Abnormality Related Quotes

The real hopeless victims of mental illness are to be found among those who appear to be most normal. "Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does." They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted.

If we could begin to see much illness itself not as a cruel twist of fate or some nefarious mystery but rather as an expected and therefore normal consequence of abnormal, unnatural circumstances, it would have revolutionary implications for how we approach everything health related.

Relate comic things in pompous fashion. Irregularity, in other words the unexpected, the surprising, the astonishing, are essential to and characteristic of beauty. Two fundamental literary qualities: supernaturalism and irony. The blend of the grotesque and the tragic are attractive to the mind, as is discord to blasé ears. Imagine a canvas for a lyrical, magical farce, for a pantomime, and translate it into a serious novel. Drown the whole thing in an abnormal, dreamy atmosphere, in the atmosphere of great days … the region of pure poetry.

Equality of condition, though it is certainly a basic requirement for justice, is nevertheless among the greatest and most uncertain ventures of modern mankind. The more equal conditions are, the less explanation there is for the differences that actually exist between people; and thus all the more unequal do individuals and groups become. This perplexing consequence came fully to light as soon as equality was no longer seen in terms of an omnipotent being like God or an unavoidable common destiny like death. Whenever equality becomes a mundane fact in itself, without any gauge by which it may be measured or explained, then there is one chance in a hundred that it will be recognized simply as a working principle of a political organization in which otherwise unequal people have equal rights; there are ninety-nine chances that it will be mistaken for an innate quality of every individual, who is “normal” if he is like everybody else and “abnormal” if he happens to be different. This perversion of equality from a political into a social concept is all the more dangerous when a society leaves but little space for special groups and individuals, for then their differences become all the more conspicuous.

If I ever conceive any original idea, it will be because I have been abnormally prone to confuse ideas ... and I have thus found remote analogies and relations which others have not considered! Others rarely make these confusions, and proceed by precise analysis.

The really hopeless victims of mental illness are to be found among those who appear to be most normal. “Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does.” They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted, still cherish “the illusion of individuality,” but in fact they have been to a great extent deindividualized. Their conformity is developing into something like uniformity. But “uniformity and freedom are incompatible. Uniformity and mental health are incompatible too. . . . Man is not made to be an automaton, and if he becomes one, the basis for mental health is destroyed.

For, as I have suggested, disruption of the unity of the self is not limited to the cases that come to physicians and institutions for treatment. They accompany every disturbance of normal relations of husband and wife, parent and child, group and group, class and class, nation and nation. Emotional responses are so total as compared with the partial nature of intellectual responses, of ideas and abstract conceptions, that their consequences are more pervasive and enduring. I can, accordingly, think of nothing of greater practical importance than the psychic effects of human relationships, normal and abnormal, should be the object of continues study, including among the consequences the indirect somatic effects.” – The unity of the human being

Our "increasing mental sickness" may find expres­sion in neurotic symptoms. These symptoms are con­spicuous and extremely distressing. But "let us beware," says Dr. Fromm, "of defining mental hygiene as the prevention of symptoms. Symptoms as such are not our enemy, but our friend; where there are symp­toms there is conflict, and conflict always indicates that the forces of life which strive for integration and happiness are still fighting." The really hopeless victims of mental illness are to be found among those who appear to be most normal. "Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been si­lenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does." They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their per­fect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted, still cherish "the illusion of indi­viduality," but in fact they have been to a great extent deindividualized. Their conformity is developing into something like uniformity. But "uniformity and free­dom are incompatible. Uniformity and mental health are incompatible too. . . . Man is not made to be an automaton, and if he becomes one, the basis for mental health is destroyed.

Stress can be bad for you. We no longer die of smallpox or the plague and instead die of stress-related diseases of lifestyle, like heart disease or diabetes, where damage slowly accumulates over time. It is understood how stress can cause or worsen disease or make you more vulnerable to other risk factors. Much of this is even understood on the molecular level. Stress can even cause your immune system to abnormally target hair follicles, causing your hair to turn gray.

Our “increasing mental sickness” may find expression in neurotic symptoms. These symptoms are conspicuous and extremely distressing. But “let us beware,” says Dr. Fromm, “of defining mental hygiene as the prevention of symptoms. Symptoms as such are not our enemy, but our friend; where there are symptoms there is conflict, and conflict always indicates that the forces of life which strive for integration and happiness are still fighting.” The really hopeless victims of mental illness are to be found among those who appear to be most normal. “Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does.” They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted, still cherish “the illusion of individuality,” but in fact they have been to a great extent deindividualized. Their conformity is developing into something like uniformity. But “uniformity and freedom are incompatible. Uniformity and mental health are incompatible too. . . . Man is not made to be an automaton, and if he becomes one, the basis for mental health is destroyed.

Did you ever read that story about the man who traveled to the future and found everyone there insane? Everyone. But since they were all insane they didn't know they were all insane. They all acted alike and so they thought themselves normal. And since our hero was the only sane one among them, he was abnormal; therefore, he was the insane one. To them, at least. Yes, Mr. Douglas, insanity is relative. It depends on who has who locked in what cage.

Illness in this society, physical or mental, they are not abnormalities. They are normal responses to an abnormal culture. This culture is abnormal when it comes to real human needs. And.. it is in the nature of the system to be abnormal, because if we had a society geared to meet human needs.. would we be destroying the Earth through climate change? Would we be putting extra burden on certain minority people? Would we be selling people a lot of goods that they don't need, and, in fact, are harmful for them? Would there be mass industries based on manufacturing, designing and mass-marketing toxic food to people? So we do all that for the sake of profit. That's insanity. It is not insanity from the point of view of profit, but it is insanity from the point of view of human need. And so, in so many ways this culture denies and even runs against counter to human needs. When you mentioned trauma.. given how important trauma is in human life and what an impact it has.. why have we ignored it for so long? Because that denial of reality is built in into this system. It keeps the system alive. So it is not a mistake, it is a design issue. Not that anybody consciously designed it, but that's just how the system survives. Now.. the average medical student to THIS DAY (I say the average.. there are exceptions) still doesn't get a single lecture on trauma in 4 years of medical school. They should have a whole course on it, Because I can tell you that trauma is related to addiction, all kinds of mental illness and most physical health conditions as well. And there is a whole lot of science behind that, but they don't study that science. Now that reflects this society's denial of trauma, the medical system simply reflects the needs of the larger society, I should say, the dominant needs of the larger society.

Individuals are labeled “different,” “geeky,” “abnormal,” or even “Aspergian” or “autistic” at a young age. Among other things, these labels suggest that the people around them—their family, friends, teachers, and counselors—can’t relate to their actions and expressions.

After this Daisy was never at home, and Winterbourne ceased to meet her at the houses of their common acquaintances, because, as he perceived, these shrewd people had quite made up their minds that she was going too far. They ceased to invite her, and they intimated that they desired to express observant Europeans the great truth that, though Miss Daisy Miller was a young American lady, her behaviour was not representative - was regarded by her compatriots as abnormal. Winterbourne wondered how she felt about all the cold shoulders that were turned towards her, and sometimes it annoyed him to suspect that she did not feel at all. He said to himself that she was too light and childish, too uncultivated and unreasoning, too provincial, to have reflected upon her ostracism or even to have perceived it. Then at other moments he believed that she carried about in her elegant and irresponsible little organism a defiant, passionate, perfectly observant consciousness of the impression she produced. He asked himself whether Daisy's defiance came from the consciousness of innocence or from her being, essentially, a young person of the reckless class. It must be admitted that holding oneself to a belief in Daisy's "innocence" came to see Winterbourne more and more a matter of fine-spun gallantry. As I have already had occasion to relate, he was angry at finding himself reduced to chopping logic about this young lady; he was vexed at his want of instinctive certitude as to how far her eccentricities were generic, national, and how far they were personal. From either view of them he had somehow missed her, and now it was too late.

we could begin to see much illness itself not as a cruel twist of fate or some nefarious mystery but rather as an expected and therefore normal consequence of abnormal, unnatural circumstances, it would have revolutionary implications for how we approach everything health related.

Whatever the evolutionary precursors of drug use are, a permanently “drug-free” human culture has yet to be discovered. Like music, language, art, and tool use, the pursuit of altered states of consciousness is a human universal. With access to few alternatives, Siberian shamans imbibe reindeer and human urine to maximize the psychedelic yield of Amanita muscaria mushrooms (the metabolite that is excreted may be stronger than the substance initially ingested); on nearly the opposite side of the world, New Zealanders party with untested “research chemicals” synthesized by Chinese chemists. Drug use spans time and culture. It is a rare human who has never taken a drug to alter her mood; statistically, it is non-users who are abnormal. Indeed, today, around two thirds of Americans over 12 have had at least one drink in the last year, and 1 in 5 are current smokers. (In the 1940s and ’50s, a whopping 67% of men smoked.) Among people ages 21 to 25, 60% have taken an illegal drug at least once—overwhelmingly marijuana—and 20% have taken one in the past month. Moreover, around half of us could suffer from physical withdrawal symptoms if denied our daily coffee. While Americans are relatively prodigious drug users—topping the charts in the use of many substances—we are far from alone in our psychoactive predilections.

The starting point of Darwin's theory of evolution is precisely the existence of those differences between individual members of a race or species which morphologists for the most part rightly neglect. The first condition necessary, in order that any process of Natural Selection may begin among a race, or species, is the existence of differences among its members; and the first step in an enquiry into the possible effect of a selective process upon any character of a race must be an estimate of the frequency with which individuals, exhibiting any given degree of abnormality with respect to that, character, occur. The unit, with which such an enquiry must deal, is not an individual but a race, or a statistically representative sample of a race; and the result must take the form of a numerical statement, showing the relative frequency with which the various kinds of individuals composing the race occur.

