotions are often biased.

If ensuring the survival of the body proper is what the brain first evolved for, then, when minded brains first appeared, they began by minding the body. And to ensure body survival as effectively as possible, nature, I suggest, stumbled on a highly effective solution: representing the outside world in terms of the modifications it causes in the body proper, that is, representing the environment by modifying the primordial representations of the body proper whenever an interaction between organism and environment takes place.

most students reported a state of total involvement in what was being taught, he would rate the moment “inspired.” The inspired moments of learning shared the same active ingredients: a potent combination of full attention, enthusiastic interest, and positive emotional intensity. The joy in learning comes during these moments. Such joyous moments, says University of Southern California neuroscientist Antonio Damasio, signify “optimal physiological coordination and smooth running of the operations of life.” Damasio, one of the world’s leading neuroscientists, has long been a pioneer in linking findings in brain science to human experience. Damasio argues that more than merely letting us survive the daily grind, joyous states allow us to flourish, to live well, and to feel well-being. Such upbeat states, he notes, allow a “greater ease in the capacity to act,” a greater harmony in our functioning that enhances our power and freedom in whatever we do. The field of cognitive science, Damasio notes, in studying the neural networks that run mental operations, finds similar conditions and dubs them “maximal harmonious states.

As a consequence of natural analgesic actions or as a result of the administration of drugs that interfere with body signaling (painkillers, anesthetics), the brain receives a distorted view of what the body state really is at the moment. We know that in situations of fear in which the brain chooses the running option rather than freezing, the brain stem disengages the part of the pain-transmission circuitry, a bit like pulling the plug. The periqueductal gray, which controls these responses, can also command the secretion of natural opioids and achieve precisely what taking an analgesic would achieve -- elimination of pain signals. In the strict sense, we are dealing here with a hallucination of the body because what the brain registers in its maps and the conscious mind feels do not correspond to the reality that might be perceived. Whenever we ingest molecules the have the power to modify the transmission or mapping of body signals, we play on this mechanism. Alcohol does it; so do analgesics and anesthetics, as well as countless drugs of abuse. It is patently clear that, other than out of curiousity, humans are drawn to such molecules because of their desire to generate feelings of well-being, feelings in which pain signals are obliterated and pleasure signals induced.

The human brain is the most complex entity in the universe. It has between fifty and one hundred billion nerve cells, or neurons, each branched to form thousands of possible connections with other nerve cells. It has been estimated that laid end to end, the nerve cables of a single human brain would extend into a line several hundred thousand miles long. The total number of connections, or synapses, is in the trillions. The parallel and simultaneous activity of innumerable brain circuits, and networks of circuits, produces millions of firing patterns each and every second of our lives. The brain has well been described as “a supersystcm of systems.” Even though fully half of the roughly hundred thousand genes in the human organism are dedicated to the central nervous system, the genetic code simply cannot carry enough information to predetermine the infinite number of potential brain circuits. For this reason alone, biological heredity could not by itself account for the densely intertwined psychology and neurophysiology of attention deficit disorder. Experience in the world determines the fine wiring of the brain. As the neurologist and neuroscientist Antonio Damasio puts it, “Much of each brain’s circuitry, at any given moment in adult life, is individual and unique, truly reflective of that particular organism’s history and circumstances.” This is no less true of children and infants. Not even in the brains of genetically identical twins will the same patterns be found in the shape of nerve cells or the numbers and configuration of their synapses with other neurons. The microcircuitry of the brain is formatted by influences during the first few years of life, a period when the human brain undergoes astonishingly rapid growth. Five-sixths of the branching of nerve cells in the brain occurs after birth. At times in the first year of life, new synapses are being established at a rate of three billion a second. In large part, each infant’s individual experiences in the early years determine which brain structures will develop and how well, and which nerve centers will be connected with which other nerve centers, and establish the networks controlling behavior. The intricately programmed interactions between heredity and environment that make for the development of the human brain are determined by a “fantastic, almost surrealistically complex choreography,” in the apt phrase of Dr. J. S. Grotstein of the department of psychiatry at UCLA. Attention deficit disorder results from the miswiring of brain circuits, in susceptible infants, during this crucial period of growth.