Collectively this work suggests that the prefrontal cortex and the amygdala are reciprocally related. That is, in order for the amygdala to respond to fear reactions, the prefrontal region has to be shut down. By the same logic, when the prefrontal region is active, the amygdala would be inhibited, making it harder to express fear. Pathological fear, then, may occur when the amygdala is unchecked by the prefrontal cortex, and treatment of pathological fear may require that the patient learn to increase activity in the prefrontal region so that the amygdala is less free to express fear. Clearly, decision-making ability in emotional situations is impaired in humans with damage to the medial and ventral prefrontal cortex, and abnormalities there also may predispose people to develop fear and anxiety disorders. These abnormalities could be due to genetic or epigenetic organization of prefrontal synapses or to experiences that subtly alter prefrontal synaptic connections. Indeed, the behavior of animals with abmormalities of the medial prefrontal cortex is reminiscent of humans with anxiety disorders: they develop fear reactions that are difficult to regulate. Although objective information about the world may indicate that a situation is not dangerous, because they cannot properly regulate fear circuits, they experience fear and anxiety in these safe situations.

How have individuals been affected by the technological advances of recent years? Here is the answer to this question given by a philosopher-psychiatrist, Dr. Erich Fromm: Our contemporary Western society, in spite of its material, intellectual and political progress, is increasingly less conducive to mental health, and tends to undermine the inner security, happiness, reason and the capacity for love in the individual; it tends to turn him into an automaton who pays for his human failure with increasing mental sickness, and with despair hidden under a frantic drive for work and so-called pleasure. Our "increasing mental sickness" may find expression in neurotic symptoms. These symptoms are conspicuous and extremely distressing. But "let us beware," says Dr. Fromm, "of defining mental hygiene as the prevention of symptoms. Symptoms as such are not our enemy, but our friend; where there are symptoms there is conflict, and conflict always indicates that the forces of life which strive for integration and happiness are still fighting." The really hopeless victims of mental illness are to be found among those who appear to be most normal. "Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does." They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted, still cherish "the illusion of individuality," but in fact they have been to a great extent deindividualized. Their conformity is developing into something like uniformity. But "uniformity and freedom are incompatible. Uniformity and mental health are incompatible too. ... Man is not made to be an automaton, and if he becomes one, the basis for mental health is destroyed.

Unfortunately, most researchers studying gating dynamics in children are, as with “schizophrenia,” focused on “normal” versus “abnormal” gating. And all children are expected to fit into the defined “normal” range of behavior. Sensory gating dynamics outside that culturally determined “norm” are defined as abnormal and researchers note that Individuals with these characteristics have been classified as having sensory processing deficits (SPD). Such behaviors disrupt an individual’s ability to achieve and maintain an optimal range of performance necessary to adapt to challenges in life. The manifestations of SPD may include distraction, impulsiveness, abnormal activity level, disorganization, anxiety, and emotional lability that produce deficient social participation, insufficient self-regulation and inadequate perceived competence.1 Those terms, if you look at them more closely, are exterior, “authority” generated terms; they relate directly to the paradigm in place in those authorities. They really don’t have much to say about the interior experience of the children so labeled.

The absence of the rights of woman does not consist in the fact that she has not the right to vote, or the right to sit on the bench, but in the fact that in her affectional relations she is not the equal of man, she has not the right to abstain, to choose instead of being chosen. You say that that would be abnormal. Very well! But then do not let man enjoy these rights, while his companion is deprived of them, and finds herself obliged to make use of the coquetry by which she governs, so that the result is that man chooses ‘formally,’ whereas really it is woman who chooses. As soon as she is in possession of her means, she abuses them, and acquires a terrible supremacy.

I think it was Lessing who once said, “There are things which must cause you to lose your reason or you have none to lose.” An abnormal reaction to an abnormal situation is normal behavior. Even we psychiatrists expect the reactions of a man to an abnormal situation, such as being committed to an asylum, to be abnormal in proportion to the degree of his normality. The reaction of a man to his admission to a concentration camp also represents an abnormal state of mind, but judged objectively it is a normal and, as will be shown later, typical reaction to the given circumstances. These reactions, as I have described them, began to change in a few days. The prisoner passed from the first to the second phase; the phase of relative apathy, in which he achieved a kind of emotional death. Apart

How have individuals been affected by the technological advances of recent years? Here is the answer to this question given by a philosopher-psychiatrist, Dr Erich Fromm: ‘Our contemporary Western society, in spite of its material, intellectual and political progress, is increasingly less conducive to mental health, and tends to undermine the inner security, happiness, reason and the capacity for love in the individual; it tends to turn him into an automaton who pays for his human failure with increasing mental sickness, and with despair hidden under a frantic drive for work and so-called pleasure.’ Our ‘increasing mental sickness’ may find expression in neurotic symptoms. These symptoms are conspicuous and extremely distressing. But ‘let us beware’, says Dr Fromm, ‘of defining mental hygiene as the prevention of symptoms. Symptoms as such are not our enemy, but our friend; where there are symptoms there is conflict, and conflict always indicates that the forces of life which strive for integration and happiness are still fighting.’ The really hopeless victims of mental illness are to be found among those who appear to be most normal. ‘Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does.’ They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness.

Inanna was the only Mesopotamian deity whose character so prominently included contradictions... In her actions, Inanna exhibits both benevolent light and threatening dark. Her violence and destructiveness go beyond the boundaries of tolerable human behavior. She carries light and dark to their extremes. Inanna's immense popularity in antiquity must be related in part to the fact that she could reflect not only the best in human nature, but she could also exhibit what is abhorrent, unpleasant, dirty, sinful, terrifying, abnormal, perverse, obsessive, murderous, mad and violent. Inanna is a mirror of what Jung called ¨the abysmal contracictions of human nature.¨ She shows us our oppositions in sharp relief. She is a divine manifestation of the ultimate conjunction of opposites, displaying for humankind its contradictory nature.

Most people now have the ‘LDL-C is bad and HDL-C is good’ concept down pat. But there is more to the story. It is well established that not all LDL particles are created equal. Moreover, certain types of LDL have been shown to correlate with abnormal lipid profiles and promote atherosclerosis. As noted previously, the larger more buoyant LDL particles are less harmful than smaller ones. Small LDL particles reside in the circulation longer, have greater susceptibility to oxidative damage by free radicals, and more easily penetrate the arterial wall, contributing to atherosclerosis. No matter what your total LDL-C concentration, if you have relatively more small particles (referred to as Pattern B) it puts you at a several-fold higher risk for heart disease compared to people with larger LDL particles (Pattern A)[49]. And once again, this is independent of your LDL-C concentration.

What happened to factual, down-the-middle reporting? That’s hard to even define anymore, as the line between fact and fiction, between truth and lies, gets murkier every day. We can’t survive without a free press, dedicated to preserving that fine line and secure enough to follow the facts where they lead. But the current environment imposes serious pressures on our journalists, at least those who cover politics, to do just the reverse—to exercise their own power and to, in the words of one wise columnist, “abnormalize” all politicians, even honest, able ones, often because of relatively insignificant issues. Scholars call this false equivalency. It means that when you find a mountain to expose in one person or party, you have to pick a molehill on the other side and make it into a mountain to avoid being accused of bias. The built-up molehills also have large benefits: increased coverage on the evening news, millions of retweets, and more talk-show fodder. When the mountains and molehills all look the same, campaigns and governments devote too little time and energy debating the issues that matter most to our people. Even when we try to do that, we’re often drowned out by the passion of the day.

Nonconformity is an affront to those in the mainstream. Our impulse is to dismiss this lifestyle, create reasons why it can’t work, why it doesn’t even warrant consideration. Why not? Living outdoors is cheap and can be afforded by a half year of marginal employment. They can’t buy things that most of us have, but what they lose in possessions, they gain in freedom. In Somerset Maugham’s The Razor’s Edge, lead character Larry returns from the First World War and declares that he would like to “loaf.”23 The term “loafing” inadequately describes the life he would spend traveling, studying, searching for meaning, and even laboring. Larry meets with the disapproval of peers and would-be mentors: “Common sense assured…that if you wanted to get on in this world, you must accept its conventions, and not to do what everybody else did clearly pointed to instability.” Larry had an inheritance that enabled him to live modestly and pursue his dreams. Larry’s acquaintances didn’t fear the consequences of his failure; they feared his failure to conform. I’m no maverick. Upon leaving college I dove into the workforce, eager to have my own stuff and a job to pay for it. Parents approved, bosses gave raises, and my friends could relate. The approval, the comforts, the commitments wound themselves around me like invisible threads. When my life stayed the course, I wouldn’t even feel them binding. Then I would waiver enough to sense the growing entrapment, the taming of my life in which I had been complicit. Working a nine-to-five job took more energy than I had expected, leaving less time to pursue diverse interests. I grew to detest the statement “I am a…” with the sentence completed by an occupational title. Self-help books emphasize “defining priorities” and “staying focused,” euphemisms for specialization and stifling spontaneity. Our vision becomes so narrow that risk is trying a new brand of cereal, and adventure is watching a new sitcom. Over time I have elevated my opinion of nonconformity nearly to the level of an obligation. We should have a bias toward doing activities that we don’t normally do to keep loose the moorings of society. Hiking the AT is “pointless.” What life is not “pointless”? Is it not pointless to work paycheck to paycheck just to conform? Hiking the AT before joining the workforce was an opportunity not taken. Doing it in retirement would be sensible; doing it at this time in my life is abnormal, and therein lay the appeal. I want to make my life less ordinary.

We are all poor; but there is a difference between what Mrs. Spark intends by speaking of 'slender means', and what Stevens called our poverty or Sartre our need, besoin. The poet finds his brief, fortuitous concords, it is true: not merely 'what will suffice,' but 'the freshness of transformation,' the 'reality of decreation,' the 'gaiety of language.' The novelist accepts need, the difficulty of relating one's fictions to what one knows about the nature of reality, as his donnée. It is because no one has said more about this situation, or given such an idea of its complexity, that I want to devote most of this talk to Sartre and the most relevant of his novels, La Nausée. As things go now it isn't of course very modern; Robbe-Grillet treats it with amused reverence as a valuable antique. But it will still serve for my purposes. This book is doubtless very well known to you; I can't undertake to tell you much about it, especially as it has often been regarded as standing in an unusually close relation to a body of philosophy which I am incompetent to expound. Perhaps you will be charitable if I explain that I shall be using it and other works of Sartre merely as examples. What I have to do is simply to show that La Nausée represents, in the work of one extremely important and representative figure, a kind of crisis in the relation between fiction and reality, the tension or dissonance between paradigmatic form and contingent reality. That the mood of Sartre has sometimes been appropriate to the modern demythologized apocalypse is something I shall take for granted; his is a philosophy of crisis, but his world has no beginning and no end. The absurd dishonesty of all prefabricated patterns is cardinal to his beliefs; to cover reality over with eidetic images--illusions persisting from past acts of perception, as some abnormal children 'see' the page or object that is no longer before them --to do this is to sink into mauvaise foi. This expression covers all comfortable denials of the undeniable--freedom --by myths of necessity, nature, or things as they are. Are all the paradigms of fiction eidetic? Is the unavoidable, insidious, comfortable enemy of all novelists mauvaise foi? Sartre has recently, in his first instalment of autobiography, talked with extraordinary vivacity about the roleplaying of his youth, of the falsities imposed upon him by the fictive power of words. At the beginning of the Great War he began a novel about a French private who captured the Kaiser, defeated him in single combat, and so ended the war and recovered Alsace. But everything went wrong. The Kaiser, hissed by the poilus, no match for the superbly fit Private Perrin, spat upon and insulted, became 'somehow heroic.' Worse still, the peace, which should instantly have followed in the real world if this fiction had a genuine correspondence with reality, failed to occur. 'I very nearly renounced literature,' says Sartre. Roquentin, in a subtler but basically similar situation, has the same reaction. Later Sartre would find again that the hero, however assiduously you use the pitchfork, will recur, and that gaps, less gross perhaps, between fiction and reality will open in the most close-knit pattern of words. Again, the young Sartre would sometimes, when most identified with his friends at the lycée, feel himself to be 'freed at last from the sin of existing'--this is also an expression of Roquentin's, but Roquentin says it feels like being a character in a novel. How can novels, by telling lies, convert existence into being? We see Roquentin waver between the horror of contingency and the fiction of aventures. In Les Mots Sartre very engagingly tells us that he was Roquentin, certainly, but that he was Sartre also, 'the elect, the chronicler of hells' to whom the whole novel of which he now speaks so derisively was a sort of aventure, though what was represented within it was 'the unjustified, brackish existence of my fellow-creatures.

Interactions with the world program our physiological and psychological development. Emotional contact is as important as physical contact. The two are quite analogous, as we recognize when we speak of the emotional experience of feeling touched. Our sensory organs and brains provide the interface through which relationships shape our evolution from infancy to adulthood. Social-emotional interactions decisively influence the development of the human brain. From the moment of birth, they regulate the tone, activity and development of the psychoneuroimmunoendocrine (PNI) super-system. Our characteristic modes of handling psychic and physical stress are set in our earliest years. Neuroscientists at Harvard University studied the cortisol levels of orphans who were raised in the dreadfully neglected child-care institutions established in Romania during the Ceausescu regime. In these facilities the caregiver/child ratio was one to twenty. Except for the rudiments of care, the children were seldom physically picked up or touched. They displayed the self-hugging motions and depressed demeanour typical of abandoned young, human or primate. On saliva tests, their cortisol levels were abnormal, indicating that their hypothalamic-pituitary-adrenal axes were already impaired. As we have seen, disruptions of the HPA axis have been noted in autoimmune disease, cancer and other conditions. It is intuitively easy to understand why abuse, trauma or extreme neglect in childhood would have negative consequences. But why do many people develop stress-related illness without having been abused or traumatized? These persons suffer not because something negative was inflicted on them but because something positive was withheld.

Nobody as yet had really acknowledged to himself what the disease connoted. Most people were chiefly aware of what ruffled the normal tenor of their lives or affected their interests. They were worried and irritated—but these are not feelings with which to confront plague. Their first reaction, for instance, was to abuse the authorities. The Prefect’s riposte to criticisms echoed by the press—Could not the regulations be modified and made less stringent?—was somewhat unexpected. Hitherto neither the newspapers nor the Ransdoc Information Bureau had been given any official statistics relating to the epidemic. Now the Prefect supplied them daily to the bureau, with the request that they should be broadcast once a week. In this, too, the reaction of the public was slower than might have been expected. Thus the bare statement that three hundred and two deaths had taken place in the third week of plague failed to strike their imagination. For one thing, all the three hundred and two deaths might not have been due to plague. Also, no one in the town had any idea of the average weekly death-rate in ordinary times. The population of the town was about two hundred thousand. There was no knowing if the present death-rate were really so abnormal. This is, in fact, the kind of statistics that nobody ever troubles much about—notwithstanding that its interest is obvious. The public lacked, in short, standards of comparison. It was only as time passed and the steady rise in the death-rate could not be ignored that public opinion became alive to the truth. For in the fifth week there were three hundred and twenty-one deaths, and three hundred and forty-five in the sixth. These figures, anyhow, spoke for themselves. Yet they were still not sensational enough to prevent our townsfolk, perturbed though they were, from persisting in the idea that what was happening was a sort of accident, disagreeable enough, but certainly of a temporary order. So they went on strolling about the town as usual and sitting at the tables on café terraces. Generally speaking, they did not lack courage, bandied more jokes than lamentations, and made a show of accepting cheerfully unpleasantnesses that obviously could be only passing. In short, they kept up appearances.

How have individuals been affected by the technological advances of recent years? Here is the answer to this question given by a philosopher-psychiatrist, Dr Erich Fromm: ‘Our contemporary Western society, in spite of its material, intellectual and political progress, is increasingly less conducive to mental health, and tends to undermine the inner security, happiness, reason and the capacity for love in the individual; it tends to turn him into an automaton who pays for his human failure with increasing mental sickness, and with despair hidden under a frantic drive for work and so-called pleasure.’ Our ‘increasing mental sickness’ may find expression in neurotic symptoms. These symptoms are conspicuous and extremely distressing. But ‘let us beware’, says Dr Fromm, ‘of defining mental hygiene as the prevention of symptoms. Symptoms as such are not our enemy, but our friend; where there are symptoms there is conflict, and conflict always indicates that the forces of life which strive for integration and happiness are still fighting.’ The really hopeless victims of mental illness are to be found among those who appear to be most normal. ‘Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does.’ They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted, still cherish ‘the illusion of individuality’, but in fact they have been to a great extent de-individualized. Their conformity is developing into something like uniformity. But ‘uniformity and freedom are incompatible. Uniformity and mental health are incompatible too . . . Man is not made to be an automaton, and if he becomes one, the basis for mental health is destroyed.’ In the course of evolution nature has gone to endless trouble to see that every individual is unlike every other individual. We reproduce our kind by bringing the father’s genes into contact with the mother’s. These hereditary factors may be combined in an almost infinite number of ways. Physically and mentally, each one of us is unique. Any culture which, in the interests of efficiency or in the name of some political or religious dogma, seeks to standardize the human individual, commits an outrage against man’s biological nature.

14 One Sabbath, when Jesus went to eat in the house of a prominent Pharisee, he was being carefully watched. 2 There in front of him was a man suffering from abnormal swelling of his body. 3 Jesus asked the Pharisees and experts in the law, “Is it lawful to heal on the Sabbath or not?” 4 But they remained silent. So taking hold of the man, he healed him and sent him on his way. 5 Then he asked them, “If one of you has a child[a] or an ox that falls into a well on the Sabbath day, will you not immediately pull it out?” 6 And they had nothing to say. 7 When he noticed how the guests picked the places of honor at the table, he told them this parable: 8 “When someone invites you to a wedding feast, do not take the place of honor, for a person more distinguished than you may have been invited. 9 If so, the host who invited both of you will come and say to you, ‘Give this person your seat.’ Then, humiliated, you will have to take the least important place. 10 But when you are invited, take the lowest place, so that when your host comes, he will say to you, ‘Friend, move up to a better place.’ Then you will be honored in the presence of all the other guests. 11 For all those who exalt themselves will be humbled, and those who humble themselves will be exalted.” 12 Then Jesus said to his host, “When you give a luncheon or dinner, do not invite your friends, your brothers or sisters, your relatives, or your rich neighbors; if you do, they may invite you back and so you will be repaid. 13 But when you give a banquet, invite the poor, the crippled, the lame, the blind, 14 and you will be blessed. Although they cannot repay you, you will be repaid at the resurrection of the righteous.

The brain’s response to messages from its environment is shaped by its experiences—experiences not only during gestation and infancy, as most neuroscientists were prepared to accept, but by our experiences throughout life. The life we live, in other words, shapes the brain we develop. To Merzenich, the real significance of the findings was what they said about the origins of behavior and mental impairments. “This machine we call the brain is being modified throughout life,” he mused almost twenty years later. “The potential for using this for good had been there for years. But it required a different mindset, one that did not view the brain as a machine with fixed parts and defined capacities, but instead as an organ with the capacity to change throughout life. I tried so hard to explain how this would relate to both normal and abnormal behavior. But there were very few takers. Few people grasped the implications.” For a while, it appeared that the monkeys’ brains were a lot more adaptable than the research community’s.