For instance, emotional memories are stored in the amygdala, but words are recorded in the temporal lobe. Meanwhile, colors and other visual information are collected in the occipital lobe, and the sense of touch and movement reside in the parietal lobe. So far, scientists have identified more than twenty categories of memories that are stored in different parts of the brain, including fruits and vegetables, plants, animals, body parts, colors, numbers, letters, nouns, verbs, proper names, faces, facial expressions, and various emotions and sounds. Figure 11. This shows the path taken to create memories. Impulses from the senses pass through the brain stem, to the thalamus, out to the various cortices, and then to the prefrontal cortex. They then pass to the hippocampus to form long-term memories. (illustration credit 5.1) A single memory—for instance, a walk in the park—involves information that is broken down and stored in various regions of the brain, but reliving just one aspect of the memory (e.g., the smell of freshly cut grass) can suddenly send the brain racing to pull the fragments together to form a cohesive recollection. The ultimate goal of memory research is, then, to figure out how these scattered fragments are somehow reassembled when we recall an experience. This is called the “binding problem,” and a solution could potentially explain many puzzling aspects of memory. For instance, Dr. Antonio Damasio has analyzed stroke patients who are incapable of identifying a single category, even though they are able to recall everything else. This is because the stroke has affected just one particular area of the brain, where that certain category was stored. The binding problem is further complicated because all our memories and experiences are highly personal. Memories might be customized for the individual, so that the categories of memories for one person may not correlate with the categories of memories for another. Wine tasters, for example, may have many categories for labeling subtle variations in taste, while physicists may have other categories for certain equations. Categories, after all, are by-products of experience, and different people may therefore have different categories. One novel solution to the binding problem uses the fact that there are electromagnetic vibrations oscillating across the entire brain at roughly forty cycles per second, which can be picked up by EEG scans. One fragment of memory might vibrate at a very precise frequency and stimulate another fragment of memory stored in a distant part of the brain. Previously it was thought that memories might be stored physically close to one another, but this new theory says that memories are not linked spatially but rather temporally, by vibrating in unison. If this theory holds up, it means that there are electromagnetic vibrations constantly flowing through the entire brain, linking up different regions and thereby re-creating entire memories. Hence the constant flow of information between the hippocampus, the prefrontal cortex, the thalamus, and the different cortices might not be entirely neural after all. Some of this flow may be in the form of resonance across different brain structures.

People with a condition called prosopagnosia cannot distinguish between familiar and unfamiliar faces. They rely entirely on cues such as hairlines, gait, and voices to recognize people they know. Pondering this condition led researchers Daniel Tranel and Antonio Damasio to try something clever: even though prosopagnosics cannot consciously recognize faces, would they have a measurable skin conductance response to faces that were familiar? Indeed, they did. Even though the prosopagnosic truly insists on being unable to recognize faces, some part of his brain can (and does) distinguish familiar faces from unfamiliar ones.

Antonio Damasio has written three books: Looking for Spinoza, Descartes’ Error, and The Feeling of What Happens. These

Affect is not just necessary for wisdom; it’s also irrevocably woven into the fabric of every decision. —ANTONIO DAMASIO, NEUROSCIENTIST, UNIVERSITY OF SOUTHERN CALIFORNIA

The neuroscientist Antonio Damasio says such feelings are our wake-up to a problem “that the body has already begun to solve.” The point is: We may already have entered the transition before our mind even realizes it. Here