NAFLD has been associated with cognitive deficits, which increase with the severity of the disease. In mice that are overfed to develop NAFLD, brain changes associated with Alzheimer’s disease begin to emerge, and mice that already had Alzheimer’s-related abnormalities (not a perfect model of human Alzheimer’s, but interesting nonetheless) exhibit exacerbated signs of disease and greater inflammation when fed concentrated fructose.23

Indoctrination,” Michael Simpson replied. “We still base our science on the Theory of Relativity. Not because it is one hundred percent correct, but because it provides us with the most accurate picture of the universe per today. The Nazis considered the Theory of Relativity as a predominantly Jewish theory. The Germans developed Quantum Theory, a theory which in many cases has solutions that contradict our common sense. But the solutions are only illogical because we compare them to what we can observe here in our little corner of the universe. We assume that our world is normal, but it isn’t. Our little world is an abnormality in the universe. With this perspective everything becomes much clearer. A team of scientists, relieved of all historical doctrine, open to the occult and totally devoid of any morals and human worth. Such a team of scientists may have come up with totally new concepts and ways of approaching problems. Maybe they came up with a new theory. An alternative to the Theory of Relativity. A theory that doesn’t have the limitations the Theory of Relativity has.” “I

Only after the concept of knowledge has been based on an ontological relation [*Seinsverhältnis*] can we work out the particular kind of being from which the principle of immanence-to-consciousness (the starting point of Idealism and Critical Realism) mistakenly proceeds as though from a primary insight. This is the being of "being-conscious" [*Bewusst-Seins*]. All being-conscious must first of all be brought under the higher concept of ideal being, or, at all events, that of irreal being. The mental item which presents itself in the experiences of consciousness may be real; being-conscious itself never is. However, the concept of consciousness is derivative in not only this sense. Consciousness also presupposes the concept of knowledge. Nothing is more misleading than to proceed in the opposite direction and define knowledge itself as simply a particular "content of consciousness," as we see if we oppose, to the particular kind of knowing and having-known which we call consciousness, another kind of knowledge which precedes it and includes no form of being-conscious. We will call this knowledge *ecstatic* [*ekstatische*] knowledge. It is found quite clearly in animals, primitive people, children, and, further, in certain pathological and other abnormal and supra-normal states (e.g., in recovering from the effects of a drug). I have said elsewhere that the animal never relates to its environment as to an object but only *lives in it* [*es lebe nur "in sie hinein*"]. Its conduct with respect to the external world depends upon whether the latter satisfies its instinctive drives or denies them satisfaction. The animal experiences the surrounding world as resistances of various types. Hence, it is absolutely necessary to contest the principle (in Descartes, Franz Brentano, *et al*.) that every mental function and act is accompanied by an immediate knowledge of it. An even more highly contestable principle is that a relation to the self is an essential condition of all processes of knowledge. It is difficult to reproduce purely ecstatic knowledge in mature, civilized men, whether in memory, reverie, perception, thought, or empathetic identification with things, animals, or men; nonetheless, there is no doubt that in every perception and presentation of things and events we think that we grasp *the things-themselves*, not mere "images" of them or representatives of some sort. Knowledge first becomes conscious knowledge [*Bewusst-sein*], that is, comes out of its original ecstatic form of simply "having" things, in which there is no knowledge of the having or of that through which and in which it is had, when the act of being thrown back on the self (probably only possible for men) comes into play. This act grows out of conspicuous resistances, clashes, and oppositions―in sum, out of pronounced suffering. It is the *actus re-flexivus* in which knowledge of the knowledge of things is added to the knowledge of things. Furthermore, in this act we come to know the kind of knowledge we have, for example, memory, ideation, and perception, and finally, beyond even these, we come to have a knowledge of the relation of the act performed to the self, to the knower. With respect to any specific relation to the self, this last knowledge, so-called conscious self-knowledge, comes only after knowledge about the act. Kant's principle that an "I think" must be *able* to accompany all a man's thoughts may be correct. That it in fact always accompanies them is nevertheless undoubtedly false. However, the kind of being (indeed, of ideal being) which contents possess when they are reflexively *had* in their givenness in conscious acts―when, therefore, they become reflexive―is the being of being-consciously-known." from_Idealism and Realism_

Empirical logic achieved a signal triumph in the Old Testament, where survivals from the early proto-logical stage are very few and far between. With it man reached a point where his best judgments about his relation to God, his fellow men and the world, were in most respects not appreciably inferior to ours. In fundamental ethical and spiritual matters we have not progressed at all beyond the empirico-logical world of the Old Testament or the unrivalled fusion of proto-logical intuition, 64 [see Coomaraswamy, Review of Religion, 1942, p. 138, paragraph 3] empirico-logical wisdom and logical deduction which we find in the New Testament. In fact a very large section of modern religion, literature and art actually represents a pronounced retrogression when compared with the Old Testament. For example, astrology, spiritism and kindred divagations, which have become religion to tens of millions of Europeans and Americans, are only the outgrowth of proto-logical interpretation of nature, fed by empirico-logical data and covered with a spurious shell of Aristotelian logic and scientific induction. Plastic and graphic art has swung violently away from logical perspective and perceptual accuracy, and has plunged into primordial depths of conceptual drawing and intuitive imagery. While it cannot be denied that this swing from classical art to conceptual and impressionistic art has yielded some valuable results, it is also true that it represents a very extreme retrogression into the proto-logical past. Much of the poetry, drama and fiction which has been written during the past half-century is also a reversion from classical and logical standards of morality and beauty into primitive savagery or pathological abnormality. Some of it has reached such paralogical levels of sophistication that it has lost all power to furnish any standards at all to a generation which has deliberately tried to abandon its entire heritage from the past. All systematic attempts to discredit inherited sexual morality, to substitute dream-states for reflection, and to replace logical writing by jargon, are retreats into the jungle from which man emerged through long and painful millennia of disillusionment. With the same brains and affective reactions as those which our ancestors possessed two thousand years ago, increasing sophistication has not been able to teach us any sounder fundamental principles of life than were known at that time. . . . Unless we can continue along the pathway of personal morality and spiritual growth which was marked out for civilized man by the founders of the Judaeo-Christian tradition, more than two thousand years ago, our superior skill in modifying and even in transforming the material world about us can lead only to repeated disasters, each more terrible than its predecessor. (Archaeology and the Religion of Israel, 5th Ed. New York: Doubleday Anchor, 31-33.)

When Mrs. Kondo spoke to me in 1989, her daughter was forty-five years old and living far away on Hokkaido in northern Japan. The younger woman suffered the classic symptoms of fetal exposure: microcephaly and mental retardation. With her mother’s constant support, she had finished basic schooling, had married, and had borne two children of her own. The children showed no symptoms of abnormality; as in so many other cases, there was no evidence of a genetic effect. But Mrs. Kondo’s daughter cannot function as a normal mother in her state of limited mental capability. So she relates to her children much as a sister, and others bear the responsibility of parenthood.

The night shift workers were unusual characters. They ranged from relatively normal to bizarre. It was widely acknowledged within the group that most personalities were abnormal. It was consistent with the sleep deprivation they were subjected to. The winter nights were really long and the days were too short for sufficient restorative sleeping. I was hallucinating while driving atop Mauna Kea! Inside the telescope control room I could feel a presence and would go looking for the person I thought was in the control room with me. I never found them. The summit is a spiritual place according to the Hawaiians. I most certainly had an invisible friend up there!

In many ways, the treatment of animal homosexuality in the scientific discourse has closely parallelled the discussion of human homosexuality in society at large. Homosexuality in both animals and people has been considered, at various times, to be a pathological condition; a social aberration; an "immoral", "sinful", or "criminal" perversion; an artificial product of confinement or the unavailability of the opposite sex; a reversal or "inversion" of heterosexual "roles"; a "phase" that younger animals go through on the path to heterosexuality; an exceptional but unimportant activity; a useless and puzzling curiosity; and a functional behavior that "stimulates" or "contributes to" heterosexuality. In many other respects, however, the outright hostility to animal homosexuality has transcended all historical trends. One need only look at the litany of derogatory terms, which have remained essentially constant from the late 1800s to the present day, used to describe this behavior: words such as strange, bizarre, perverse, aberrant, deviant, abnormal, anomalous, and unnatural have all been used routinely in "objective" scientific descriptions of the phenomenon and continue to be used (one of the most recent examples is from 1997). In addition, heterosexual behavior is consistently defined in numerous scientific accounts as "normal" in contrast to homosexual activity... In a direct carryover from attitudes toward human homosexuality, same-sex activity is routinely described as being "forced" on other animals when there is no evidence that it is, and a whole range of "distressful" emotions are projected onto the individual who experiences such "unwanted advances"... In other cases, zoologists have problematized homosexual activity or imputed an inherent inadequacy, instability, or incompetence to same-sex relations, when the supporting evidence for this is scanty or questionable at best and nonexistent at worst.

Many studies have found that people suffering from depression show unique symptoms in their bodies.9 These symptoms include too low amounts of various brain chemicals (norepinephrine, serotonin, and dopamine), a too high amount of a stress hormone (cortisol), and disturbance of deep dream-related (REM) sleep. Furthermore, new technologies allowing researchers to image the brain have revealed that severely depressed patients have abnormalities in the prefrontal cortex (the region of the brain responsible for thinking and managing emotions) as well as in the limbic regions (i.e., areas involved in sleep, eating, sex, motivation, memory, and responses to stress), including the mysterious-sounding Area 25.10 In sum, there is now a great deal of evidence that depression is partly rooted in those parts of our physical bodies over which we have minimal control.

Some of the things you will write in your journal include: »A list of all expenses, which will be important for tax time should you decide to sell honey or bee-related products. »The health of your hive when you inspect it. »Anything that concerns you or things that seem abnormal. »When you did your last inspection. »If you treat for pests, what you used and how much you applied.

The political left’s cultural revolution on the sexual-gender-family front is ubiquitous, as is its intolerance of any dissenters. We see it in the culture of fear and intimidation by the self-prided forces of “diversity” and “tolerance” who viciously seek to denounce, dehumanize, demonize, and destroy anyone who disagrees with their brazen newfound conceptions of marriage and family, even as their inventions are at odds with the prevailing position of 99.99 percent-plus of human beings who have bestrode the earth since the dawn of humanity. Instead, traditional Christians are the ones portrayed as the outliers, as abnormal, as extremists, as bigots, as “haters.” That is a fundamental transformation of a culture and a nation. That is evidence of a true revolution by the heirs of Marx and other radicals. “The Most Radical Rupture in Traditional Relations” To “fundamentally transform.” Here was, in essence, an inherently Marxist goal declared to a sea of oblivious Americans, whether Barack Obama explicitly or fully understood or meant it himself. It is highly doubtful that Obama had Marx (or a Marcuse or Millett or Reich) on the mind at that moment.665 Obama was merely riding a wave that began as a ripple over a century or so ago. And typically, most of those surfing or floating along have little notion who or what helped give the initial push. Nonetheless, the goal of Karl Marx and the Marxist project from the outset was one of fundamental transformation, permanent revolution, and unrestrained criticism of everything—nothing less than “the ruthless criticism of all that exists.”666 Marx’s ideas were so radical, and so (as Marx openly conceded) “contrary to the nature of things,” that they inevitably lead to totalitarianism; that is because they are totalitarian in the strictest sense, as they seek to transform human nature and the foundational order. We have seen passages from Marx to that effect throughout this book. Here is a short summary: Marx in the Manifesto said that communism represents “the most radical rupture in traditional relations.” Marx in the Manifesto acknowledged that communism seeks to “abolish the present state of things.” Marx in the Manifesto stated that “they [the Communists] openly declare that their ends can be attained only by the forcible overthrow of all existing social conditions.” Marx in the close of the Manifesto: “Communists everywhere support every revolutionary movement against the existing social and political order of things.” Marx in a letter to Arnold Ruge called for the “ruthless criticism of all that exists.” Marx had a favorite quote from Goethe’s Faust, “Everything that exists deserves to perish.” • Marx in his essay declaring religion “the opium of the people” said that “the criticism of religion is the beginning of all criticism.” (Recall that in that essay he used the word “criticism” twenty-nine times.) Beyond

The real hopeless victims of mental illness are to be found among those who appear to be the most normal. Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does. They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted.

comfortable. It doesn’t matter if she reciprocates and decides to be completely open with you. If she does want to, you can welcome her honesty. But the main point of this exercise is for you to be honest with her. Remember, being honest with her means taking responsibility for your feelings, rather than shaming and blaming. You need to do the following for at least one week: In the evening or near the end of every day, sit down with your wife or loved one. Be completely honest with her about any kind of abnormal thinking you had during that day. You might want to go through your day and relate anything you were ashamed of thinking. You don’t have to restrict yourself to thoughts about sex, because sex addiction is not just about sex. It’s about self-esteem and how you view yourself and your stories. Again, if your wife reciprocates, it could bring you closer. But don’t pressure her. If she does reciprocate, she also needs to avoid shaming and blaming. However, she doesn’t have to say a word. This exercise is about you being honest with people who are close to you. If you are open and honest, your wife is more likely to respond with loving-kindness. If you are vulnerable, you invite vulnerability.

Bauer considered the fat tissue in obesity akin to malignant tumors. Both have their own agendas, he explained. Tumors are driven to grow and spread and will do so with little relation to how much the person who has that tumor might be eating or exercising. In those who are predisposed to grow obese, fat tissue is driven to grow, to expand with fat, and it will accomplish this goal, just as the tumor does, with little concern about what the rest of the body might be doing. “The abnormal lipophilic tissue seizes on foodstuffs, even in the case of undernutrition,” Bauer wrote in 1929. “It maintains its stock, and may increase it independent of the requirements of the organism. A sort of anarchy exists; the adipose tissue lives for itself and does not fit into the precisely regulated management of the whole organism.

And indeed, many trauma-related health problems are dismissed, missed, and misunderstood. But once you understand more about neuroscience, and how our senses and brain translate experience into “biological” activity, the artificial distinctions disappear. If you understand the neurobiology of trauma, you know that a physical “abnormality” is causing the abdominal pain seen with sensitized dissociation. You begin to see that a person’s “worldview” can change their immune system, and that a positive conversation with a friend can influence how a patient’s heart or lungs function that day. The interconnectedness becomes clear.

What is the fundamental fact that remains a constant, whether overt or disguised, in all abnormally developed types of personality ? Is it not that so far as emotions are concerned such people live their outward life in terms of inner subjective factors. Their emotional relationships with their outer world are not objectively realistic. They may be intellectually objective in the matter of their correct appraisal of ways and means to their own ends, and in relation to matters that are of no private emotional significance to them. But the moment their personal needs and aims are involved they lose emotional objectivity and behave on the basis of inner mental situations. All patients live in an individual private mental world and to help them we have to discover its structure.

Etiology l Genetic studies provide evidence that bipolar disorder is strongly heritable and that depression is somewhat heritable. l Neurobiological research has focused on the sensitivity of receptors rather than on the amount of various transmitters, with the strongest evidence for diminished sensitivity of the serotonin receptors in depression and mania. There is some evidence that mania is related to heightened sensitivity of the dopamine receptors and that depression is related to diminished sensitivity of dopamine receptors. l Bipolar and unipolar disorders seem tied to elevated activity of the amygdala and the subgenual anterior cingulate and to diminished activity in the dorsolateral prefrontal cortex and hippocampus during tasks that involve emotion and emotion regulation. During mania, greater levels of activation of the striatum have been observed. Mania also may involve elevations in protein kinase C. l Overactivity of the hypothalamic–pituitary–adrenal axis (HPA), as indexed by poor suppression of cortisol by dexamethasone, is related to severe forms of depression and to bipolar disorder. l Socioenvironmental models focus on the role of negative life events, lack of social support, and family criticism as triggers for episodes but also consider ways in which a person with depression may elicit negative responses from others. People with less social skill and those who tend to seek excessive reassurance are at elevated risk for the development of depression. l The personality trait that appears most related to depression is neuroticism. Neuroticism predicts the onset of depression. l Influential cognitive theories include Beck’s cognitive theory, hopelessness theory, and rumination theory. All argue that depression can be caused by cognitive factors, but the nature of the cognitive factors differs across

I was pretty socially awkward as a kid, which is a common thread among animators. You have this need to connect to the rest of the world, but as soon as you do you feel totally awkward and abnormal. And so to relate to the world, you sit and draw.

Even though these individuals had seemed perfectly healthy at birth, something that had happened during their development in the womb affected them for decades afterwards. And it wasn’t just the fact that something had happened that mattered, it was when it happened. Events that take place in the first three months of development, a stage when the foetus is really very small, can affect an individual for the rest of their life. This is completely consistent with the model of developmental programming, and the epigenetic basis to this. In the early stages of pregnancy, where different cell types are developing, epigenetic proteins are probably vital for stabilising gene expression patterns. But remember that our cells contain thousands of genes, spread over billions of base-pairs, and we have hundreds of epigenetic proteins. Even in normal development there are likely to be slight variations in the expression of some of these proteins, and the precise effects that they have at specific chromosomal regions. A little bit more DNA methylation here, a little bit less there. The epigenetic machinery reinforces and then maintains particular patterns of modifications, thus creating the levels of gene expression. Consequently, these initial small fluctuations in histone and DNA modifications may eventually become ‘set’ and get transmitted to daughter cells, or be maintained in long-lived cells such as neurons, that can last for decades. Because the epigenome gets ‘stuck’, so too may the patterns of gene expression in certain chromosomal regions. In the short term the consequences of this may be relatively minor. But over decades all these mild abnormalities in gene expression, resulting from a slightly inappropriate set of chromatin modifications, may lead to a gradually increasing functional impairment. Clinically, we don’t recognise this until it passes some invisible threshold and the patient begins to show symptoms.

In writing the first edition of Japan’s International Relations we aimed to provide a comprehensive analysis of Japan as a normal state, rather than as an aberrant or abnormal state.

The study of abnormality is one of the main ways that power relations are established in society. When an abnormality and its corresponding norm are defined, somehow it is always the normal person who has the power over the abnormal. The psychologist tells us about the madmen, the physician about the patients, the criminologist (or the legal theorist, or the politician) talks about the criminal, but we never expect to hear the latter talk about the former - what they have to say has already been ruled irrelevant, because by definition they have no knowledge (but that is code for not wanting them to have any power).

No need for psychiatric contortions; no shock waves; no need to conjure up deep-seated anxieties and conflicts. It is combat exhaustion—instead of something ominous and mysterious. It is, quite simply, just having had too much. Of course, in more technical terms, combat exhaustion can be thought of as an abnormal reaction to the stress of combat, its manifestation being unique to the person who develops it, channeled into a specific form by the person’s own individual personality and background experience. But it is only one of many abnormal reactions. A soldier who has had too much might choose to surrender or convulsively go forward. He might panic and get killed; he could get himself wounded or wound himself; he might even go to the chaplain or decide on the relative safety of a stockade. He might—if he’s so disposed—develop psychosomatic complaints, get angry, or, in some cases, become totally unreasonable. He can become neurotic, begin to shake, refuse to move, or go completely hysterical. He might even become grossly psychotic—hold imaginary rifles, hear voices, or see his grandmother in every chopper that flies by. “You will be treating these men, and the treatment is simple. For most it will just be rest. In more severe cases, those soldiers whose functioning is beginning to be impaired, who can’t rest, you will medically put to sleep. They are given enough thorazine to put them out and left alone for a day or two. They too, though, like the troopers who are merely resting, stay near the aid station. The more disturbed patients, those troopers who for the moment may be truly disoriented, who have completely stopped functioning, who for any number of reasons appear to need more than a short rest, are sent to an evacuation hospital. But they are never lost to their units. Their group identity is never tampered with, and they know they will be going back. And they do go back. And they are accepted by their units. Believe me, the casual, yet efficient way it is all handled, the official emphasis on health rather than disease, and the lack of mumbo-jumbo have taken the stigma out of having had too much. To the men, it is just something that happens; and more important, it is something they realize can happen to anyone. It is handled that way and it is presented that way. “Gentlemen, it works.