There’s another level at which attention operates, this has to do with leadership, I argue that leaders need three kinds of focus, to be really effective, the first is an inner focus, let me tell you about a case that’s actually from the annals of neurology, there was a corporate lawyer, who unfortunately had a small prefrontal brain tumour, it was discovered early, operated successfully, after the surgery though it was a very puzzling picture, because he was absolutely as smart as he had been before, a very high IQ, no problem with attention or memory, but he couldn’t do his job anymore, he couldn’t do any job, in fact he ended up out of work, his wife left him, he lost his home, he’s living in his brother spare bedroom and in despair he went to see a famous neurologist named Antonio Damasio. Damasio specialized in the circuitry between the prefrontal area which is where we consciously pay attention to what matters now, where we make decisions, where we learn and the emotional centers in the midbrain, particularly the amygdala, which is our radar for danger, it triggers our strong emotions. They had cut the connection between the prefrontal area and emotional centers and Damasio at first was puzzled, he realized that this fellow on every neurological test was perfectly fine but something was wrong, then he got a clue, he asked the lawyer when should we have our next appointment and he realized the lawyer could give him the rational pros and cons of every hour for the next two weeks, but he didn’t know which is best. And Damasio says when we’re making a decision any decision, when to have the next appointment, should I leave my job for another one, what strategy should we follow, going into the future, should I marry this fellow compared to all the other fellows, those are decisions that require we draw on our entire life experience and the circuitry that collects that life experience is very base brain, it’s very ancient in the brain, and it has no direct connection to the part of the brain that thinks in words, it has very rich connectivity to the gastro- intestinal tract, to the gut, so we get a gut feeling, feels right, doesn’t feel right. Damasio calls them somatic markers, it’s a language of the body and the ability to tune into this is extremely important because this is valuable data too - they did a study of Californian entrepreneurs and asked them “how do you make your decisions?”, these are people who built a business from nothing to hundreds of millions or billions of dollars, and they more or less said the same strategy “I am a voracious gatherer of information, I want to see the numbers, but if it doesn’t feel right, I won’t go ahead with the deal”. They’re tuning into the gut feeling. I know someone, I grew up in farm region of California, the Central Valley and my high school had a rival high school in the next town and I met someone who went to the other high school, he was not a good student, he almost failed, came close to not graduating high school, he went to a two-year college, a community college, found his way into film, which he loved and got into a film school, in film school his student project caught the eye of a director, who asked him to become an assistant and he did so well at that the director arranged for him to direct his own film, someone else’s script, he did so well at that they let him direct a script that he had written and that film did surprisingly well, so the studio that financed that film said if you want to do another one, we will back you. And he, however, hated the way the studio edited the film, he felt he was a creative artist and they had butchered his art. He said I am gonna do the film on my own, I’m gonna finance it myself, everyone in the film business that he knew said this is a huge mistake, you shouldn’t do this, but he went ahead, then he ran out of money, had to go to eleven banks before he could get a loan, he managed to finish the film, you may have seen

As currently understood in neuroscience, emotions are singularly pivotal. Neurologists Hanna and Antonio Damasio, for example, demonstrated in their studies of neurological damage that the emotions are essential elements in reasoning and decision-making. People who lose the ability to feel specific emotions as a result of strokes, head injuries, or tumors also lose the ability to make certain kinds of rational decisions. Thus reason or rationality is not the categorical opposite of emotion or feeling; reason depends on emotion for its functioning.

Over a 10- or 20- or 30- year investment horizon, Mr. Market’s daily dipsy-doodles simply do not matter. In any case, for anyone who will be investing for years to come, falling stock prices are good news, not bad, since they enable you to buy more for less money. The longer and further stocks fall, and the more steadily you keep buying as they drop, the more money you will make in the end—if you remain steadfast until the end. Instead of fearing a bear market, you should embrace it. The intelligent investor should be perfectly comfortable owning a stock or mutual fund even if the stock market stopped supplying daily prices for the next 10 years.11 Paradoxically, “you will be much more in control,” explains neuroscientist Antonio Damasio, “if you realize how much you are not in control.” By acknowledging your biological tendency to buy high and sell low, you can admit the need to dollar-cost average, rebalance, and sign an investment contract. By putting much of your portfolio on permanent autopilot, you can fight the prediction addiction, focus on your long-term financial goals, and tune out Mr. Market’s mood s

The highly regarded neurologist Antonio Damasio, author of Descartes’ Error and The Feeling of What Happens, discovered that emotions literally have an anatomical mapping in the brain necessary for survival.4 That is to say the emotion of fear has a very specific neural circuitry etched in the brain corresponding to specific physical sensations from various parts of the body.

In Descartes’ Error: Emotion, Reason, and the Human Brain,2 neuroscientist Antonio Damasio explained a groundbreaking discovery he made. Studying people who had damage in the part of the brain where emotions are generated, he found that they all had something peculiar in common: They couldn’t make decisions. They could describe what they should do in logical terms, but they found it impossible to make even the simplest choice. In other words, while we may use logic to reason ourselves toward a decision, the actual decision making is governed by emotion.

Neuroscientist Antonio Damasio describes emotions as the "continuous musical line of our minds, the unstoppable humming." This basso continuo thrums along while doctors make a steady stream of conscious medical decisions.

In using the notion of self, I am in no way suggesting that all the contents of our minds are inspected by a single central knower and owner, and even less that such an entity would reside in a single brain place. I am saying, though, that our experiences tend to have a consistent perspective, as if there were indeed an owner and knower for most, though not all, contents. I imagine this perspective to be rooted in a relatively stable, endlessly repeated biological state. The source of the stability is the predominantly invariant structure and operation of the organism, and the slowly evolving elements of autobiographical data.

Our feelings and emotions tell us whether to hold steady in our current state or to make a change. They help us decide the best course of action. Neurologists have discovered that when emotions and feelings are impaired, we actually lose the ability to make decisions. We have no signal of what to pursue and what to avoid. As the neuroscientist Antonio Damasio explains, “It is emotion that allows you to mark things as good, bad, or indifferent.

Desire is the difference between where you are now and where you want to be in the future. Even the tiniest action is tinged with the motivation to feel differently than you do in the moment. When you binge-eat or light up or browse social media, what you really want is not a potato chip or a cigarette or a bunch of likes. What you really want is to feel different. Our feelings and emotions tell us whether to hold steady in our current state or to make a change. They help us decide the best course of action. Neurologists have discovered that when emotions and feelings are impaired, we actually lose the ability to make decisions. We have no signal of what to pursue and what to avoid. As the neuroscientist Antonio Damasio explains, “It is emotion that allows you to mark things as good, bad, or indifferent.” To summarize,

Such interoceptive prodding was visible during a gambling game that formed the basis of an experiment led by neuroscientist Antonio Damasio, a professor at the University of Southern California. In the game, presented on a computer screen, players were given a starting purse of two thousand “dollars” and were shown four decks of digital cards. Their task, they were told, was to turn the cards in the decks face-up, choosing which decks to draw from such that they would lose the least amount of money and win the most. As they started clicking to turn over cards, players began encountering rewards—bonuses of $50 here, $100 there—and also penalties, in which small or large amounts of money were taken away. What the experimenters had arranged, but the players were not told, was that decks A and B were “bad”—they held lots of large penalties in store—and decks C and D were “good,” bestowing more rewards than penalties over time.

Em larga medida, o pensamento é feito de imagens.

Antonio Damasio, a professor of neuroscience, psychology, and philosophy at the University of Southern California, argues that this creation of narratives is one of the greatest powers of consciousness. We cannot, he argues, construct narratives outside of consciousness. And without the capacity to construct them, we wouldn’t be able to recall the past, imagine the future, or plan ahead—abilities that make us human.

Phineas Gage's case is not the only important historical source in the effort to understand the neural basis of reasoning and decision making...[to understand the effect of] prefrontal damage. ... The Hebb-Penfield and Ackerly-Benton shared a number of personality traits...They are bereft of a theory of their own mind and of the mind of those with whom they interact

Phineas Gage's case is not the only important historical source in the effort to understand the neural basis of reasoning and decision making;

Phineas Gage's case is not the only important historical source in the effort to understand the neural basis of reasoning and decision making...[to understand the effect of] prefrontal damage. ... The Hebb-Penfield and Ackerly-Benton shared a number of personality traits...One way of describing their predicament is by saying that they never construct an appropriate theory about their persons.

It is also true that the separate brain units, by virtue of where they are placed in a system, contribute different components to the system's operation and are thus not interchangeable.

The work of neuroscientist Antonio Damasio offers insight into the origins of this guilt. Damasio describes two levels of experiencing pain. The first is a physical response to a painful stimulus. The second, a far more complex reaction, is an emotion associated with pain. This is an internal representation of the physical.

Antonio Damasio reported on patients who suffered damage to the ventromedial frontal cortices of the brain. This damage leaves intelligence, memory, and capacity for logic intact but impairs the ability to feel. Through various experiments, it was surmised that the lack of emotion in the decision-making process destroyed the ability to make rational decisions.3 Indeed, these people became socially dysfunctional. Damasio concluded that emotion is an integral component of making reasonable decisions.

The varied players—objects and events, currently present or recalled from memory—do not pluck the strings of any violins or cellos and do not press the keys of countless pianos, but the metaphor captures the situation. Objects and eventsdo “play,” in the sense that they, as distinct entities within the organism’s mind, can act on certain neural structures of the organism, “affect” their state, and change those other structures for a passing moment. Over the “playing time,” their actions result in a certain kind of music, the music of our thoughts and feelings and of the meanings that emerge from the inner narratives they help construct. The result may be subtle or not so. Sometimes it amounts to an operatic performance. You can attend it passively, or you can intervene, modify the score to a greater or smaller extent, and produce unpredicted results.