Poor posture and flexibility are common features in patients with CF. CF-related bone disease and abnormal respiratory mechanics lead to a high incidence of musculoskeletal pain, thoracic kyphosis, and vertebral fracture rates. All patients should have an annual musculoskeletal and postural assessment from childhood (age ~8 years), with monitoring and treatment of any musculoskeletal issues (see Chapter 9).

A Family Affair: Essential Fatty Acids More chemical clues to the nature of alcoholism come from research focusing on alcoholics with at least one grandparent who was Welsh, Irish, Scottish, Scandinavian, or native American. Typically, these alcoholics have a history of depression going back to childhood and close relatives who suffered from depression or schizophrenia. Some may have relatives who committed suicide. There also may be a family history of eczema, cystic fibrosis, premenstrual syndrome, diabetes, irritable bowel syndrome, or benign breast disease. The common denominator here is a genetic abnormality in the way the body handles certain essential fatty acids (EFAs) derived from foods. Normally, these EFAs are converted in the brain to various metabolites such as prostaglandin E1 (PGE1), which plays a vital role in the prevention of depression, convulsions, and hyperexcitability. When the EFA conversion process is defective, brain levels of prostaglandin E1 are lower than normal, which results in depression. In affected individuals, alcohol acts as a double-edged sword. It activates the PGE1 within the brain, which immediately lifts depression and creates feelings of well-being. Because the brain cannot make new PGE1 efficiently, its meager supply of PGE1 is gradually depleted. Over time, the ability of alcohol to lift depression slowly diminishes. Several years ago, researchers hit upon a solution to this problem. They discovered that a natural substance, oil of evening primrose, contains large amounts of gamma-linolenic acid (GLA), which can help the brain convert EFAs to PGE1. The results are quite dramatic. In a recent study in Scotland, researcher David Horrobin, M.D., matched two groups of alcoholics whose EFA levels were 50 percent below normal. The first group got EFA replacement, the second, a placebo. Marked differences between the two groups emerged in the withdrawal stage. The group that got EFA replacement had far fewer symptoms, while the placebo group displayed the full range of withdrawal symptoms associated with prostaglandin deficiency: tremors, irritability, tension, hyperexcitability, and convulsions. At the outset of the study, members of both groups had some degree of alcohol-related liver damage. Three months later, the researchers found that liver function among the EFA replacement group was almost normal. There was no significant improvement among the placebo group. A year later, the placebo group was still deficient in the natural ability to convert essential fatty acids into PGE1. What’s more, only 28 percent of this group had remained sober; the rest had resumed drinking. Results were dramatically better among the EFA replacement group: 83 percent remained sober and depression free.

Reprogramming is what John Gurdon demonstrated in his ground-breaking work when he transferred the nuclei from adult toads into toad eggs. It’s what happened when Keith Campbell and Ian Wilmut cloned Dolly the Sheep by putting the nucleus from a mammary gland cell into an egg. It’s what Yamanaka achieved when he treated somatic cells with four key genes, all of which code for proteins highly expressed naturally during this reprogramming phase. The egg is a wonderful thing, honed through hundreds of millions of years of evolution to be extraordinarily effective at generating vast quantities of epigenetic change, across billions of base-pairs. None of the artificial means of reprogramming cells comes close to the natural process in terms of speed or efficiency. But the egg probably doesn’t quite do everything unaided. At the very least, the pattern of epigenetic modifications in sperm is one that allows the male pronucleus to be reprogrammed relatively easily. The sperm epigenome is primed to be reprogrammed6. Unfortunately, these priming chromatin modifications (and many other features of the sperm nucleus), are missing if an adult nucleus is reprogrammed by transferring it into a fertilised egg. That’s also true when an adult nucleus is reprogrammed by treating it with the four Yamanaka factors to create iPS cells. In both these circumstances, it’s a real challenge to completely reset the epigenome of the adult nucleus. It’s just too big a task. This is probably why so many cloned animals have abnormalities and shortened lifespans. The defects that are seen in these cloned animals are another demonstration that if early epigenetic modifications go wrong, they may stay wrong for life. The abnormal epigenetic modification patterns result in permanently inappropriate gene expression, and long-term ill-health.

Even when behaviors are clearly stress-related, they can be difficult to interpret. Mel Richardson was once asked to examine a tree kangaroo at the San Antonio Zoo that the keepers said was acting bizarrely. With the ears of a teddy bear, the rounded chub of a koala, and the tail of a fuzzy monkey, tree kangaroos are very cute. But this female was acting vicious. She was attacking her babies, and the keepers had no idea why. Mel went to check on her. Sure enough, as soon as he approached, the kangaroo ran to her babies and started hitting and clawing at them with her paws. He stepped back, and she stopped. He walked forward, and she ran at the babies again. “I realized,” said Mel, “that she wasn’t viciously attacking her babies at all. She was trying to pick them up off the floor, but her little paws weren’t meant for that. In her native Australia and Papua New Guinea her babies never would have been on the ground. Her whole family would have been up in the trees.” The mother kangaroo wanted to move the babies away from the humans. What looked like abnormal attacks on her young were actually her way of trying to protect them. Her behavior wasn’t mental illness at all but a response to the stress of being a mother in an unnatural environment. After the keepers redesigned the kangaroos’ cage so that more of it was elevated and farther from the door, she relaxed and stopped hitting her babies. Mel explained, “As flippant as it might sound, the truth is that in order to know what’s abnormal, you must first know what’s normal. In this case in order to determine pathology, I had to understand the animal’s psychology. It’s pretty easy for people to get this wrong.

It was true, of course, there was an abnormal level of narcissism in our society, but it did not do, he told himself, to spend too much time going on about it. Society changed. Narcissism was about love, ultimately, even if only love of self. And that was better than hate. By and large, Hate, of all the tempting gods, was the unhappiest today. He had his recruits, naturally, but they were relatively few, and vilified. Did it matter if young men thought of fashion and hair gel when, not all that many years ago, their thoughts had tended to turn to war and flags and the grim partisanship of the football terrace?

The Biology of Animal Stress, prenatal exposure to elevated levels of stress hormones, such as cortisol and adrenaline, can set puppies up to develop abnormal brain chemistries, specifically, an abnormal regulation in the pathway between the hypothalamus in the brain and the adrenal glands (glands that produce stress-related hormones), called the hypothalamic-pituitary-adrenal (HPA) axis. HPA axis abnormalities can lead to anxiety, fear, and even aggression problems as adults.

Nearly all diseases that have baffled the medical profession may be traced to some deficiency in our diet, and it may be truthfully said, that at least ninety per cent of human ailments are traceable to inadequate and faulty nutrition. Yet in no part of study and observation has medical need been more insufficiently met than in that of rational dietetics, both in relation to the maintenance of health, and in the treatment and prevention of disease. By far the most detrimental effect of faulty nutrition is the result of habitual errors of one kind or another, which are not sufficiently grave to command immediate attention. For instance, we may abuse our pancreas and kidneys for years, without the feeling of pain, until these organs are finally injured beyond repair. It is the gradual operation of more or less constant, but unperceived causes, rather than of accidental exposures to abnormal conditions, which in most cases are responsible for undermining the health of the individual

Followers of Christ are not called to be merely tolerant of others. We are called to love those who disagree with us. Abnormal communication - blessing those who curse us - establishes the relational level of our communication and demonstrates our concern for others.

Again, my heart is a scale out of balance, with my end taking all the weight.

Hep´-er-in.”  The very first mast cell mediator to be discovered (in the 1930s!), heparin’s principal function is to inhibit blood clotting.  As a result, in some mast cell disease patients, a flare of their mast cell disease can result in a micro-flood of heparin being released by their abnormal mast cells into the surrounding tissues, causing bleeding which often seems quite mysterious to the doctor (and patient!) because all of the usual tests for bleeding disorders don’t show anything wrong with the coagulation system.  This is because these tests look for systemic bleeding disorders, whereas mast-cell-heparin-related bleeding usually is just a local bleeding disorder confined to the particular tissue in which the abnormally activated mast cells are abnormally making and releasing heparin – so there truly isn’t anything wrong with the coagulation system

The real hopeless victims of mental illness are to be found among those who appear to be most normal. . .they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted.

In a report that brought together findings from studies over the past forty years of more than 100,000 employed women, those working irregular nighttime hours resulting in poor-quality sleep, such as nurses who performed shift work (a profession occupied almost exclusively by woman at the time of these earlier studies), had a 33 percent higher rate of abnormal menstrual cycles than those working regular daytime hours. Moreover, the woman working erratic hours were 80 percent more likely to suffer from issues of sub-fertility that reduced the ability to get pregnant. Woman who do become pregnant and routinely sleep less than eight hours a night are also significantly more likely to suffer a miscarriage in the first trimester, relative to those consistently sleeping eight hours or more a night.

She said, you need knowledge. Getting to the essence of a story takes a deep understanding of the topic, its context, its fit into the bigger picture, and its relationship to different fields. So she would read all the related news and try to spot the one piece of information that all others had missed or hadn’t focused enough on. “My goal,” she said, “was to understand the ‘spiderweb’ of the story because that is what allowed me to spot any ‘abnormal’ or ‘unusual’ detail or behavior that didn’t quite fit into the natural course of the story.

The real hopeless victims of mental illness are to be found among those who appear to be most normal. Many of them are normal because they are so well adjusted to our mode of existence, because their human voice has been silenced so early in their lives, that they do not even struggle or suffer or develop symptoms as the neurotic does. They are normal not in what may be called the absolute sense of the word; they are normal only in relation to a profoundly abnormal society. Their perfect adjustment to that abnormal society is a measure of their mental sickness. These millions of abnormally normal people, living without fuss in a society to which, if they were fully human beings, they ought not to be adjusted.

When we come to this primary union of you and the person next to you, we find that marriage not only involves a union of bodies but a union of souls. What is the relation between them? Is bodily union a vestibule to soul union or vice versa? A mother kissing and hugging her son back from a European concentration camp gives a real clue to the relationship. Anybody describing this kissing and hugging between mother and son as a bodily action would miss its larger and fuller import in the soul union there. However, if there were not these embraces and kisses between the long-separated mother and son, manifesting deep soul unity, they would be very abnormal people.

Although all this abnormal order of things is not of recent date, the characteristic fact of the bourgeois period is that it assumed the principal, dissociated, and autonomous characteristics of a "social morality"—precisely with the "virtuism" of which Pareto accuses it, which to a certain extent was no longer subject to religious morality. Now, it is exactly this morality with a sexual basis that is the principal object of the processes of dissolution in recent times. We hear of a "sexual revolution" supposed to remove both inner inhibitions and repressive social taboos. In fact, in today’s world "sexual freedom" is being affirmed ever more, as a current practice. But we have to consider this in more detail. I must emphasize above all that the direction of the processes at work is toward a freeing of sex, but in no way a freeing from sex. Sex and women are instead becoming dominant forces in present society, an evident fact that is also part of the general phenomenology of every terminal phase of a civilization’s cycle. One might speak of a chronic sexual intoxication that is profusely manifested in public life, conduct, and art. Its counterpart is a gynocratic tendency, a sexually oriented preeminence of the woman that relates to the materialistic and practical involvement of the masculine sex: a phenomenon that is clearest in those countries, like the United States, where that involvement is more excessive. [...] The aspects of the crisis of female modesty are another part of this. Beside the cases in which almost full female nudity feeds the atmosphere of abstract, collective sexuality, we should consider those cases in which nudity has lost every serious "functional" character—cases which by their habitual, public character almost engender an involuntarily chaste glance that is capable of considering a fully undressed girl with the same aesthetic disinterest as observing a fish or a cat. Furthermore, by adding the products of commercialized mass pornography, the polarity between the sexes is diluted, as seen in the conduct of "modern" life where the youth of both sexes are everywhere intermingled, promiscuously and "unaffectedly," with almost no tension, as if they were turnips and cabbages in a vegetable garden. We can see how this particular result of the processes of dissolution relates to what I have said of the "animal ideal," as well as the correspondence between the East and the West. The primitive, erotic life so typical among American youth is not at all far from the promiscuity of male and female "comrades" in the communist realm, free from the "individualistic accidents of bourgeois decadence," who in the end reflect little on sexual matters, their prevalent interests being channeled elsewhere into collective life and class. We can consider separately the cases in which the climate of diffuse and constant eroticism leads one to seek in pure sexuality, more or less along the same lines as drugs, frantic sensations that mask the emptiness of modern existence. The testimonies of certain beatniks and similar groups reveal that their pursuit of the sexual orgasm causes an anguish aroused by the idea that they and their partner might not reach it, even to the point of exhaustion.

10 Common Reasons for IVF Failure  In-vitro fertilization or IVF provides a means towards parenthood to couples struggling with natural pregnancy. Although IVF is a successful, safe, and effective technique some couples may struggle with multiple IVF failures. According to Dr Vandana Narula, MBBS, MD (Obstetrics & Gynaecology), a lot of factors contribute to the success or failure of IVF. The best infertility specialist in sector 43 Chandigarh advises you to not lose hope and discuss the opportunities with your doctor. 10 Common Reasons for IVF Failure The infertility & IVF specialist in Mohali gives the following common reasons for IVF failure: 1. Poor Sperm Quality The quality of sperm determines the quality of the embryo. Men with certain medical conditions including azoospermia or diabetes may procedure poor quality and quantity of sperm. This can either hamper the development of the embryo or lead to an abnormal embryo. 2. Low Anti-Mullerian Hormone (AMH) Values AMH is a hormone secreted by cells in the egg. A good level of AMH in the woman’s blood indicates good ovarian reserve. Women with low AMH values may procedure unhealthy eggs that may not be implanted. 3. Implantation Failure Implantation failure is one of the common causes of IVF failures. It is usually caused by: A non-receptive uterus lining, thin lining, or lining affected by genital tuberculosis. Prevailing immunological conditions make the uterine environment hostile for the embryos. The endometrium has an inbuilt mechanism to reject poor-quality embryos. 4. Poor Quality of Eggs and Embryos The quality of eggs plays a significant role in IVF failure. The quality of eggs is directly related to the age of a woman and her health. The human egg consists of 23 chromosomes. If any of these chromosomes are missing or arranged incorrectly, they can produce abnormal embryos. A woman’s age also plays a key role in the egg quality. With advancing age, the eggs become less healthy and are prone to genetic abnormalities. This can make it difficult for them to be fertilized by sperm and lead to abnormal embryos.

Depression may seem completely useless. Even apart from the risk of suicide, sitting all day morosely staring at the wall can't get you very far. A person with severe depression typically loses interest in everything -work, friends, food, even sex. It is as if the capacities for pleasure and initiative have been turned off. Some people cry spontaneously, but others are beyond tears. Some wake every morning at 4 A.M. and can't get back to sleep; others sleep for twelve or fourteen hours per day. Some have delusions that they are impoverished, stupid, ugly, or dying of cancer. Almost all have low self-esteem. It seems preposterous even to consider that there should be anything adaptive associated with such symptoms. And yet depression is so frequent, and so closely related to ordinary sadness, that we must begin by asking if depression arises from a basic abnormality or if it is a dysregulation of a normal capacity.

This passage is not encouraging unwise activity that overloads your schedule with church events and obligations. Nor does it ask you to turn normal relational moments into abnormal witnessing encounters.

Perhaps you may relate to Tom in one way or another. Maybe when you’re in a crowded place, and you hear a group of people laughing, you instantly panic because you think they’re making fun of you, or you feel like you’re always being judged when you’re around strangers (or even your friends). Maybe you can’t stop yourself from constantly thinking back to past mistakes and better ways you would have approached the situation, no matter how great your life is currently. Much like Tom, these feelings are not abnormal.

The exquisite watch towers, the gold and green memorial archways, the vermillion city gates, and the pavilion at Jiangshan Park were silent, as if listening to a sound they might never hear again. The wind blew, like a mournful sigh, snaking through the palace towers and the halls, as if wanting to relate tales of days past… The bridge was practically deserted. Dull moonlight shone down, cold and desolate, on expanses of ice on both sides. Dim outlines of distant pavilions cast dark shadows… with only their yellow roof tiles glimmering faintly. A white pagoda reaching into the hazy clouds cast a desolate chill on everything, causing the three lakes to reveal their northern bleakness… As he was crossing the bridge, Xiangzi shivered from the icy expanse below and refused to go any farther. Normally, when he was pulling his rickshaw across the bridge, he concentrated on his feet, afraid of a misstep, as if the sights around him did not exist. Now he was free to look, but the scenery frightened him. The cold, gray ice, the rustling trees, and the deathly pale pagoda were so forlorn… Even the white stones of the bridge at his feet seemed abnormally bleak and so white that even the street lamps were subdued and dreary. He did not want to move, he did not want to look, and he definitely did not want to be with her.

The pathogenesis of otitis media in these individuals may be related to abnormal anatomy causing Eustachian tube dysfunction. Balance testing was abnormal, Eustachian tube function tests revealed dysfunction of tube. Surgery was performed to replace the obstructed tube with a patent one, and an adenoidectomy and bilateral inferior turbinate reduction to relieve the chronic nasal obstruction. Postoperatively balance testing was normal, Eustachian tube function remained dysfunctional, but she had complete resolution of her vertigo following the surgery.

The medical name for this condition is Non-Alcoholic Fatty Liver Disease (NAFLD) and it describes a range of conditions in which the liver tests are abnormal in people who drink little or no alcohol. It ranges from a mild condition in which excess fat is deposited in the liver causing slightly abnormal liver tests to a more serious condition in which the fat in the liver leads to inflammation, scarring and cirrhosis, which is irreversible liver damage. NAFLD is very common and may be found in up to 1 in 5 adults. Of those with NAFLD, about 1 in 4 will develop the more serious form leading to cirrhosis. This is a very slow process and may progress over years to liver failure. It is related to obesity and as in the metabolic syndrome (see previous question) insulin resistance is the underlying cause. There

Driver Behavior & Safety Proper driving behavior is vital for the safety of drivers, passengers, pedestrians and is a means to achieve fewer road accidents, injuries and damage to vehicles. It plays a role in the cost of managing a fleet as it impacts fuel consumption, insurance rates, car maintenance and fines. It is also important for protecting a firm’s brand and reputation as most company- owned vehicles carry the company’s logo. Ituran’s solution for driver behavior and safety improves organizational driving culture and standards by encouraging safer and more responsible driving. The system which tracks and monitors driver behavior using an innovative multidimensional accelerometer sensor, produces (for each driver) an individual score based on their performance – sudden braking and acceleration, sharp turns, high-speed driving over speed bumps, erratic overtaking, speeding and more. The score allows fleet managers to compare driver performance, set safety benchmarks and hold each driver accountable for their action. Real-time monitoring identifies abnormal behavior mode—aggressive or dangerous—and alerts the driver using buzzer or human voice indication, and detects accidents in real time. When incidents or accidents occurs, a notification sent to a predefined recipient alerts management, and data collected both before and after accidents is automatically saved for future analysis. • Monitoring is provided through a dedicated application which is available to both fleet manager and driver (with different permission levels), allowing both to learn and improve • Improves organizational driving culture and standards and increases safety of drivers and passengers • Web-based reporting gives a birds-eye view of real-time driver data, especially in case of an accident • Detailed reports per individual driver include map references to where incidents have occurred • Comparative evaluation ranks driving according to several factors; the system automatically generates scores and a periodic assessment certificate for each driver and/or department Highlights 1. Measures and scores driver performance and allows to give personal motivational incentives 2. Improves driving culture by encouraging safer and more responsible driving throughout the organization 3. Minimizes the occurrence of accidents and protects the fleet from unnecessary wear & tear 4. Reduces expenses related to unsafe and unlawful driving: insurance, traffic tickets and fines See how it works:

But the insight is psychotic because it is based on delusions not on adaptive and life-promoting ways of relating to whatever threats precipitated the panic. The delusions, in other words, allow the panic-stricken individual to escape from the flood of negative emotions, but at the cost of losing touch with reality and for this reason Arieti says that a psychotic break can be viewed as “an abnormal way of dealing with an extreme state of anxiety. . .

Compassion constitutes a radical form of criticism, for it announces that the hurt is to be taken seriously, that the hurt is not to be accepted as normal and natural but is an abnormal and unacceptable conditions for humanness. In the arrangement of “lawfulness” in Jesus’ time, as in the ancient empire of Pharaoh, the one unpermitted quality of relation was compassion. Empires are never built or maintained on the basis of compassion.

prison doctor Josef Brinsteiner examined Hitler and diagnosed a “right-sided cryptorchidism,” a non-descended testicle that he had since birth or early infancy. That spelled the end of rumours that Hitler had lost a testicle in 1916 when he was wounded in the First World War. The discovery also means that my assumption in the first volume of this biography that Hitler had normally developed sexual organs must be corrected. We can only speculate about the effects this physical anomaly may have had. Perhaps it explains Hitler’s reluctance to appear naked before others and was one cause of his difficult relations with women. It is very likely that the abnormality strengthened the feelings of inferiority Hitler carried from his failures

In the cybernetic universe where everything is calculable, can't Evil in the sense of disorder and chaos slip into and penetrate the integral reality of the network? Isn't that what hackers do for example? Accidents are involved, certainly. Paul Virilio speaks of this much better than I can. But what I am saying is of another order: it is unpredictable. It is power turning against itself. It is not necessarily the apocalypse but it is a disaster in the sense of a form made irrepressible regardless of the will of the actors and their negative actions or sabotage. Certainly, many negative things can happen to the system, but it will always be an objective or objectal negativity related to the technology itself, not a symbolic irruption. I am afraid that this game remains internal to integral reality. Perhaps there are some who can penetrate the cracks in this cybernetic universe? I must say that I do not know the internal rules of the game for this world, and I do not have the means to play it. This is not a philosophical or moral disavowal or prejudice on my part. It is just that I am situated somewhere else and I cannot do otherwise. From the outside, I can see that everything works and that the machine allows everything to function. Let us allow that system to proceed normally - or abnormally- until it runs its course; let us leave to the machine what belongs to the machine without trying to humanize it or make it an anthropoid object. For me, I will always have an empty, perfectly nonfunctional and therefore free space where I can express my thoughts. Once the machine has exhausted all of its functions, I slip into what is left, without trying to judge or condemn it. Judgment is foreign to the radicality of thought. This thinking has nothing scientific, analytic or even critical about it, since those aspects are now all regulated by machines. And maybe a new spacetime domain for thought is now opening?

It is not only the highly creative who would not whole-heartedly agree with Bowlby’s contention that intimate attachments to other human beings are the hub around which a person’s life revolves. For the deeply religious, and especially for those whose vocation demands celibacy, attachment to God takes precedence over attachment to persons. Although such people may succeed in loving their neighbours as themselves, the injunction ‘Thou shalt love the Lord thy God with all thy heart and with all thy soul, and with all thy mind’ is truly ‘the first and great commandment’.15 Throughout most of Europe’s recorded history, it was assumed that ultimate happiness was not to be expected from human relationships and institutions, but could only be found in man’s relation with the divine. Indeed, many of the devout believed that human relationships were an obstacle to communion with God. The founders of the monastic movement were the hermits of the Egyptian desert, whose ideal of perfection was only to be achieved through renunciation of the world, mortification of the flesh, and a solitary life of contemplation and rigorous discipline. It was recognized very early that the life of the anchorite was not possible for everyone, and so the ‘coenobitic’ tradition arose in which monks no longer lived alone but shared the life of dedication to God in communities. Intimate attachments, or desires for such attachments, are not unknown within the walls of monasteries, but they are regarded as intrusive distractions and firmly discouraged. Although learning was not a necessary feature of monastic life, the libraries of the monasteries preserved the learning of the past, and attracted those monks who had scholarly interests. In the twelfth and thirteenth centuries, the monasteries led an intellectual revival, and were pre-eminent in history and biography.16 Perhaps monastic discipline and the absence of close personal ties not only facilitated the individual’s relation with God, but also fostered scholarship. It would, I think, be quite wrong to assume that all those who have put their relation with God before their relations with their fellows are abnormal or neurotic. Some of those who choose the monastic or celibate life certainly do so for the ‘wrong’ reasons: because their human relationships have failed, or because they dislike taking responsibility, or because they want a secure haven from the world. But this is not true of all; and even if it were so, would not imply that a life in which intimate attachments to other human beings played little part was necessarily incomplete or inferior. The religious person might argue that modern psycho-analysts have idealized intimate attachments; that human relationships are, because of the nature of man, necessarily imperfect; and that encouraging people to look for complete fulfilment in this way has done more harm than good.

Metabolic syndrome changes the vocabulary that physicians use when they discuss a patient’s risk of heart disease. High cholesterol isn’t among the cluster of metabolic abnormalities, nor is elevated LDL cholesterol, the “bad” cholesterol. Rather, the key factors are high triglycerides, low HDL cholesterol, high blood pressure, overweight, glucose intolerance, and, more than anything, the condition of being insulin-resistant and thus oversecreting insulin, day in and day out. All of these abnormalities happen to be related to the carbohydrate content of the diet, not to the fat content.

This brief family history obviously does not demonstrate frank insanity, such as psychosis, mania, or severe depression. But it does suggest that FDR’s relatives had personalities abnormal enough to arouse the attention of average people.

Article F: Alternobaric Vertigo and Eustachian Tube Dysfunction. Charles D. Bluestone, MD; J. Douglas Swarts, PhD; Joseph M. Furman, MD, PhD; Robert F. Yellon, MD. Case Report: Persistent Alternobaric Vertigo at Ground Level due to Chronic Toynbee phenomenon. Laryngoscope 2012;122(4):868–72. The term “alternobaric vertigo” was coined by Lundgren in 1965 to describe vertigo in deep-sea divers, but also referred to aircraft pilots in 1966. It occurs during ascent and rarely descent and is a result of asymmetrical middle-ear pressures. Classically the vertigo due to this pathogenesis is transient but may last for several minutes. It is frequently associated with nausea and vomiting. It has been reproduced in pressure chamber experiments with some divers and fliers, but has not been reported spontaneously at ground level (Figure F–1). FIGURE F–1. Alternobaric vertigo can occur during ascent in an airplane or when scuba diving. We encountered a 15-year-old female with bilateral tympanostomy tubes who manifested persistent severe vertigo, at ground level, secondary to a unilateral middle-ear pressure of +200 mm H2O elicited by an obstructed tympanostomy tube in the presence of chronic nasal obstruction. She had had long-term tubes placed due to recurrent and chronic otitis media. Physical examination revealed achondroplasia, which is an autosomal dominate disorder characterized by abnormal bone growth, short arms and legs, short stature and a large head, which is associated with otitis media. The pathogenesis of otitis media in these individuals may be related to abnormal anatomy causing Eustachian tube dysfunction. Balance testing was abnormal, Eustachian tube function tests revealed dysfunction of tube. Surgery was performed to replace the obstructed tube with a patent one, and an adenoidectomy and bilateral inferior turbinate reduction to relieve the chronic nasal obstruction. Postoperatively balance testing was normal, Eustachian tube function remained dysfunctional, but she had complete resolution of her vertigo following the surgery. FIGURE F–2. Pathogenesis of alternobaric vertigo due to the “Toynbee phenomenon” One tympanostomy was obstructed and when swallowing, she developed high positive pressure in the middle ear, but in the ear with a patent tube, the pressure did not remain in the middle ear. We believed this was a previously unreported scenario in which closed-nose swallowing insufflated air into her middle ears, resulting in sustained positive middle-ear pressure in the ear with the obstructed tube. Swallowing, when the nose is obstructed, can result in abnormal negative or positive pressures in the middle ear, which has been termed the “Toynbee phenomenon.” We concluded that in patients who have vertigo, consideration should be given to the possibility that nasal obstruction and the “Toynbee phenomenon” are involved (Figure F–2). CHAPTER 7 PATHOLOGY The pathology of the ET may or may not be involved in the pathogenesis of otitis media, whereas the

At the Laboratory of Cognitive Neuroscience in Lausanne, Switzerland, scientists have been studying the link between mystical experiences and cognitive neuroscience. They point out that the fundamental revelations to the founders of the three monotheistic religions—Moses, Jesus, and Mohammed—occurred on mountains, and included such components as feeling a presence, seeing a figure, hearing voices, and seeing lights. These similarities of experience suggest to the scientists that exposure to altitude might affect functions relying on brain areas such as the temporoparietal junction and the prefrontal cortex. Prolonged stays at high altitude, especially when linked to social deprivation, can lead to prefrontal lobe dysfunctions, which are commonly found during ecstatic experiences. Also, the physical and emotional stresses of climbing at altitude release endorphins, which are known to lower the threshold for temporal lobe epilepsy, which in turn might evoke such experiences. All such phenomena, then, might relate to “abnormal body processing.

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If we could begin to see much illness itself not as a cruel twist of fate or some nefarious mystery but rather as an expected and therefore normal consequence of abnormal, unnatural circumstances, it would have revolutionary implications for how we approach everything health related. The ailing bodies and minds among us would no longer be regarded as expressions of individual pathology but as living alarms directing our attention toward where our society has gone askew, and where our prevailing certainties and assumptions around health are, in fact, fictions. Seen clearly, they might also give us clues as to what it would take to reverse course and build a healthier world.